查询词典 peripheric receptor

The holding potential was -70mV.(2) By whole-cell voltage-clamp technique, after slices were preincubated with glycine receptor competitive antagonist alone or with GABA〓 receptor competitive antagonist alone or with GABA〓 receptor incompetitive antagonist alone or with GABA〓 receptor and glycine receptor competitive antagonists collaterally or with GABA〓 receptor incompetitive antagonist and glycine receptor competitive antagonist collaterally, the effects of 100μM propofol on EPSCs of the CA1 neurons of the rat hippocampus were investigated. The holding potential was -70mV.

2应用全细胞膜片钳技术，观察100M丙泊酚对单纯用甘氨酸受体竞争性拮抗剂预孵、单纯用GABA〓受体竞争性拮抗剂预孵、单纯用GABA〓受体非竞争性拮抗剂预孵、合用GABA〓受体和甘氨酸受体竞争性拮抗剂预孵以及合用GABA〓受体非竞争性拮抗剂和甘氨酸受体竞争性拮抗剂预孵的大鼠海马脑片CA1区电刺激诱发的EPSC的影响。

The anatomical localizations indicate that Al receptor and Dl receptor coexist in strionigro-strioentopeduncular neurons, and A2a receptor and D2 receptor coexist in striopallidals neurons. The heteromeric complexes of Al/D1、A2a/D2 receptor provided the molecular basis for the functional interactions of Al/Di and A2a/D2 receptor.

腺苷A1受体和多巴胺D1受体以及腺苷A2a受体和多巴胺D2受体分别共存於基底神经节中纹状体向黑质和脚内核投射的神经元以及纹状体向苍白球投射的神经元内。A1/D1、A2a/D2受体形成受体异聚复合体构成了受体一受体之间相互作用的分子基础。

Glycine receptor competitive antagonist partially reversed the effects of propofol. When slices were preincubated with GABA〓 receptor and glycine receptor competitive antagonists collaterally or preincubated with GABA〓 receptor incompetitive antagonist and glycine receptor competitive antagonist collaterally, 100μM propofol still decreased the amplitude of EPSCs.

2在膜钳制电压为-70mV条件下，100M丙泊酚明显降低合用GABA〓受体和甘氨酸受体竞争性拮抗剂预孵的大鼠海马脑片CA1区电刺激诱发的EPSC幅值，下降程度小于单纯甘氨酸受体竞争性拮抗剂预孵组，大于单纯GABA〓受体竞争性拮抗剂预孵组；而且，100M丙泊酚更是明显降低合用GABA〓受体非竞争性拮抗剂和甘氨酸受体竞争性拮抗剂预孵的大鼠海马脑片CA1区电刺激诱发的EPSC幅值，下降程度甚至大于单纯甘氨酸受体竞争性拮抗剂预孵组。

Although the intact-receptor based biosensors of the maxillary palp of cockroach Periplaneta Americana are not yet practical analytical devices at present. Yet, sensitive and selective responses to biomolecules involving amino acids and protein, as well as some simple substance such as salts and sugars have been firstly obtained. It is already evident that receptor based biosensors are enormously superior to isolated receptor biosensors in terms of response time and recovery times, thus, the intact receptor biosensor worth of further investigation and development.

总而言之，本论文首次从电生理信号上对美洲蜚蠊下颚须的化学响应进行研究，初步探讨了基于美洲蜚蠊下颚须的整合受体生物传感器的特性；发现了美洲蜚蠊下颚须能够整合其密集的感觉毛阵列对化学刺激的响应；得到了蜚蠊对氨基酸和蛋白质等生物分子以及简单物质如盐和糖等的敏感而具有选择性的响应信号，并发现了糖和蛋白质的特殊响应信号；表明了美洲蜚蠊下颚须是一种新型整合受体生物传感器的敏感材料，进一步深入地研究信号波形及其整合原理、探寻糖和蛋白质的特殊受体细胞等，对这一类型整合受体传感器的研究发展是很有意义的。

TGF-βbinds to a heteromeric complex of type I and type II receptors. The constitutively active type II receptor phosphorylates and activates the type I receptor which phosphorylates Smad2 and Smad3 (receptor-associated Smads). Receptor-associated Smads bind the common mediator Smad4 and are translocated to the nucleus, where they associate with DNA-binding cofactors to modulategene transcription.

TGF-β与其效应细胞表面的Ⅱ型受体TβRⅡ和Ⅰ型受体TβRⅠ形成的异源二聚体结合，相继激活TβRⅡ和TβRⅠ，活化的TβRⅠ再进一步活化Smad2和Smad3，磷酸化的Smad2/3必须与Smad4结合形成复合物，才能进入细胞核，调节靶基因的转录[6]。

Erve growth factor can combine with its" receptor (one of tyrosine protein kinase receptor coded by proto - oncogene tyrosine kinase, TrkA), Causing the molecule of receptors to gather on the cell surface, and the tyrosine protein in cytoplasmic domain may be activated, three tyrosine base in the kinase domain of its" receptor and two tyrosine base at other domain be phosphated, thus, phosphated tyrosine receptor kinase became the bracket which absorb all kinds of connective proteins and kinases.

GF与其酪氨酸受体激酶受体(由原癌基因trk编码的一种酪氨酸蛋白激酶受体，TrkA)相结合，引起受体分子在细胞表面发生二聚体化，然后受体细胞内结构上酪氨酸活性被激活，使受体自身结构中位于激酶结构域的三个酪氨酸残基及在此结构域外的两个酪氨酸残基发生自身磷酸化，这样，磷酸化的酪氨酸受体激酶A便成为吸收各种连接蛋白质和酶的支架。

The affected chicks acquired the morphine conditioned place preference more quickly, and maintained it much longer. Experiment 3 showed that during E5-8, injecting delta receptor antagonist naltrindole reversed the learning and memory impairment caused by morphine while delta receptor agonist DPDPE impaired learning and partial memory function. On the other hand, mu opioid receptors had little effect. As for E17-20, given naloxonazine can reverse the increases of susceptibility to morphine, and the mu receptor agonist DAGO cause the increases of susceptibility to morphine. Delta receptors have no effect.

研究结果发现：经过对鸡胚发育不同时间段的吗啡给药，胚胎期发育E5-8阶段给予吗啡的小鸡学习记忆受损最为严重，表现为学习和记忆功能的严重下降；而E17-20时段吗啡给药的小鸡更容易获得吗啡CPP且保持时间更长。E5-8阶段给予delta受体拮抗剂natrindole能够翻转吗啡对学习和记忆的损害作用，并且给予delta受体激动剂DPDPE也损害学习和部分记忆功能，mu受体作用不大。E17-20阶段拮抗mu受体能够抑制成瘾易感性的增加，激动mu受体可以增加小鸡的成瘾易感性，delta受体没有明显作用。

EAA neurotransmitter Gly increased the sensitivity of the ligand Asp and Glu to theNMDA receptor, thus increased the NMDA receptor activity and cytosolic Ca2 + in the bilirubin precipi-tated brain tissue. NMDA receptor antagonist GAPA could prevent the cytosolic Ca2 + overload, and re-lieve brain edema.

NMDA受体过度活化致细胞内Ca2+超载参与介导胆红素神经毒性，NMDA受体拮抗剂可望成为胆红素神经毒性防治的重要途径。

Interleukin-1 receptor-associated kinase-4 (IRAK-4), a member of the IRAK family, plays an essential role in Toll-like receptor- and IL-1 receptor-mediated signaling..

白细胞介素1受体相关激酶4，白细胞介素1受体相关激酶家族的一员，在Toll样受体和白介素1受体介导的信号通路中发挥关键作用。

Mannose receptor is one member of the mannose receptor family and belongs to C-type lectin receptor.

甘露糖受体为甘露糖受体家族的成员，属于C型凝集素受体。

Aquatic or marsh-growing fern allies; known to have existed since the Cenozoic; sometimes included in Lycopodiales.

生活于水中或湿地的蕨类；从新生代生存至今；有时归于石松目之中。

The engine was uprated from a 90hp Franklin to a 125hp Lycoming.

改良过的引擎是从90hp到125hp莱康明富兰克林。