查询词典 mutated

1,After transfected the mutated mtDNA of colorectal carcinoma,the mtDNA D-loop region of the transfected cells displays new mutation points.2,The external source pieces of the mutated mtDNA can integrate to nuclear genome after transfection.3,There's no differences in apoptosis between combinations after transfected the mutation of mtDNA in NIH3T3 and LST cells.4,The mutated mtDNA may affect the action mechanism of occurrence and development in colorectal carcinoma through affecting its mtDNA mutation or integrating exogenetic mtDNA to its nuclear which may cause the abnormal expression of oncogene or anti-oncogene.

（1）转染突变的大肠癌细胞mtDNA后转染细胞的mtDNA均可发生多处的突变位点。（2）通过转染后突变的外源性的mtDNA可以整合到核基因组内。（3）突变的mtDNA转染LST细胞及NIH3T3细胞后，不影响转染细胞的凋亡改变。（4）mtDNA的突变可能通过影响体细胞mtDNA的突变和通过外源性mtDNA在核内的整合从而影响癌基因或抑癌基因的表达异常，从而参与肿瘤的发生发展。

1,After transfected the mutated mtDNA of colorectal carcinoma,the mtDNA D-loop region of the transfected cells displays new mutation points.2,The external source pieces of the mutated mtDNA can integrate to nuclear genome after transfection.3,There's no differences in apoptosis between combinations after transfected the mutation of mtDNA in NIH3T3 and LST cells.4,The mutated mtDNA may affect the action mechanism of occurrence and development in colorectal carcinoma through affecting its mtDNA mutation or integrating exogenetic mtDNA to its nuclear which may cause the abnormal expression of oncogene or anti-oncogene.

（1）转染突变的大肠癌细胞mtDNA后转染细胞的mtDNA均可发生多处的突变位点。（2）通过转染后突变的外源性的mtDNA可以整合到核基因组内。（3）突变的mtDNA转染LST细胞及NIH3T3细胞后，不影响转染细胞的凋亡改变。（4）mtDNA的突变可能通过影响体细胞mtDNA的突变和通过外源性mtDNA在核内的整合从而影响癌基因或抑癌基因的表达异常，从而参与肿瘤的发生发展。线粒体DNA；D―环区；突变；质粒；pcDNA3.1；转染

The amino acid sequence of the mutated saccharomyces cerevisiae starting transcription factor disclosed by the present invention is shown as SEQ ID No: 2, and the mutated saccharomyces cerevisiae starting transcription factor transformed into microzyme can increase the efficiency of the xylose utilization and glucose-xylose co-utilization of leaven.

本发明公开的突变酿酒酵母起始转录因子的氨基酸序列为SEQ ID NO：2所示，其转化入酵母菌中可以提高酵母的木糖利用和葡萄糖、木糖共利用的效率。

The dose-dependent experiment revealed that Id1 antagonised E47 and Ets1 mediated transcriptional activation in a dose-dependent manner. With pGL3-870 as a template, site-directed mutagenesis of E-box and / or ETS-binding site was introduced into p16 promoter. E47 could not activate the transcription of p16 promoter with E-boxes mutated, and Ets1 could not activate the transcription of p16 promoter with EBS mutated. The synergy effect between E47 and Ets1 would occur only if the E-boxes and EBS were present. These facts demonstrated that E47 and Ets1 proteins were not recruited to the promoter by binding to other cis-elements or through interaction with other protein factors, however, they bound to DNA directly through respective consensus sequences in p16 promoter.

以pGL3-870为模板，构建了E-box或/和EBS点突变的p16启动子报告基因载体，将野生型和突变型的报告载体分别与pI-E47、pI-Etsl以及pI-E47+pI-Ets1共转染，发现E47和Ets1所诱导的转录激活作用依赖于启动子DNA上存在的各自的特异结合序列，二者的协同作用也只有当两个结合位点都存在时才会发生，说明E47和Ets1不是与其它作用元件或其它蛋白质因子相作用而被招募到该启动子的，它们是通过启动子上各自的特异结合位点与DNA直接结合的。

The main results were as follows: 1.After being radiated with 60 Co-γ, seven types of mutated plants were obtained through morphologic observation on the aftergrowth of the regeneration plantlets. The mutation characters included the purple leaf vein and petiole, the spotted leaf, the strumae leaf, the acerose leaf, the tender stem, the leaf shape variation, and the leaf color variation.

通过60 Co-γ射线诱变处理后的再生植株试管苗阶段的形态学观察，共获包括紫色叶柄、斑叶、瘤状叶片、细长叶片、茎杆细小、叶型变异、叶色变异的7种不同类型的变异植株。

Other contenders were certain mutated members of the Mali Plavac,(a.k.a Plavac Mali), cépage varieties which are mainly grown in the coastal area known as Dalmatia, a province of Croatia recently a part of the former Yugoslavia and located just across the Adriatic sea from the shores of Italian Apulia.

其他参选人的某些突变成员马里普拉瓦茨， cépage品种，其中主要是生长在沿海地区被称为达尔马提亚，一个省，克罗地亚最近的一个部分，前南斯拉夫和位于隔着亚得里亚海，从太平洋东岸意大利

For example, plants can sometimes transmit somatic mutations to their descendants asexually or sexually where flower buds develop in somatically mutated parts of plants.

例如，植物有时将体细胞突变通过无性或有性过程传递给后代，而花芽可能由植物的体细胞变异部分发育。

The number of nuclei in synchronous blastoderm is much fewer than that in wild type group, and the distribution of nuclei was uneven, which indicates that the nuclear division in mutated early embryos was asynchronous and maybe some nuclei undergoes degeneration.

推测HIRA可能影响了染色体的结构和组装，从而影响了细胞周期的进程，导致果蝇早期胚胎细胞核分裂异不正常。

Methods: The expression of mutated P53 gene in human lymphocytes was investigated using flow cytometry.And the micronucleus and sister chromatid exchange tests were studied in vitro.

以正常人外周血淋巴细胞为材料，用流式细胞仪检测环磷酰胺对突变型P53基因表达的影响，同时以微核及姐妹染色单体互换为指标，进行致突变研究。

The chromosome number of the mutated tomato (2n=4x=48) was twice that of the control.

变异材料的细胞染色体(2n=4x=48)为二倍体材料的二倍。

The two-acre Dunbar Community Garden in Little Rock has served as a model for several years.

几年来，坐落于小石城，占地两英亩的邓巴社区菜园树立了一个标杆。

Jerry points to the jacket hanging in the bathroom. It's ruined, and unwearable What?

杰瑞指着洗手间里挂着的夹克，毁了，不能穿了）什么？