查询词典 mediator variable

TGF-βbinds to a heteromeric complex of type I and type II receptors. The constitutively active type II receptor phosphorylates and activates the type I receptor which phosphorylates Smad2 and Smad3 (receptor-associated Smads). Receptor-associated Smads bind the common mediator Smad4 and are translocated to the nucleus, where they associate with DNA-binding cofactors to modulategene transcription.

TGF-β与其效应细胞表面的Ⅱ型受体TβRⅡ和Ⅰ型受体TβRⅠ形成的异源二聚体结合，相继激活TβRⅡ和TβRⅠ，活化的TβRⅠ再进一步活化Smad2和Smad3，磷酸化的Smad2/3必须与Smad4结合形成复合物，才能进入细胞核，调节靶基因的转录[6]。

It was he who revealed to me that my grandfather was not neutral but had been a mediator in the 1928 strike, and he considered hima just man.

就是他向我透露说，在1928年的罢工事件里我外祖父并不是中立派，而是居间斡旋的一分子，并且，他认为我外祖父是一个正直的人。

Methods: the present study improved isolation of LDL, undertook one-step of density gradient centrifugation, generate E-LDL by treatment LDL with multiple enzymes, direct fluorescent label CRP and LDL, and investigate whether CRP play as intermedial mediator in atherosclerosis. Experiment consists of 8 groups: control group, N-LDL group, ox-LDL group, E-LDL group, CRP+N-LDL group, CRP+ox-LDL group, CRP+E-LDL group.

本研究参考文献改进LDL提取方法，通过一次性密度梯度超速离心，分离LDL，并且通过复合酶处理以及铜离子氧化法分别生成E-LDL和ox-LDL，并直接对CRP及LDL进行荧光标记，通过与内皮细胞共孵育，利用荧光显微镜检测CRP及LDL与内皮细胞结合，实验分为8组：空白对照组、CRP组、N-LDL组、ox-LDL组、E-LDL组、CRP+N-LDL组、CRP+ox-LDL组、CRP+E-LDL组。

Human basic fibroblast growth factor is a single-chain heparin-binding polypeptide. It is a general regulatory mediator for different cells such as endothelial cells and for other cells of mesodermal and neuroectodermal origin, it stimulates cells proliferation, inducing or delaying differentiation.

人碱性成纤维细胞生长因子是一种单链的具有与肝素结合能力的多肽分子，它能够调节内皮细胞及其它来源于中胚层和神经外胚层等多种细胞的生长、分化、迁移和凋亡，同时是一种重要的血管生成因子，因此具有广泛的临床应用价值。

The concentration of glucose was detected by cyclic voltammetry via ferrocene monocarboxylic acid as mediator.

以甲酸二茂铁为电子媒介体，用循环伏安法检测GOD电极对葡萄糖的响应。

Studies in animals and humans overthe last four years have provided compelling evidence that leptinmay be a neurohumoral mediator capable of signalling between theextent of nutritional intake and body fat store to the centralnervoussystem.

过去几年在动物和人身上的研究提供了强有力的证据表明：瘦素可能是一种神经体液调质，就营养摄入与脂肪贮存程度向中枢神经系统发出信号。

More importantly, blocking CPT-induced Noxa using specific siRNA significantly reduces the apoptosis response, indicating that Noxa is an essential mediator for CPT-induced apoptosis.

通过免疫共沉淀实验，我们证明了不管有没有CPT处理的情况下Noxa都可以和Mcl-1相互作用，说明Noxa和Mcl-1之间应该存在一个平衡，从而调节细胞凋亡。

An example of such a mediator is pyocyanin (Mavrodi et al., 2001), produced by an isolated Pseudomonas aeruginosa species from the fuel cell.

这样斡旋人的例子是绿脓菌青素(等Mavrodi， 2001)，生产由一个被隔绝的绿浓杆菌种类由燃料电池。

As well as being our Mediator, Jesus is also our Reconciler.

耶稣既是我们的中保，也是我们的救赎者。

A redox mediator is a compound that can be reversibly oxidized or reduced.

一个氧化还原的斡旋人是可以可逆被氧化或减少的化合物。

The statistical analysis of this large set of mutations has led us to propose a diagnostic strategy that should help with the molecular work-up of optic neuropathies.

这一大系列基因突变的统计学分析引导我们提出一个诊断策略，可以帮助我们对视神经病变进行分子学的诊断检查。

The results show that the pipe grouting changes the mechanical parameters of surrounding rocks to achieve the security of engineering objectives by reinforcing surrounding rocks and bolcking the water.

研究表明：小导管注浆一方面改变了围岩的力学参数，另一方面利用浆液的固结特性可以实现堵水和加固围岩的工程目标，使隧道在开挖过程中的安全得到保障。