查询词典 maximum dose

Objective To conduct Pharmacodynamics research of Qianliean pellet and provide the basis for the clinical medication. Methods (1) The influence on the rats with non-bacterial prostatitis of 1.5% carrageenin. Rats were divided randomly into the normal control group, the model control group, the Qianliean low-dose group (1.5 g/kg), mid-dose group (3.0 g/kg), high-dose group (6.0 g/kg), with 10 rats in each group. All groups were treated continuously for 7 days, once a day. The model control group was given distilled water, 30mins after the last medication, injects 1.5% carrageenin 0.05ml in each rat's prostate, after 24hs, behead execute the rats and record the white blood cell number and Lecithin density.

方法(1)对1.5%角叉菜胶致大鼠非细菌性前列腺炎的影响：将大鼠随机分为正常对照组、模型对照组、前列安颗粒小剂量组（1.5 g/kg）、前列安颗粒中剂量组（3.0 g/kg）、前列安颗粒大剂量组（6.0 g/kg）及阳性药前列舒乐颗粒组（2.4 g/kg）6组，每组10只，各给药组大鼠连续灌胃给药7日，每日1次，模型对照组给予等容量蒸馏水，末次给药后30 min，在每鼠前列腺内注入1.5%角叉菜胶0.05 mL，24 h后断头处死大鼠，取致炎前列腺组织，镜下记录白细胞数和卵磷脂小体密度。

Low-dose mercury exposure can significantly change physiological and biochemical indexes of the blood of SD rats and shows a clear dose-response relationship; moreover, low-dose mercury exposure mainly causes anemia of cellule and olig-pigment and damage of liver and kidney of SD rats in various degrees.

低剂量汞暴露对SD大鼠血液生理生化指标有显著影响，且存在明显剂量-效应关系；低剂量汞暴露主要引起SD大鼠小细胞低色素性贫血及不同程度肝、肾损伤。

P ＜ 0. 001 while the organ coefficient of high dose group was much of HSP70 was characterized by greatly increased expression in low dose group while the relative expression of HSP90β was increased in middle and high dose groups.

热应激蛋白70表达改变以低剂量苯并芘染毒组相对表达值明显增高为特征；热应激蛋白90β表达改变为中、高剂量苯并芘染毒组相对表达值升高。

The patients achieved complete remission after induction course would enter the next grouping:the patients,aged 15-45 years, who had suitable donors and transplantation will were assigned to allogeneic stem-cell transplantation,and for the rest,they would be assigned to accept chemotherapy or autologous stem-cell transplantation randomly.CT and ASCT group both received early intensification and consolidation therapy orderly,which contained high-dose methotrexate,intermediate/high-dose cytarabine and high-dose or high-fraction cyclophosphamide,followed by ASCT or re-induction,later consolidation and maintenance chemotherapy for CT group.

符合入组条件的成人非Ph+ALL患者纳入研究，患者接受标准VDCP±L诱导治疗达到完全缓解(complete remission，CR)后进入下一阶段分组研究：年龄≤45岁，有合适供者及移植意愿者接受异基因造血干细胞移植allogeneic stem cell transplantation，Allo-SCT其余患者根据意愿分别接受自体造血干细胞移植(autologous stem cell transplantation，ASCT和化疗Chemotherapy。

Missed dose: skip the missed dose and go back a daily dose. Do not double the doge the next day.

如某天忘记添加本产品，请不要双倍补偿添加，只需要加回每日的正常剂量便可。

METHODS: Total 60 male Wistar rats were randomly divided into 6 groups, i.e., normal control group , DMN model group , large dose treatment group , middle dose treatment group, small dose treatment group and Dongbao gantai treatment group. The liver fibrotic model was induced by i.p. dimethylnitrosamine for 4wk. The relative herbs were given after model establishment in each treatment group and the administration lasted for 6 weeks. Decollate to get the blood and The serum hepatofibrosis indexes, hyaluronic acid, collagen IV, pro-collagen type III and laminin were measuredwith radioimmunoassay. SOD and MDA were measured with biochemistry method. The liver pathological changes were observed in each group of rats.

将60只雄性Wistar大鼠随即机分正常对照组、模型对照组、实验大剂量组(20ml/kg/d)、实验中剂量组(10ml/kg/d)、实验小剂量组(5ml/kg/d)及东宝肝泰药物对照组；腹腔注射二甲基亚硝胺制备大鼠肝纤维化模型，连续灌胃6周，断头取血，生化检测血清SOD、MDA；放射免疫法测定血清HA、LN、PCIII及IV-C；取肝左叶做HE染色和Mallory胶原染色，观察肝病理组织学改变。

Methods The cardiac myocytes model of myocardial ischemia reperfusion injury was induced with sodium dithionite (Na2S2O4). The primary cultured cardiac myocytes of SD neonatal rats were randomized into six groups: normal group, model control group, high-dose β-asarone (25 μg/mL), middle-dose β-asarone group (12.5 μg/mL), low-dose β-asarone group (6.25 μg/mL) and medium group.

采用连二亚硫酸钠(Na2S2O4)建立心肌细胞MIRI模型，将原代培养的SD大鼠乳鼠心肌细胞分6组：正常对照组、MIRI模型组、β-细辛醚高、中、低剂量组(25， 12.5， 6.25μg/mL)、基质组。

Methods Animals were randomly and equally divided into five groups: saline control group, positive drug control group, low-dose, medium-dose and high-dose crocetin group. Animals were anesthetized with urethane (1.2 g/kg), then followed by the perfusion of aconitine (10 μg/mL) through caudal vein in rats, or of ouabain (9 μg/mL) through external jugular vain in guinea pigs in a constant velocity of 0.1 mL/min, and the emergence time of ventricular fibrillation, ventricular extrasystole, ventricular tachycanlia and cardiac arrest were then detected and recorded. The recorded time was then translated to the cumulated amount of aconitine and ouabain. Experimental arrhythmia was induced by rapid injection of 4% CaCl2 (140 mg/kg), and the emergence time, persistence time, incidence and death of arrhythmia after the administration were observed.

将实验动物随机分为生理盐水组，阳性药物对照组，藏红花酸高、中、低剂量组，SD大鼠采用1.2 g/kg乌拉坦麻醉后，从尾静脉匀速(0.1 ml/min)灌注10μg/ml乌头碱溶液，豚鼠麻醉后从颈静脉匀速(0.1 ml/min)灌注9μg/ml哇巴因溶液，观察出现室性期前收缩、室性心动过速、室颤和心脏停搏的时间，然后换算成乌头碱和哇巴因的累积量；快速推注4%氯化钙(140 mg/kg)诱导大鼠心律失常，观察给药后心律失常出现时间、持续时间、心律失常发生数及死亡数。

The energy distribution of the focused laser spot has Gaussian profile, and if the exposure dose threshold of the photoresist is less than and far away from the peak of that Gaussian curve, the linewidth will be less affected by the variation of exposure dose or exposure dose threshold, and so, will improve the linewidth stability.

准直光束经物镜会聚后光斑的能量呈近似高斯分布，当胶层的曝光量阈值远离高斯型曝光量曲线的头部时，可以弱化线宽对实际曝光量或胶层曝光量阈值等变化的敏感度，从而提高线宽的稳定度。

Objective To study the effect of helical CT scanning dose and slice thickness on lung density, and to determine whether the lung density value measured by standard dose helical CT scan can be used for low dose helical CT scan.

目的 探讨螺旋CT扫描剂量、层厚是否对肺密度有影响，以决定常规剂量螺旋CT扫描测得的肺密度值能否适用于低剂量螺旋CT。

The French are not suggesting a new EU treaty, but they have plenty of other wheezes.

法国人并不是在建议签署一个新的欧盟条约，但他们有许多其他的阴谋。

This letter was written by my brother.

这封信是我弟弟写的。