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Itis a great deal of assistment for treatment and prognosis of patients, if we candiagnose hepatic fibrosis in forepart. The aim of this experiment evaluate the dignosisvalue of ultrasound elastic imaging on early hepatic fibrosis.we will supply thefundermental data for reseach henceforth. 2、Materials and MethodThe number of Wister rats is 30 and weight is 180-220g. 30 Wister rats had beenligated on the right hepatic ducts (include middle lobe、right lobe and caudate lobe) tocause partial cholestatic hepafibrosis factitiously and divided in A, B and C groups. Aand B groups had been ligated on the right hepatic ducts both. The different with Aand B is that the time of A group after ligation on the hepatic ducts is 2 weeks and thetime of B group is 1 week.

将实验动物分为A、B、C三组,A组为结扎大鼠右侧胆管(包括中叶、右叶、尾状叶)2周后进行检查。B组为结扎大鼠右侧胆管1周后进行检查,C组行假手术为对照组。A组大鼠麻醉后,腹部备皮,皮肤常规消毒,腹部横行切开,暴露肝脏、胆总管,游离右侧胆管,结扎,然后关腹;C组,仅开腹然后关腹,即假手术组。A、C两组同批实施手术,A、C两组术后1周,B组实施手术,步骤、方法、部位同A组。

In patients with CPS but without GTS, the focus was mostly located in unilateral temporal lobe, esp, in the medial temporal lobe or the limbic system if the ictal and the interictal EEG was normal, but in those patients with CPS and GTS, the focus was located in the lateral temporal parietal lobe or temporal parietal-occipital areas.

CPS不继发全身性发作的患者,病灶多局限于一侧颞叶,如发作期和发作间期脑电图均正常,更应考虑病灶位于颞叶内侧面,或边缘系统;CPS继发GS的患者病灶多位于颞叶外侧面与顶、枕交界区。

The pituitary gland consisted of neurohypophysis and adenohypophysis. The adenohypophysis was divided into anterior lobe, intermediate lobe and posterior lobe.

黄颡鱼的脑垂体由垂体神经部和垂体腺部组成,垂体腺部又由前叶、间叶和后叶三部分构成。

The patient showed atrophy in frontal and temporal lobe on regular MRI, significantly reduced amount of Nacetyl aspartic acid、cholineand creatinecompared with contralateral on MRS , remarkably decreased blood flow in the left temporal polar and front part of fontal lobe compared with contralateral on PWI. There were decreased association fibers between Broca and other regions meanwhile no association fibers were found between triangular area and wernicke region on DTI. The fibers projecting to opercular part of frontal lobe via archiform fibers were lessened. The mean FA and fibers of Broca and Wernick regions were less than that of the healthy subjects.

常规MRI显示左侧额叶及颞叶萎缩;磁共振波谱分析显示左侧颞叶和额叶N乙酰天门冬氨酸、胆碱、肌酸含量较对侧明显减低;磁共振灌注成像显示左侧颞极及额前部的血流量较对侧减低;弥散张量成像显示左Broca区与其他脑区间纤维联系减少,三角区与Wernicke区无纤维联络,左侧Wernicke区通过弓状纤维到达额叶岛盖部的纤维减少,Broca及Wernicke区平均FA及纤维束较正常人减少。

The opioid receptors mainly distribute at prefrontal lobe(obitofrontal gyrus, medial superior frontal gyrus, superior frontal gyrus), paralimbic cortices (cingulated cortex and hippocampus), insular cortex、pallidum and the opercular section of frontal lobe and parietal lobe. These results corresponded with the classic theories on PET neurorecepotors imaging.

通过phfMRI方法进一步验证了人脑中枢系统内阿片受体的主要分布区,其中皮层区集中在前额叶(眶额皮质、额上回、额内上回)、边缘系统、颞叶脑岛区及额顶叶的岛盖部;皮层下区集中在苍白球区;小脑集中在小脑皮层、小脑脚及小脑蚓部。

The main cortical activation areas lies in : obitofrontal gyrus, medial superior frontal gyrus, superior frontal gyrus, the opercular section of frontal lobe and parietal lobe, anterior and middle cingulated cortex, insula cortex, hippocampus, parahippocampal gyrus, precuneus, middle temporal gyrus, inferior temporal gyrus, occipital lobe.

本组实验药物作用于受体分布的相关激活脑区主要位于:⑴皮层区:额叶(眶额回、额内上回、额上回)、颞叶、顶叶、边缘系统(扣带前回、扣带中回、海马、海马旁回)等。

The decreased ReHo is distributed over left occipital lobe, left cuneus, left precuneus, left lingual gyrus and right frontal lobe, right middle frontal, right gyrus, right frontal Lobe, right inferior frontal gyrus and right precuneus.

ReHo增高的脑区广泛分布于左侧枕叶、楔叶、楔前叶、右额叶、中心前回、额下回、左侧的舌回和右侧顶叶。

The results of respiratory mechanics, homodynamic mechanics,aterial blood gaS, and inflaInInatory factors [TNF- Q, IL-l fl, IL-6,IL-l0, and adrenomedulin] which detected in animal serumand bronchial alveolar lavage fluid obtained from tiP lObe,heart lobe, and diaPhragIn lobe of right lung seParate1y in the mongreldogs were measured before and after lung injury (including receivinglung protective ventilation).

本实验证明了 loS肺内/肺外不同源性 ARDS动物模型的差异性,而且AnDS的肺部病变存在不均一性和多形性的特点,对有关ARDS进行性低氧血症的发生机制提出了肺动静脉可能存在类似于右一左分流的肺内分流现象,以及因肺内分流而导致严重通气/血流比例失调的解释。发现小潮气十PEEP通气对肺内源性 ARDS疗效不佳,而俯卧位+小潮气-I- PEEP通气对肺内/肺外不同源性ARDS均有较好的疗效。。

Methods The solid sections of hepatic segments were obtained by liver incision according to the lines of surface projections of each hepatic fissures The structural landmarks were on lines of section which were observed Results There existed the structural landmarks on the solid sections of median fissure,right interlobar,right anterior lobe,right posterior liver lobe and left hepatic lobe fissures They were showed on the solid images of three dimensional ultrasound.

所谓三维超声立体断层图是指在同一幅超声图像中,同时显示器官或病灶的冠状面和矢状面,或者同时显示冠状面和水平面,或者同时显示矢状面和水平面,构成&蛋糕块&状的立体图像 [1] ,而不是凸凹不平的&立体感觉&。

ResultsIdiopathic nocturnal frontal lobe epilepsy has distinctive clinical seizure characteristics. The onset age is younger than 20 and the ratio of male cases to female cases is 2 to 1. The most notable clinical characteristics are nocturnal clustered postural or dystonic seizures and complex motor activities, with 14% of the patients have epileptic family history. The interictal routine EEG of 22.9% and active EEG of 28% cases in wakeness and 38% cases in sleep showed frontal lobe epileptiform discharge while the ictal EEG of 66.7% cases showed frontal lobe epileptiform discharge. Drug therapy is effective in 80% cases with 30% completely controlled.

结果 特发性夜间额叶癫痫具有特征性的临床发作特点,大多数于20岁之前起病,男女比例2:1,以夜间成串的偏转性、姿势性强直及过度运动发作为最显著的临床特征。14%有阳性癫痫家族史。22.9%清醒发作间期常规脑电图及28%清醒发作间期动态脑电图可见额叶癫痫样放电,38%患者的睡眠发作间期动态脑电图可见额叶癫痫样放电,66.7%患者的发作期脑电图可见额叶癫痫样放电。80%药物治疗有效,30%可完全控制。

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