查询词典 insulin

Objective To investigate the impact of insulin resistance and insulin secretion on the development of glucose intolerance in Chinese.

目的研究胰岛素抵抗和胰岛素分泌缺陷与中国人糖耐量变化的关系。

The comparisons of biochemistry between OP and OR rats The differences between OP and OR rats included not only body weight, but lipids metabolism and insulin sensitivity as well, characterized with insulin resistance, increasing in serum free fatty acids and ketone body, and hepatic TC and TG in OP rats. However, no significant differences were observed in serum TG, TC, LDL, HDL and fasting glucose between OP and OR rats.⑶Comparisons of metabolites in serum, urine and liver tissue between OP and OR rats①There were significant differences in amino acids concentration between OP and OR rats,especially in liver tissue, such as high concentrations in ketogenic and glucogenic amino acids in OP rats, suggesting differences in amino acids metabolism;② The different metabolites between OP and OR rats included increasing of various saturated fatty acids and decreasing of polyunsaturated fatty acids in OP rats;③The urinary metabolites analysis indicated that different structure or metabolism of gut microflora might exist between the two phenotypes, which probably influenced the regulation of body weight gain;④The end-products of catecholamines in urine and intermediates of krebs cycle in serum in OP rats were all up-regulated, suggesting that the activity of sympatheic nervous system and energy metabolism was higher in OP rats than OR rats.

胰岛素耐受实验和胰岛素敏感指数表明OP动物的胰岛素敏感性较OR动物下降，而OP大鼠血清中游离脂肪酸、酮体、肝脏总胆固醇和甘油三酯水平显著升高；但是，OP与OR大鼠血清中总胆固醇、甘油三酯、低密度脂蛋白、高密度脂蛋白和空腹血糖等的水平并无显著性差异；⑶肥胖易感与肥胖抵抗大鼠血清、尿液和肝脏组织提取物中代谢物的比较研究表明：①OP与OR大鼠的血清、尿液和肝组织提取物中多种氨基酸的含量存在显著差异，并以肝组织中的差异氨基酸数量为最多，包括各种生酮和生糖氨基酸水平在OP组的升高，说明氨基酸代谢的差异是两种体重表型大鼠之间存在的重要差异特征之一；②OP与OR动物肝脏和血清差异代谢物中包含多种饱和长链脂肪酸的升高如十四烷酸、十六烷酸、硬脂酸等和多不饱和脂肪酸的下降如亚油酸和花生四烯酸，说明两种体重表型动物的肝脏脂肪酸代谢存在明显差异；③长期高脂饮食喂养后，动物的尿液代谢物分析表明OP与OR动物体内的肠道菌群结构存在差异，这些菌群上的差别可能在动物体重增长的调节上产生影响；④与OR动物相比，OP动物尿液代谢物中儿茶酚胺类递质的代谢终产物如高香草酸、扁桃酸和4-羟基苯乙酸明显升高。

KEY WORDS ginseng fruit saponins; insulin resistance; insulin sensitivity index

关键词］人参果总皂苷；胰岛素抵抗；胰岛素敏感指数

Investigation of the insulin-like growth factor system in breast muscle during development in Langshan and Arbor Acres chickensWe analyzed the effects of nutrient availability on the breast muscle insulin-like growth factor system.

本研究揭示了在生长轴、甲状腺轴和肾上腺轴中某些基因在特定时期在转录水平上的表达是相关的，并且发现下丘脑、垂体和肝脏中某些基因在品种间的表达差异是受营养因素调控影响的。2。

In order to research the synergistic effect of glucose of insulin on lipogenesis in goose liver, we measured the effect of glucose of insulin on triglycerides accumulation, enzyme activity and mRNA expression of fatty acid synthase in primary hepatocytes of Sichuan White Goose and Landes Goose.

为了研究胰岛素和葡萄糖对鹅肝细胞内脂肪酸生成的协同作用，我们通过培养四川白鹅和朗德鹅原代肝细胞测定葡萄糖和胰岛素对其TG含量，FAS活性及基因表达的影响。

METHODS: The [B9Glu, B10Asp] insulin (E,D-insulin) receptor binding activity, glucose uptake activity, and lipogenesis activity were measured in isolated adipocytes.

在分离的大鼠脂肪细胞中测定[B9Glu，B10Asp]胰岛素的受体结合活性、葡萄糖吸收活性和脂生成活性。

To define the role of insulin action in the central nerous system in regulating the counterregulatory response to hypoglycemia, mice with a brain/neuron-specific insulin receptor knockout and littermate controls were subjected to 90-min hyperinsulinemic (20 mU · kg–1 · min–1)-hypoglycemic (1.5 mmol/l) clamps.

为了证实中枢神经系统的胰岛素在低血糖反应的调节作用，对中枢神经胰岛素受体敲除的小鼠和对照组小鼠进行了高胰岛素（20 mU · kg–1 · min–1）-低血糖(1.5 mmol/l)的钳夹试验。

Melton and colleagues used a virus to turn on three genes in the mouse pancreas and found that some cells that do not normally produce insulin transformed into cells that do produce insulin.

梅尔顿及其同事们利用病毒把小鼠胰腺中的三种基因激活，发现某些通常不产生胰岛素的细胞转变成产生胰岛素的细胞。

to investigate the dependence of insulin sensitivity index and glucose effectiveness on the insulin kinetics parameters by using minimal model.

研究用最小模型法估计的胰岛素敏感性指数和葡萄糖利用效能是否强烈依赖于胰岛素动力学模型参数的变化。

"I have over 225 patients who have been on inhaled Exubera, Novo Nordisk and Mannkind insulin, and my clinical experience is that inhaled and injectable insulin can be interchanged without problem," Dr. Norwood said.

诺伍德医生说：我有超过225名患者在使用吸入性胰岛素，诺和诺德公司以及Mannkind 公司的胰岛素，我的临床经验就是吸入性胰岛素和注射性胰岛素可以互换而不会有问题。

For you say, My doctrine is pure, And I am clean in Your eyes.

11：4 你说，我的道理纯净，我在你眼前清洁。

The method takes make water sedimentary in patient of be in hospital of leucocyte grow in quantity 30, according to clean middle make water bacterioscopy result, distinguish the patient to affect group and blame infection group, pathology of puncture of farther travel kidney analyses blame infection form.

方法取尿沉渣中白细胞增多住院患者30例，根据清洁中段尿细菌检查结果，将患者区分为感染组和非感染组，非感染组进一步行肾穿刺病理分析。