查询词典 insulin

RESULTS: Biomaterial vector which were used to coated insulin could prevent insulin degradation by erepsin and enhance insulin stability. In addition, biomaterial vector benefited for uptake and transport of intestinal tract mucosa to insulin, target-control of drug release, enhancement of drug bioavailability, and establishment of insulin release velocity style for human physiological drive so as to realize sustained release of insulin.

结果：以生物材料作为载体包埋胰岛素，可避免胰岛素被胃肠蛋白酶降解，提高其在胃肠道内的稳定性，并有利于肠道黏膜对胰岛素的摄取和转运，在人体内递药过程中又能实现靶向控制药物释放，提高药物的生物利用度，满足人体生理需求的胰岛素的释放速率模式，实现了胰岛素的持续释放。

The results showed as:(1)Gegen decreases fasting insulin and insulin resistance index and increases insulin sensitive index of rats of insulin resistance induced by dexamethasone significantly;(2)Gegen can improve glucose tolerance of rats of insulin resistance but not to alloxan indued diabetes mice;(3)Gegen increases glucose intake of 3T3-L1 adipocytes and improves the insulin resistance of 3T3-L1 adipocytes induced by dexamethasone significantly;(4)Gegen can activate peroxisome proliferator- activated receptor gamma, make it bind to PPAR response elements;(5)Gegen can up-regulate mRNA expression of PPAR v ,aP2 and adiponectin.

结果表明：①葛根显著降低地塞米松诱导的胰岛素抵抗大鼠血清胰岛素水平和胰岛素抵抗指数，升高胰岛素敏感指数，改善大鼠的胰岛素抵抗；②葛根显著改善胰岛素抵抗大鼠的糖耐量，但对四氧嘧啶糖尿病小鼠的糖耐量没有明显的作用；③葛根显著增加胰岛素抵抗3T3-L1脂肪细胞对葡萄糖的摄取，改善地塞米松诱导的3T3-L1脂肪细胞的胰岛素抵抗；④葛根能促进HepG2肝癌细胞过氧化物酶体增殖物激活受体γ与靶基因的特异DNA序列结合，对PPARγ及其下游基因的转录具有激活作用；⑤葛根能够促进PPARγ及其下游基因脂肪酸结合蛋白(aP2)、脂联素mRNA的表达。

We determine model rat FBG,fasting insulin,sugar tolerance,insulin tolerance,insulin sensitivity index,and insulin resistance index,lipid metabolism and free fatty acids content of serum and hepatic,HE staining of pancreas,to observe the effects of Huang Qi San on glycolipid metabolism and insulin resistance in T2DM-IR.

黄芪散干预实验性2型糖尿病胰岛素抵抗的作用及机制研究通过建立STZ所致DM小鼠模型、氢化可的松琥珀酸钠诱导的IR小鼠模型初步评价黄芪散对DM及IR的干预作用。

All methods of insulin administration were recorded: insulin drip, insulin in the PN and long-acting subcutaneous insulin.

所有方法使用的胰岛素均需记录，包括滴注的胰岛素，PN中的胰岛素和长效皮下注射的胰岛素。

Because of the development of micro-computer chip , insulin-conditioning replaced by mechanical computer-controlled screw propeller chip device, will enable the regulation of insulin infusion rate of increase is more accurate, because the concentration of regular insulin have been enhanced to 100U/ml, so that micro-insulin pump in the practical application of more extensive .

由于微型电脑芯片的发展，胰岛素调节装置由机械式改为电脑芯片控制的螺旋推进装置，可使胰岛素输注增幅调节更加精确，由于正规胰岛素浓度已提高到100U/ml，使胰岛素泵的微型化在实际应用中更加广泛。

Prehypertensive subjects versus normotensive subjects had significantly higher body mass index and subscapular skinfold, systolic and diastolic blood pressures, and triglycerides beginning in childhood; higher glucose in adolescence; and higher low-density lipoprotein cholesterol, fasting insulin, and insulin resistance index in adulthood. Hypertensive subjects versus normotensive subjects had higher adiposity measures, SBP and DBP, glucose, and triglycerides beginning in childhood; higher insulin and insulin resistant index in childhood and adulthood; and lower high-density lipoprotein, cholesterol in adulthood.

与正常血压者相比，高血压前期者其幼年期基础体重指数、肩胛下皮肤皱褶厚度、收缩压和舒张压、甘油三脂等指标更高；在青春期血糖水平更高；在成年期低密度脂蛋白胆固醇、空腹胰岛素、胰岛素抵抗指数更高；与正常血压者相比，高血压者在幼年时基础水平的肥胖积分、SBP 和DBP、血糖、甘油三脂等更高；在幼年期和成年期胰岛素和胰岛素抵抗指数水平均更高；在成年期高密度脂蛋白胆固醇水平更低。

Homeostasis model assessment insulin resistance=fasting plasma glucose×fasting insulin/22.5,homeostasis model assessment insulin aeschynomenous index=1/,index of insulin increment to gluncose increment at 30 min(△I_30/△G_30)=(I_30-I_0)/(G_30-G_0)post oral glucose,a...

采用稳态模型评估法计算胰岛素抵抗指数，胰岛素敏感指数，胰岛素分泌指数，服葡萄糖后30 min胰岛素增值与血糖增值的比值(ΔI30/ΔG30)、胰岛素曲线下面积。

Compared with these of fat-fed group,the body weight,blood glucose levels after oral glucose and the glucose area under curve,40min and 90min blood glucose levels after insulin injection subcutaneously and the glucose area under curve in the insulin tolerance test,the fasting serum insulin,insulin resistance index,serum cholesterol,triglyceride and lower density lipoprotein cholesterol decreased.

n-6脂肪酸组从第1~10周体重均较高脂组明显减轻，糖负荷后血糖和糖耐量试验中葡萄糖曲线下面积、皮下注射胰岛素后40 min9、0 min血糖及胰岛素耐量试验中葡萄糖曲线下面积、血清胰岛素、胰岛素抵抗指数、血清胆固醇、甘油三酯和低密度脂蛋白含量均较高脂组明显降低

Compared with these of fat-fed group, the body weight, blood glucose levels after oral glucose and the glucose area under curve, 40min and 90min blood glucose levels after insulin injection subcutaneously and the glucose area under curve in the insulin tolerance test, the fasting serum insulin, insulin resistance index, serum cholesterol, triglyceride and lower density lipoprotein cholesterol decreased, the fasting serum leptin, high density lipoprotein cholesterol and C18:2 were significantly increased in N-6 PUFAs group.

n-6脂肪酸组从第1~10周体重均较高脂组明显减轻，糖负荷后血糖和糖耐量试验中葡萄糖曲线下面积、皮下注射胰岛素后40min、90min血糖及胰岛素耐量试验中葡萄糖曲线下面积、血清胰岛素、胰岛素抵抗指数、血清胆固醇、甘油三酯和低密度脂蛋白含量均较高脂组明显降低；血清瘦素水平、高密度脂蛋白、18碳2烯酸较高脂组明显升高。

"Working with mice, we found that glucose levels were elevated and there was glucose production from a 'precursor', a source not normally metabolised."Other results in the study show that to some extent ARNT is regulated by insulin, so that insulin resistance in itself will contribute to a decrease in ARNT. If liver cells are treated with insulin, there will be a small increase in ARNT protein. The insulin will also help move the ARNT into the nucleus of the cell, where it does its job as a master regulator.

胰岛素绝对或相对不足时，肝脏内一种称之为 ARNT 的转录因子减少达90%，而 ARNT 与控制肝脏生产和释放葡萄糖的基因表达有关， ARNT 减少，肝脏生产和释放葡萄糖增加。2型糖尿病时，胰岛素相对不足不仅使肝脏内 ARNT 减少，也导致胰岛β细胞内 ARNT 减少，使得胰岛素生成减少和释放延迟。

Pradeep Indulkar, a senior official at the Maharashtra state Home Ministry say 101 human were killed and 287 injured.

马哈拉施特拉邦内政部高级官员Pradeep Indulkar称，有101人在冲突中丧生，287人受伤。

Mark Frei, a senior vice president of West, says 80% of West's homeagents have some college education, compared with 30% of those whowork in office-based call centers.

Frei说，该公司80%在家办公的人员都拥有本科学位，而在公司电话中心工作的人中只有30%拥有本科学位。