查询词典 inhibited factor

Results: 1 The capacity of engulfment of A549 cells started enhancing at the 1h of preincubation with dexamethasone, reached the highest at the 4h of preincubation,At the 8h、24h of preincubation the capacity of engulfment evidently reduced. 2 Glucocorticoid cytosolic receptors antagonist RU38486 inhibited the improved engulfment ability by dexamethasone. 3Phagocytosing apoptotic eosinophils did not change the release of IL-6 and IL-8,but can inhibited the release of IL-6 and IL-8 from A549 cells stimulated by lipopolysaccharide. 4Increasely uptaking by dexamethasone also did not agitate the release of IL-6 and IL-8 from A549 cells. Conclusion: 1Dexamethasome improve the phagocyte capacity for apoptotic eosinophils of A549 cells by glucocorticoid cytosolic receptors, and the effect presents time-dependently. 2Phagocytosis of apoptotic eosinphils can degrade inflammatory reflection, so it is likely to be critical in the control of asthma inflammation.

结果： 1 A549细胞在地塞米松诱导后1小时吞噬能力开始升高，4小时吞噬能力达最高峰，8小时、24小时吞噬能力明显下降 2加入RU38486后抑制了地塞米松所增强的吞噬能力 3凋亡嗜酸粒细胞的吞噬并不能改变A549细胞释放IL-6和IL-8，但能抑制脂多糖刺激A549细胞后IL-6、IL-8的分泌 4地塞米松增加的吞噬也不激发A549细胞释放IL-6和IL-8 结论： 1地塞米松促进A549细胞吞噬凋亡的嗜酸粒细胞是通过A549细胞糖皮质激素胞浆受体发挥作用的，并且具有时间依赖性 2 A549细胞吞噬凋亡的嗜酸粒细胞能降低炎症反应，对哮喘炎症的控制具有重要意义

The bioactive screening on aldose reductase, nitric oxide synthetase, liver cancer Bel-7402, cavum oris epithelioma KB and colon cancer HCT-8 showed that paeoniflorin inhibited the nitric oxide synthetase by the rate of 83. 4% at the concentration of 5μg/ml, and paeoniflorigenone inhibited the colon cancer HCT-8 cells by the rate of 83. 2% at the concentration of 5μg/ml.

通过醛糖还原酶、NO合酶、肝癌Bel-7402、口腔上皮癌KB以及结肠癌HCT-8五种模型的生物活性筛选表明，在51μg／ml的浓度下，芍药甙对NO合酶的抑制率达83.4％，芍药甙元对结肠癌HCT-8细胞株的抑制率达83.2％，有较好的抑制作用。

Results: It showed that esculin, demethylfuropinarine, decursin and columbianadin inhibited growth of human carcinoma cell line KB cell and their activity showed doseeffect relationship; and umbelliferone renecioate, sphondin and coumestrol inhibited growth of human leukemia cell line HL60 cell and their activity showed doseeffect relationship.

结果：马栗树皮苷、去甲基呋喃皮纳灵、前胡素和二氢山芹醇当归酸酯对人鼻咽癌细胞株KB细胞的生长有一定程度的抑制作用，且呈浓度-效应关系；伞形花内酯刘寄奴酸酯、牛防风素和考迈斯托醇对人白血病细胞株HL-60细胞的生长有一定程度的抑制作用。

Esculin, demethylfuropinarine, decursin and columbianadin inhibited growth of human carcinoma cell line KB cell. Umbelliferone renecioate, sphondin and coumestrol inhibited growth of human leukemia cell line HL60 cell.

马栗树皮苷、去甲基呋喃皮纳灵、前胡素和二氢山芹醇当归酸酯对人鼻咽癌细胞株KB细胞的生长有抑制作用；伞形花内酯刘寄奴酸酯、牛防风素和考迈斯托醇对人白血病细胞株HL-60细胞的生长有抑制作用。

The results indicate that, during the early storage period under short time treatment with heat air, the activities of amylase and polygalactouronase are effectively decreased; starch content reduction is inhibited; the degradation speed of pectin and the decrease speed of flesh hardness are slowed down, and the release rate of ethylene in fruit is decreased. During the later storage period, the decomposition rate of middle lamella and primary wall of the Li jujube fruit treated with heat air for a short time is delayed, exosmosis of cell contents is inhibited, and the cell structure is protected, so the storage time of Li jujube fruit is prolonged.

结果表明，梨枣采后贮前短时间热处理能有效地降低早期淀粉酶和多聚半乳糖醛酸酶活性，抑制淀粉水解，延缓果胶降解，降低乙烯释放量，延缓果肉硬度下降速度，后期能延缓果肉细胞中胶层和初生壁分解，阻止细胞内含物外渗，保护细胞的结构，从而延长了贮藏保鲜期。

In this study,we focus on the interaction between nuclear modifier gene MTO2 and aminoglycosides,and have received the following innovations.1,We here report first that the knockout of MTO2 significantly inhibited mtDNA p_(454)~R mutant's sensitivity to aminoglycoside antibiotics.Here are the results:(1)In neomycin GYP medium,when mitochondria genes were wild type,whether MTO2 knockout or not,the growth of yeast strains has no significant difference;when mitochondria genes were complete deletion,whether MTO2 knockout or not,the growth of yeast strains also has no significant difference;Interesting,when mtDNA P_(454)~R,wild-type MTO2 strains were hardly survival in neomycin GYP medium,but the growth of MTO2 knockout strains were only partly inhibited,there was a significant difference performance of neomycin sensitivity between them.

具体结果如下：(1)在含有新霉素的葡萄糖培养基上，mtDNA为野生型、MTO2敲除与否，相应的酵母菌株的生长没有显著差异；mtDNA完全缺失、MTO2敲除与否，相应的酵母菌株的生长也没有显著差异；然而，当mtDNA存在P_(454)~R突变时，MTO2野生型菌株几乎完全不能生长，而MTO2敲除菌株的生长只受到部分抑制，表现二者对新霉素的敏感性存在显著差异。

The results indicated that the inhibited concentrations of kanamycin of adventitious bud formation of Helianthus annus were 75 mg/L and 100 mg/L, when the carbenicillin was used in the transformation procedure; the concentrations was 300 mg/L when the growth of agrobacterium could be effectively inhibited. At the same time, the induction and growth of adventitious bud were not remarkably injured.

在以卡那霉素为抗性选择标记时，对油葵不定芽起完全抑制作用的Km临界浓度在75~100 mg/L；在以羧节青霉素为抑菌剂用于油葵遗传转化试验时，其浓度为300 mg/L时即可有效抑制农杆菌的生长，同时又不会对不定芽的诱导及生长产生明显的伤害作用。

Results:Whith the time and doses of ART incubation extended, ART significantly inhibited the proliferation of SGC-7901 cells and the inhibited effect shows dose-and -time-dependent. Obvious changes of apoptotic morphology were observed by invert microscope, fluorescence microscope, scanning electron microscope and transmission electron microscope, they showed that cells had marked nuclear condensation or the fragmentation of chromation as well as apoptotic , mitochondrial edema and vesicle , with the time of incubation extended , the proliferation rate become slow and the volume became small and transformed. FCM assay indicated that most of the cells were arrested in Go/Gi and the apoptotic peak appeared. During the prolong of incubation time, the apoptosis rate was increased. At the same time, the number of S and G2/M phase cells were decreased. The result of TUNEL indicant that there are apoptosis and necrosis.

结果：随着药物浓度的增加和作用时间的延长，蒿甲醚对胃癌SGC-7901细胞的抑制作用呈时间和浓度依赖关系：在倒置显微镜、荧光显微镜、扫描电镜和透射电镜下可观察到典型的凋亡细胞的形态改变，表现为：核固缩或染色质边聚或凝聚成大块状，可见凋亡小体，线粒体肿胀增殖，严重的空泡化，随作用时间的延长，细胞增殖速度减慢，细胞体积缩小变形；流式细胞术显示胃癌SGC-7901细胞出现明显的凋亡峰，随着作用时间的延长，其凋亡率逐渐升高，细胞周期阻滞在G_0/G_1期，S及G_2/M期细胞数大量减少；流式细胞术TUNEL检测结果显示细胞凋亡和坏死同时存在。

Then, the experiment that edelfosine inhibited the phosphatization of Spm1 was carried out in order to elucidate whether edelfosine affect on the phosphatization of Spm1 induced via Mid2 and inhibited via Pmp1.(1)、On the inhibition experiment of parallel growth of S. pombe wild-type cells, spm1 mutants, pmp1 mutants, mid2 mutants and relevant retransform strains, the spm1 mutants grew well treated with 5.0μM and 10.0μM edelfosine for 24 h; the growth ratio of spm1 mutants had a statistic significance in between the cells previously mentioned and the S.

(1)、通过野生型粟酒裂殖酵母和胞质分裂突变体spm1Δ、pmp1Δ、mid2Δ及其再转化株对依地福新的平行生长抵抗试验，进一步确定依地福新对spm1、pmp1、mid2基因的影响；(2)、应用依地福新对Spm1磷酸化的影响试验，阐明依地福新是否通过影响Mid2蛋白和Pmp1蛋白的表达而影响Spm1蛋白的磷酸化。

After 48h exposure, The GST activities were all inhibited under the exposure of phenol and pyrocatechol, but the GST activities were induced at first and then inhibited under the exposure of resorcinol.

处理48h后，体内GST活力随苯酚和邻苯二酚浓度的升高逐渐降低，而间苯二酚对GST活力的影响与处理24h后GST活力的变化趋势相似。

Warden: That's a beautiful dog, but don't bring her again.

那是条漂亮的狗，但是不要再把她带来了。

You get up in the morning – no hangover!

你第二天早上起来的时候—不会宿醉！