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One way by which IKK- controls skeletal and craniofacial morphogenesis is by repressing expression of fibroblast growth factor family members, such as FGF8, whose expression is specifically elevated in the limb bud ectoderm of IKK--deficient mice.

IKK控制骨骼和颅面形态发生的一个途径是抑制成纤维细胞生长因子家族成员如FGF8的表达，后者的表达在IKK缺失小鼠肢芽外胚层中特异升高。

Objective To investigate the expression of nestin, a type Ⅵ intermediate filament protein in the glomeruli with foot process effacement and the potential relationship between nestin expression in the kidney and the degree of proteinuria.

目的 观察中间丝蛋白类的巢蛋白在足突广泛融合的肾小球中的表达及其与足突病变动态过程和蛋白尿产生的关系。

EFFECT OF EMETINE ON THE EXPRESSION OF P53 IN HUMAN BREAST CANCER CELLS Objective: To determine if the expression of P53 gene is influenced by Emetine that inhibited the NMD mechanism in human breast cancer cells.

中文摘要：目的：探讨依米丁抑制乳腺癌细胞中的NMD机制对P53基因表达水平的影响。

Objective To observe the effect of Shenghui Keli on AD encephalon neural degeneration induced by A β(β-Amyloid protein) from neural function, biochemical and gene expression. Research the degeneration related to apoptosis of cell and gene expression correlate to apoptosis. Then investigate the mechanisms of Shenghui keli treating AD .

目的 从神经功能形态、生化与基因表达等方面，观察生慧颗粒对β-淀粉样蛋白(β-Amyloid protein，Aβ)诱导脑神经细胞变性的干预作用，以及与细胞凋亡、凋亡相关基因表达的关系，探讨生慧颗粒治疗Alzheimer病的作用机制。

By action on HNF3β,HNF6 play some role in endoblast differentiation.Reverse transcription PCR can detect HNF6 gene expression in all tissues. Western blot can detect HNF6 protein expression in all tissues.

本研究结合免疫组织化学、逆转录PCR和Western杂交技术，分别在基因和蛋白质水平上初步探索了转录因子FOXF1、Notch2和HNF6在人类肝癌中的表达规律。

To determine whether the same molecular mechanisms are inoled in the formation process, the expression pattern of transcription factors regulating endoderm and gut deelopment in the mouse embryo was examined by in situ hybridization and compared with in io expression.

为了证明在成形过程中是否也具有相似的分子机制，我们通过原位杂交同体内表达比对的方法来检查小鼠胚胎中调节内胚层和肠道发育的转录因子的表达模式。

METHODS: Tum5 gene was amplified from plasmid pSPORT1Sfi by PCR technique and subcloned into the expression plasmid of lentiviral vector, pGCFU, to generate the lentiviral expression vector, pGCFUTum5. The correct Tum5 gene was confirmed by endoenzyme digestion and sequencing. Recombinant lentiviruses were produced by 293T cells following the cotransfection of pGCFU Tum5 and packaging plasmids-pHelper1.0and pHelper2.0. The resulting recombinant lentiviruses (GCFUTum5) which carried Tum5 and EGFPgene were then used to infect human umbilical vein endothelial cells.

采用PCR技术从含有tumstatin基因的质粒克隆模板 pSPORT1Sfi钓取Tum5基因，并将基因克隆到慢病毒载体表达质粒pGCFU中，构建慢病毒载体表达质粒pGCFUTum5，通过酶切、测序验证Tum5基因后，将pGCFUTum5质粒和包装质粒pHelper1.0，pHelper2.0共同转染人胚胎肾上皮细胞系293T细胞，获得携带Tum5基因和EGFP基因的重组慢病毒GCFUTum5，并转染靶细胞人脐静脉血管内皮细胞。

Results Observing OVC's morphology under transmission electromicroscrope showed that OVC was infantile and undifferentiated with big nucleus, clear nucleolus, large nucleoplasm-ratio, small mitochondria, and little endoplast. In initial stage of damaged liver, OVCs and the expression of ICAM-1 mostly distributed around Hering duct, and then gradually increased and expanded toward hepatic lobule, shown by staining paraffin sections with HE, immunochemistry and transmission electromicroscrope. Immunocytochemistry indicated that ICAM-1 expression on OVCs was positive.

结果 透射电镜下观察到OVCs超微结构的改变为核大，核/浆比大，核仁小，胞浆内细胞器少，可见少量内质网和小线粒体，整个细胞呈幼稚、未分化状态；ICAM-1免疫细胞化学检测阳性；损伤肝组织HE染色和ICAM-1免疫组化检测显示，肝损伤初期，Hering管周围OVCs增生并且ICAM-1阳性表达，随着肝损伤的加重，OVCs继续增生，并且，OVCs沿增生的肝纤维向肝小叶迁移，同时，ICAM-1阳性表达也继续增多，并逐渐向肝小叶弥散分布；透射电镜下观察到，肝损伤初期，OVCs在Hering管周围增生，肝纤维随之增生，增生的OVCs与肝纤维黏附生长。

Objective To investigate the expression of survivin in thyroid carcinoma and its relationship with vascular endothelial growth factor expression.

目的探讨细胞凋亡抑制因子存活素在甲状腺癌中的表达效应及其与血管内皮生长因子表达的关系。

Result The expression of eNOS gene promoted liver regeneration while the expression of IL-10 gene inhibited it.

结果 eNOS的表达同肝细胞的再生呈正相关，而IL-10的表达与其呈负相关。

"The operators will suffer a temporary decrease in the number of consumers and short message services as people may not like having to provide their ID cards for a phone number," Xu Junqi, vice-dean with the Policy-Making Institute of the Telecommunications Research Centre under MII, said yesterday.

信息产业部下属的通信决策研究院副主任徐俊其昨天说：&实行手机实名制后，人们可能不太情愿用身份证注册手机号，所以通信运营商会暂时面临用户减少和短信用户减少的问题。&

I don't believe in make-believe!

我不相信这些虚构的故事。