查询词典 disulfiram

"The cocaine vaccine and disulfiram are probably useful as a combination to first help cocaine patients get abstinent with disulfiram and then prevent relapse with the cocaine vaccine," he commented to Medscape Psychiatry . Disulfiram is available and inexpensive and can be used at 250 mg daily for cocaine dependence.

他向Medscape精神学评论表示，古柯碱疫苗与disulfiram合并疗法对古柯碱滥用病患来说可能是有用的，先以disulfiram戒除再以古柯碱疫苗预防再发；Disulfiram是可取得的且价格低廉，每天服用250 mg用於古柯碱依赖性。

Other research is looking at how disulfiram, an indirect dopamine agonist, might be useful to treat cocaine addiction. By inhibiting the enzyme dopamine beta-hydroxylase, which converts dopamine to norepinephrine, disulfiram reverses stimulant-induced dopamine deficiency, Dr. Kosten explained.

Kosten医师解释，其他研究针对disulfiram是如何作用的，这是一个间接多巴胺致效剂，可能可以有效地治疗成瘾；透过抑制多巴胺贝他水解酵素，这个酵素将多巴胺转换成正肾上腺素，disulfiram逆转刺激剂诱发的多巴胺缺乏。

A nurse is teaching disulfiram to a patient who is addicted to alcohol.

护士在对一名酒精成瘾患者指导戒酒硫的相关知识。

Which of the following statements, if made by the patient, would indicate an adequate understanding if disulfiram?

下列哪种描述，表明此病人正确理解了戒酒硫的用法？

Disulfiram has a dual effect, he noted. It reduces the craving for cocaine that usually occurs 15 minutes or so after the "high" is over. It also enhances the unpleasant nervous paranoia that is seen in about half of cocaine users.

他表示，disulfiram具有双重作用，这个药物降低对古柯碱的渴望，这通常发生在用药的15分钟之内或是因此造成兴奋的感觉过去；有半数使用古柯碱的病患会产生不愉快且紧张的感觉。

Second, the drug disulfiram, which causes acetaldehyde to accumulate in the body, discourages alcoholics from drinking by causing nausea, vomiting, and other severe alcohol flush reaction symptoms.

第二个是，二硫龙作用可以导致乙醛在人体内的积存，乙醛可以减轻人在饮酒后发生的恶心、呕吐和其他由酒精引起的症状反应。

The vaccine study and 3 of the disulfiram studies were done by Dr. Kosten's research group at Yale University, in New Haven, Connecticut, which he left last year, and he is now replicating these studies at Baylor College of Medicine.

疫苗与3个disulfiram的研究是由康涅狄格纽黑文耶鲁大学的Kosten 博士与研究团队完成，他去年已离开，目前在Baylor医学院重复这些研究。

"It looks like in 2 or 3 years we will have a cocaine vaccine on the market," he told the audience. Disulfiram, a generic drug that was approved over 50 years ago by the US Food and Drug Administration for alcohol abuse, is not currently being developed for cocaine abuse, despite fairly robust research findings for this application, he added.

他向听众表示，看起来两、三年内就会有古柯碱疫苗上市；他附带表示，disulfiram，一种在50年前由美国食品药物管理局核准使用於治疗酒精滥用的学名药，目前并未被研发作为古柯碱滥用治疗，尽管相当多严谨的研究结果显示这是可行的。

Ongoing studies have shown that disulfiram also appears useful for methamphetamine abuse, he added. His current research team is developing a methamphetamine vaccine and performing animal studies in partnership with Merck.

Kosten博士补充表示，目前的研究显示disulfiram也对甲基安非他命滥用的治疗是有效的，他的研究小组目前正与默克公司合作研发甲基安非他命疫苗的动物试验。

Individuals with gene variants or haplotypes associated with low levels of dopamine beta-hydroxylase were more likely to attain cocaine-free urine with disulfiram in a study of heavy users of cocaine.

试验中投予disulfiram的严重古柯碱成瘾患者，如因个体基因变异或基因序列单体变异使体内产生较低的多巴胺贝他水解酵素，较容易得到没有古柯碱的尿液。

Therefore, it is imperative that you need to be prepared for the great change that is about to occur.

所以，你需要为快要出现的伟大改变准备好，这是必要的。

If u agree with our suggestion of dicker trade,we will exchange paper with u wood.

如果你方同意我们进行易货贸易的建议，我们将用纸与你们交换木材。