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The effects and mechanism of GABAergic neurons, NOergic neurons, opioid peptide and cyclic adenosine monophosphate in the nucleus reticularis thalami on sleep-wakefulness cycle of rats and the effects and mechanism of the 5-HTergic nerve fibers project from the nucleus raphes dorsalis to RT on sleep-wakefulness cycle of rats were investigated with the methods of brain stereotaxic, nucleus spile, microinjection and polysomngraphy.1. The effects of GABAergic neurons in RT on sleep-wakefulness cycle of rats1.1 Microinjection of 3-mercaptopropionic acid (3-MP, a kind of glutamate decarboxylase inhibitor) into RT. On the day of microinjection, sleep only decreased a litter. On the second day, sleep marked decreased and wakefulness marked increased. On the third and fourth day, sleep and wakefulness stages resumed to normal.1.2 Microinjection of gamma-amino butyric acid (GABA 1.0μg) into RT enhanced sleep and reduced wakefulness compared with control; while microinjection of L-glutamate (L-Glu, 0.2μg) decreased sleep and increased wakefulness; microinjection of bicuculline (BIC, 1.0μg), a GABAA receptor antagonist, enhanced wakefulness and reduced sleep; microinjection of baclofen (BAC, 1.0μg), GABAB receptor agonist, had the same effects as GABA.2. The effects of NOergic neurons in RT on sleep-wakefulness cycle of rats2.1 Microinjection of L-arginine (L-Arg, 0.5μg) into RT decreased sleep compared with control, but there were on statistaical difference between L-Arg group and control; while microinjection of sodium nitroprusside (SNP, 0.2μg), a NO donor into RT, sleep marked decreased and wakefulness marked increased. Microinjection of nitric oxide synthase inhibitor, N-nitro-L-arginine (L-NNA, 2.0μg) into RT enhanced sleep and reduced wakefulness.2.2 After simultaneous microinjection of L-NNA (2.0μg) and SNP (0.2μg) into RT, SNP abolished the sleep-promoting effect of L-NNA compared with L-NNA group; after simultaneous microinjection of L-NNA (2.0μg) and L-Arg(0.5μg) into RT, we found that L-NNA could not blocked the wakefulness-promoting effect of L-Arg.3. The effects of opioid peptide in RT on sleep-wakefulness cycle of rats3.1 Microinjection of morphine sulfate (MOR, 1.0μg) into RT increased wakefulness and decreased sleep compared with control; while microinjection of naloxone hydrochloride (NAL, 1.0μg), the antagonist of opiate receptors, into RT, enhanced sleep and reduced wakefulness.3.2 After simultaneous microinjection of MOR (1.0μg) and NAL (1.0μg) into RT, the wakefulness-promoting effect of MOR and the sleep-promoting effect of NAL were not observed compared with control.4. The effects of cAMP in RT on sleep-wakefulness cycle of rats Microinjection of cAMP (1.0μg) into RT increased sleep and decreased wakefulness compared with control; microinjection of methylene blue (MB,1.0μg) into RT enhanced sleep and reduced wakefulness compared with control.5. The effects of the 5-HTergic nerve fibers project from DRN to RT on sleep-wakefulness cycle of rats5.1 When L-Glu (0.2μg) was microinjected into DRN and normal sodium (NS,1.0μg) was microinjected into bilateral RT. We found that sleep was decreased and wakefulness was increased compared with control; when L-Glu (0.2μg) was microinjected into DRN and methysergide (MS,1.0μg), a non-selective 5-HT antagonist, was microinjected into bilateral RT, We found that sleep was enhanced and wakefulness was reduced compared with L-Glu group.5.2 When p-chlorophenylalanine (PCPA, 10μg) was microinjected into DRN and NS (1.0μg) was microinjected into bilateral RT, We found that sleep was increased and wakefulness was decreased compared with control; microinjection of 5-hydroxytryptaphan (5-HTP, 1.0μg), which can convert to 5-HT by the enzyme tryptophane hydroxylase and enhance 5-HT into bilateral RT, could block the effect of microinjection of PCPA into DRN on sleep-wakefulness cycle.
本研究采用脑立体定位、核团插管、微量注射、多导睡眠描记等方法,研究丘脑网状核(nucleus reticularis thalami,RT)中γ-氨基丁酸(gamma-amino butyric acid ,GABA)能神经元、一氧化氮(nitrogen monoxidum,NO)能神经元、阿片肽类神经递质、环一磷酸腺苷(cyclic adenosine monophosphate,cAMP)及中缝背核(nucleus raphes dorsalis,DRN)至RT的5-羟色胺(5-hydroxytryptamine,5-HT)能神经纤维投射对大鼠睡眠-觉醒周期的影响及其作用机制。1 RT内GABA能神经元对大鼠睡眠-觉醒周期的影响1.1大鼠RT内微量注射GABA合成关键酶抑制剂3-巯基丙酸(3-MP,5μg),注射当天睡眠时间略有减少,第二日睡眠时间显著减少,觉醒时间明显增多,第三、四日睡眠和觉醒时间逐渐恢复至正常。1.2大鼠RT内微量注射GABA受体激动剂GABA( 1.0μg)后,与生理盐水组比较,睡眠时间增加,觉醒时间减少;而RT内微量注射L-谷氨酸(glutamic acid, L-Glu, 0.2μg)后,睡眠时间减少,觉醒时间增加;RT内微量注射GABAA受体阻断剂荷包牡丹碱(bicuculline,BIC,1.0μg)后,睡眠时间减少,觉醒时间增加;RT内微量注射GABAB受体激动剂氯苯氨丁酸(baclofen,BAC,1.0μg)后,产生了与GABA相似的促睡眠效果。2 RT内NO能神经元对大鼠睡眠-觉醒周期的影响2.1大鼠RT内微量注射NO的前体L-精氨酸(L-Arg,0.5μg)后,与生理盐水组对比,睡眠时间略有减少,但无显著性意义;而RT内微量注射NO的供体硝普钠(Sodium Nitroprusside,SNP,0.2μg)后可明显增加觉醒时间,缩短睡眠时间;微量注射一氧化氮合酶抑制剂L-硝基精氨酸(L-arginine,L-NNA,2.0μg)后,引起睡眠时间增多,觉醒时间减少。2.2大鼠RT内同时微量注射L-NNA(2.0μg)和SNP(0.2μg)后与L-NNA组比较发现SNP逆转了L-NNA的促睡眠作用;RT内同时微量注射L-NNA(2.0μg)和L-Arg(0.5μg)后,与L-NNA(2.0μg)组比较发现L-Arg可以增加觉醒而缩短睡眠,其促觉醒作用未能被NOS的抑制剂L-NNA所逆转。3 RT内阿片肽对大鼠睡眠-觉醒周期的影响3.1大鼠RT内微量注射硫酸吗啡(morphine sulfate,MOR,1.0μg)后与生理盐水组对比,睡眠时间减少而觉醒时间增加; RT内微量注射阿片肽受体拮抗剂盐酸纳洛酮(naloxone hydrochloride,NAL,1.0μg)后与生理盐水组比较,睡眠时间增加而觉醒时间减少。3.2大鼠RT内同时微量注射MOR(1.0μg)和NAL(1.0μg)后,与生理盐水组对比,原有的MOR促觉醒效果和NAL的促睡眠效果都没有表现。4 RT内环一磷酸腺苷信使对大鼠睡眠-觉醒周期的影响大鼠RT内微量注射cAMP(1.0μg)后与NS(1.0μg)组比较,睡眠时间增多而觉醒时间减少;RT内微量注射亚甲蓝(methylene blue,MB,1.0μg)后,与NS组比较,睡眠时间增多而觉醒时间减少。5中缝背核投射到丘脑网状核的5-羟色胺能神经纤维对大鼠睡眠-觉醒周期的影响5.1大鼠DRN内微量注射L-Glu(0.2μg),同时在双侧RT内微量注射NS (1.0μg)后,与对照组(DRN和双侧RT注射NS, 0.2μg)比较,睡眠时间减少,觉醒时间增多;大鼠DRN内微量注射L-Glu(0.2μg),同时在双侧RT内微量注射二甲基麦角新碱(methysergide, MS, 1.0μg )后,与对照组(DRN注射L-Glu 0.2μg,双侧RT注射NS 1.0μg)比较,睡眠时间增多,觉醒时间减少。5.2大鼠DRN内微量注射对氯苯丙氨酸(p-chlorophenylalanine,PCPA,10μg),同时在双侧RT内微量注射NS (1.0μg)后,与对照组(DRN和双侧RT注射NS, 1.0μg)比较,睡眠时间增多,觉醒时间减少;大鼠DRN内微量注射PCPA(10μg),产生睡眠增多效应后,在双侧RT内微量注射5-羟色胺酸(5-hydroxytryptaphan , 5-HTP, 1.0μg )后,与对照组(DRN注射PCPA 10μg,双侧RT注射NS 1.0μg)比较,睡眠时间减少,觉醒时间增多。
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"May I bring, may I bring,may I bring you a salad?May I bring,may I bring you a salad?Would you like a cup of coffee?How about some herbal tea?May I bring you some dessert?"
贸易梯梯TT外贸学院,有权但无此义务,改善或更正所刊登信息任何部分之错误或疏失。
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To sb's notice bring/call to mind bring to a halt bring into action catch one's breath call down / lay a curse upon sb. cast a shadow over catch at shadows catch sb's eye catch fire catch / get a glimpse of catch sight of come to sb's knowledge come to sb's notice come to a point come /go into effect come into a fortune come into fashion come to a halt combination with commander in chief communication with commit a crime commit / make an error come into possession of sth. come / go into operation come to one's senses come to / arrive at a decision come to / arrive at an agreement with reach / make an agreement with come to sb.'s assistance complaint about/of competition with / against sb.
do a threat to do damage to do/try one's best 与----接触不平衡与-----保持友好与----一致对----负责违背诺言实施,使生效给某人带来羞辱使某人注意----想起使停止采取行动喘息诅咒某人蒙上阴影捕风捉影引人注目着火,烧着对----瞥一眼看见被某人知道引起某人的注意到紧要关头实施,生效继承一笔财产开始流行停止与------结合总司令与-----交流,与----通信犯罪犯错误占有某物实行,生效恢复理性,苏醒过来做出决定与-------达成一致与-------达成一致帮助某人对------抱怨与某人竞争对----有威胁损害-----尽力,努力
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In autumn, always bring people pleased celebrate, bring poetry, bring fancy, bring to imagine, bring a hope more, but this year's autumn, not- same sort, more and not and usually.in this fine season, arrive to°from chiang-nan water country a northland backland, from the gan river strand to pull sa lin ka, hot soils of republic each square kilometer soak through exultant and happiness, flow to drip sweet with sing.1,300,000,000 china childrens with heroic the singing arousing more put to fly aureate ideal and imagining of rose and put to fly hard go such as the conviction of huge rock and the poem lauding to the great motherland.
秋天,总给人们带来喜庆,带来诗意,带来遐想,带来憧憬,更带来希望,而今年的秋天,非同一般,更不寻常。在这美好的季节,从江南水乡到北国边陲,从赣江只滨到拉萨林卡,共和国每一平方公里的热土都浸透着欢欣与幸福,流淌着甜蜜与歌唱。十三亿华夏儿女以豪迈激越的歌声放飞金色的理想与玫瑰色的憧憬,放飞坚如磐石的信念与对伟大祖国赞美的诗行。
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In autumn, always bring people pleased celebrate, bring poetry, bring fancy, bring to imagine, bring a hope more, but this year's autumn, not- same sort, more and not and usually.in this fine season, arrive to°from chiang-nan water country a northland backland, from the gan river strand to pull sa lin
秋天,总给人们带来喜庆,带来诗意,带来遐想,带来憧憬,更带来希望,而今年的秋天,非同一般,更不寻常。
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When left when the test-drive after repair in shop main engine is adding this ship to 540r/min, supercharger occurrence asthma brace up phenomenon, rotate speed lifts slightly again, noise shakes very big, smoke evacuation temperature is normal, hair of on the high side of temperature of air inlet duct is very hot, as good as of smoke evacuation smoke constant, supercharger rotor rotate speed and the rotate speed of right leader supercharger that work normally comparative. 2 breakdown analyse this model diesel engine supercharger breathes heavily brace up the reason has the following sides. Bearing of 1 supercharger rotor damages, bring about on the low side of supercharger rotor rotate speed or wave motion, make inadequacy of compressor part air feed and diesel engine and its demand do not match, bring about air current not to stabilize generation to breathe heavily brace up. 2 diesel engine offers oil, match gas to time forbid, match gas, draw well time and disorder, bring about supercharger to breathe heavily brace up. 3 supercharger nozzle jams, cause smoke evacuation not free, circumfluence of exhaust stroke waste gas, enter jackknife of new energy of life with the below one stroke that take energy of life, produce air current to hit generation to breathe heavily brace up. Canal of 4 smoke evacuation jams, smoke evacuation not free, bring about waste gas circumfluence, hit generation of new energy of life to breathe heavily brace up. 5 jams into gas mouth, enter gas inadequacy, generation breathes heavily brace up. 3 trouble removal are based on above analysis, adopt the following measure to remove trouble.
该舰在厂修后试车时左主机在加至540r/min时,增压器出现喘振现象,转速再略升高,声响震动很大,排烟温度正常,进气管温度偏高发烫,排烟烟色无异常,增压器转子转速和正常工作的右主机增压器转速相当。2故障分析该型柴油机增压器喘振的原因有以下几个方面。1增压器转子轴承损坏,导致增压器转子转速偏低或波动,使得压气机部分供气不足和柴油机及其需求不匹配,导致气流不稳定产生喘振。2柴油机供油、配气定时不准,配气、发火定时紊乱,导致增压器喘振。3增压器喷嘴堵塞,导致排烟不畅,排气冲程废气回流,和下一进气冲程进新气重叠,发生气流冲撞产生喘振。4排烟管堵塞,排烟不畅,导致废气回流,冲撞新气产生喘振。5进气口堵塞,进气不足,产生喘振。3故障排除基于以上分析,采取以下办法排除故障。
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I think that for every movie I make, I always try to duplicate that feeling of purity and innocence that I got when I saw this movie,'' he said.''I bring in Western drama. I bring in metaphor. I bring in Jean-Luc Godard. Whatever I bring in to my own films, I am forever trying to update and recapture that feeling.
我每拍一部电影都试图复制我看这部电影时得到的纯净天真的感受,我将它们带入西方戏剧,带入每个隐喻,带入戈达尔,带入我自己的电影,我永远都试图更新和找回那种感受。
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A call decider analyzes bring-up call information associated with a phone number mapped to a predetermined character among the collected bring-up call information, numerically quantizes the analyzed bring-up call information, and determines the growth stage of the character according to the numerical bring-up call information.
呼叫判定器分析所收集的养育呼叫信息之中的与映射到预定角色的电话号码相关联的养育呼叫信息,对所分析的养育呼叫信息进行数字量化,并根据数字养育呼叫信息来确定角色的成长阶段。
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Anaesthetise , anaesthetize , anesthetise , anesthetize , put out , put to sleep , put under bring around , bring back , bring round , bring to
页面简介:沪江小D免费英语在线翻译网站提供put under是什么意思,put under的翻译、音标与发音、含义及用法、参考例句等信息。
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Hey yo jim man why don't ya, you don't you kick some of that you know you know how you do it man it's a trip people don't even believe were together right now but tell your story you know the one i like say it for me riders on the storm riders on the storm into this house we're born (into this house we're born) into this world we're thrown (into this world we're thrown) like a dog without a bone an actor out on loan riders on the storm there's a killer on the road his brain is squirmin' like a toad take a long holiday let your children play if ya give this man a ride sweet family will die killer on the road, yeah goin' off of this off of that with the lizard king bumpin' in the back how bout that driftin', liftin', swiftin', coastin', testaroastin' but the wheels won't stop 200 on the highway fresh up off the block he's a rider, na he's a killer dresses in all black but his hat says stealla pedal to the metal i gotta go hard drive by and say hello hey fredwreck you my mello now let me here what i sound like acapella wow ride dip swish now bring it back just like this like a dog with out his bone unlike a g with out his chrome it's hard to imagine the homey dog in a jag and he's checkin' for the checkered flag comin' in first never in last cause my car to fast i neva eva run out of gas cause i just to clean i do it upper class so fasten your seat belts its so hot it will even make heat melt so get a bowl and roll and ride slip through the slip and slide like a dog without a bone an actor out on loan riders on the storm there's a killer on the road his brain is squirmin' like a toad take a long holiday let your children play if ya give this man a ride sweet family will die killer on the road, yeah need for speed i'm trying to take the lead hold on little homey before you run into the trees i've seen thinks that i would have never saw before hey yo jim let'em in, let'em in open up my back tire smokin' the whole street and now the police wanna flash there lights and chase the dogg all night but i won't pull over nor give up cause i just don't give a fuck yeah from the side boy where we was born and raised straight up to ride boy continuously, we get to an expeditiously keep the light on east side on snoop dogg and the doors and yeah we bout to ride on riders on the storm riders on the storm into this house we're born into this world we're thrown were thrown
嘿摇摇弯轨机人为什么不唉,你不你踢一些那你知道你知道如何你这样做人这是一次旅行人们甚至不相信是在一起此时但告诉你的故事你知道那个我像为我说它骑士在暴风雨上骑士在暴风雨上入这房子我们是出生入这世界我们是扔像个狗没有一根骨头一个演员那儿有一个杀手在路上他的大脑是squirmin'像个癞蛤蟆采取一个长的假期让你的孩子们玩如果唉给这人一个乘甜家将死凶手在路上,是呀去'离开对于这离开关于那和蜥蜴国王 bumpin'在后面如何拳击比赛那 driftin',liftin',swiftin',coastin',testaroastin'但是这个车轮不会停止两百在公路上新鲜向上远离块他的一个骑士,娜他的一个杀手衣服在纯黑但他的帽子说stealla 踩踏板金属我有去难驶过和问好嘿fredwreck 你我的梅洛现在让我这里什么我听起来像acapella 哇骑现在倾斜豪华带来它回来只是这样像个狗与出来像个狗没有一根骨头一演员借出的骑士在暴风雨上那儿有一个杀手在路上他的大脑是squirmin'像个癞蛤蟆采取一个长的假期让你的孩子们玩如果唉给这人一个乘甜家将死凶手在路上,是呀需要速度我是试图着先鞭继续小像家一样在你未碰撞树木我已经看到想那我从来不锯在以前嘿摇摇弯轨机让'em 在,让'em 在开发我的后面疲劳smokin'一街一巷那么警察要闪光那儿灯光和追逐道格整夜但我不会拦截也不放弃造成我只是不给一个性交是呀自边男孩我们在那里出生和提升直直至骑男孩骑士在暴风雨上骑士在暴风雨上入这房子我们是出生入这世界我们是扔我的翻译不太标准别见怪
- 相关中文对照歌词
- Bojangles
- Bring It Back
- You Can't Bring Me Down
- Bootie Call
- Funkadelic Relic
- Bring Your Smile
- Bring 'Em All In
- Bring It Back (Remix)
- Bring It Back DJ
- So Bring It On (Remix)
- 推荐网络例句
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Panorama Many people are dancing in a large sitting room.
在一个大客厅里,许多人在跳舞。
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We fully understand how a microwave oven cooks food, it is first necessary to talk ...
我们充分理解一个微波炉煮的食物,这是首先要谈。。。
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The age of the patient is, therefore, almost equivalent to the duration of HBV infection.
因此患者的年龄几乎与乙肝病毒感染的病程相似。