查询词典 Cervical

The cutoff value of E2/E6, used to distinguish the pure episomal form from a mixed form of episomal and integrated HPV16 DNA, was 0.81 in the multiplex real-time PCR test. c） HPV16 existed as episomes in most of the CIN Ⅰ lesions, and 42.9% of them had mixed episomal/integrated HPV16. The integrated form of HPV16 constituted the majority in most of the CIN Ⅱand CIN Ⅲ cases. In squamous cervical carcinomas, the HPV16 was mostly integrated into the host chromosome. d） The rate of HPV16 integration was associated with the degree of cervical lesions and the rate increased with the progression of cervical disease, e） The rate of pure integrated HPV16 in stage Ⅱ and Ⅲ（88%） was higher than that in stage Ⅰ（33.3%）. Conclusions: a） Multiplex real-time PCR is a rapid and sensitive method for detection of the integration state of HPV16 DNA. b） The integration of HPV16 DNA is a very early event in the development of cervical cancer and may act as an activation mechanism for progression from preinvasive to invasive cervical cancer, c） The pure integrated HPV16 in cervical cancer may be a useful prognostic indicator.

HPV—16E2、E6标准曲线相关系数均为1.00，扩增效率均在95％以上：2）确定0，81作为多重实时PCR区分游离型和混合型HPV-16的界值、3）CINⅠ中HPV—16大多以游离方式存在，但仍有整合的发生（42，9％）；CINⅡ和CINⅢ中HPV—16以混合型为主：浸润癌中以整合型HPV—16为主。4）HPV-16整合发生率与不同程度的宫颈病变有关，并且随着宫颈病变级别的升高HPV-16整合发生率呈上升趋势-5）Ⅱ＋Ⅲ期宫颈癌中整合型HPV—16所占比例显著高于Ⅰ期宫颈癌结论：1）多重实时定量PCR是一种敏感性高、简便快速的HPV—16病毒存在状态的检测方法2）HPV-16整合是宫颈癌变的早期事件，与宫颈癌前病变的进展有关。3）宫颈癌中整合型HPV—16的发生可能具有预后价值

Results ①p53 positive expression rate in cervical carcinomas 85.71%( 30 /35) was significantly higher than that in normal cervixes 6.67%( 2 /30),P= 0.001.②p53 expression is correlated with the differentiation state and pathologic grades.The positive expression rate of p53 in the cervical carcinomas of grades Ⅰ 57.14%(8 /14) was significantly lower than that in the cervical carcinomas of grades Ⅱ 86.67%(13 /15) and grades Ⅲ 100.0%(6 /6),P＜0.05.③The positive rate of PCNA in the cervical carcinoma of grade Ⅰ 64.29% was signifi cantly lower than that in the grade Ⅱ 93.33% and grade Ⅲ 100.0%,P＜0.05.Conclusion Our data indicate that the alteration of p53 is involved in cervical carcinoma.

结果 ①P53蛋白在宫颈癌组织中的表达率为85.71%(30 /35)，明显高于在正常宫颈组织中的表达率6.67%( 2 /30)，P = 0.001；②P53蛋白阳性表达率与宫颈癌组织的病理学分级有关，P53在宫颈癌Ⅰ级中的阳性表达率57.14%（8 /14）明显低于Ⅱ级86.67%（13/15 和Ⅲ级100.0%(6/6)，P＜0.05；③宫颈癌组织PCNA阳性表达率Ⅰ级64.29％明显低于Ⅱ级93.33％和Ⅲ级100.0%，P＜0.05。

Abstract］ objective to explore the accuracy and safety of safety drillprepared for cervical pedicle screw trajectory.methods fourteen adult cadaver specimens of cervical spine（c3～c7）with intact structures including ligaments and perivertebral muscles were reserved and used.according to the radiographic measurements,safety drill was inserted into cervical pedicle individually.the evaluation of the drill's trajectory was carried out by ct scan and three-dimension reconstruction and autopsy.results one hundred and forty drill's trajectories were made.9 holes failed with a perforation rate of 6.4%.conclusion the safety drill prepared for cervical pedicle screw hole is safe and effective and can be applied and popularized clinically.

目的 探索安全钻头应用于颈椎弓根螺钉孔道钻探的安全性与准确性。方法随机取14具福尔马林浸泡的成人颈椎标本（c3～c7），保留完整的脊柱三柱结构及相关的韧带和椎旁肌，根据影像学测量的进钉点和进钉方向，模拟颈椎后路手术过程。选用安全钻头，进行实际的颈椎弓根螺钉孔道的钻探，将孔道行ct扫描，并斜位三维重建孔道形态，并以肉眼直视观察结果为金标准，评价孔道钻探的成败。结果钻探孔道准确率89.3%（125/140），穿孔率6.4%（9/140）。结论安全钻头应用于颈椎弓根螺钉孔道钻探的安全性与准确性均较高，可以在临床上推广使用。

At present, there are no cervical spine models suited to the character of the Chinese on the injury mechanism of the cervical spine. CT technology was used to get the data of the vertebras, which were obtained from Chinese 50th percentile volunteer's cervical spine, and a finite element model of the cervical spine was established.

针对目前在颈部损伤机理的研究中尚未有适合中国人体型特点的全颈椎有限元模型的情况，采用CT技术获取中国50百分位人体颈椎数据，并以此建立了全颈椎有限元模型。

Objective To investigate the cervical cold knife conization of care to prevent cervical cold knife conization after cervical bleeding, postoperative com plications, such as cervical stenosis.

目的 探讨宫颈冷刀锥切术的护理方法，防止宫颈冷刀锥切术后宫颈出血、宫颈狭窄等术后并发症。

According to the characteristics of cervical disease and cervical human natural physiological curvature, Head back to use the self continue to play a small role in the weight of traction, the 26 Pillow taste of Chinese herbal medicine, directly on the neck and improve local blood circulation, ease muscle cramps, relieve the sense of Feel oppressed nerve endings to reduce the local tissue tension, anti-inflammatory, analgesic, sedative, to ease rapidly brought about by a variety of cervical spondylosis discomfort, treatment and prevention is ideal for cervical spondylosis.

根据颈椎病的发病特点及人体颈椎自然生理曲度，利用头部后仰的自重起到持续小重量的牵引作用，枕芯的26味中草药，直接作用于颈部，改善局部血液循环，缓解肌肉痉挛，减轻感觉神经末梢压迫，减少局部组织张力，消炎、镇痛、安神，迅速缓解颈椎病带来的各种不适，是治疗和预防颈椎病的理想产品。

Our results suggests that the gene aberrant of PIK3CA and PTEN werecorrelated with the cervical cancer. Tumor progression in the cervical epithelium isaccompanied by increase of PIK3CA or loss of PTEN protein expression, which ismutually exclusive events in cervical tumorgenesis.

结论PIK3CA和PTEN基因改变与宫颈癌的发生有关，宫颈癌的发展过程伴随着PI3K p110a蛋白或PTEN蛋白的表达异常，然而在宫颈癌发生过程中PIK3CA高表达或PTEN缺失是单独存在的。

The relative factors include the degree of cervical erosion,character of cervical grume,degree of vaginal cleanness;puriform cervical grume,poor vaginal cleanness have higher positive rate of all kinds of pathogens.

为了提高慢性宫颈炎电灼后的治愈率，必须对患者进行病原体的检测；临床宫颈糜烂程度深、宫颈粘液性状脓性、阴道清洁度差者应先给予药物治疗。

The unnatural expression KAIl and P53 were early event in indevelopment of cervical cancer,their may be two good factorys in early diagnosis in cervical cancer,the overexpression of P53 is associated with the pathological grade and evaluating prognosis of cervical carcinoma.

自CIN ⅡP53的表达率明显增高，与正常宫颈组织的阳性表达率差异有显著性(P〈0.005)，与SCC的阳性表达率差异无显著性(P〉0.01)，CINI1与CIN ⅢP53的阳性表达率差异无显著性(P〉0.05)。P53的表达与SCC的临床分期(P〉0.01)、淋巴结转移(P〉0.01)、发病年龄均无关P〉0.01

Objective: To investigate the expression of Survivin and Bcl-2 in cervical intraepithelial neoplasia and cervical carcinoma, and to explore the role of them in cervical carcinoma pathogenesis.

目的：研究Survivin、Bcl-2在宫颈上皮内瘤变及宫颈癌中的表达，探讨两者在宫颈癌发病机制中的作用。

Foods high in this vitamin include oily fish such as salmon, tuna and, and fish liver oils.

维生素D含量高的食物包括诸如大麻哈鱼、金枪鱼和鲭鱼之类的油鱼以及鱼肝油。

We need you to cosign our public letter demanding that press intimidation cease immediately, and that all charges be dropped.

我们需要您cosign我们的公共信，要求记者立即停止恐吓，并要求所有收费下降。