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Methods The experimental model of mice with PDS was induced by rhubarb decoction. Then the mice were treated with three dosages of SJZD (12.5, 25, and 37.5 g/kg), respectively. The body weight, body temperature, mean retention time of chyme in digestive tract, gastric emptying velocity, gastrin and motilin levels, and visceral index of mice were measured.
方法大黄煎液制备小鼠脾虚证模型后，以3种剂量(12.5、25、37.5g/kg)的四君子汤进行治疗，测定小鼠体重、体温、消化道内食糜平均滞留时间、胃排空速率、胃泌素与胃动素水平、脾脏和胸腺脂数。
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Immunohistochemical method was used to detect avian leukosis virus subgroup J from egg-type chicken, which was preliminarily diagnosed to appear subgroup J avian leukosis. The organs from these chickens were examined by ALV-J gp85 monoclonal antibody, these organs included marrow, liver, spleen, kidney, lung, heart, pancreas, oviduct, ovary, ventriculus glanduaris, skeletal muscle, cerebrum, ischiacticus nerve.
采用免疫组化法，对病理学初步诊断为蛋用型鸡 J亚群白血病的自然发病鸡的肿瘤、骨髓、肝脏、脾脏、肾脏、肺脏、心脏、胰脏、输卵管、卵巢、腺胃、骨骼肌、大脑、坐骨神经，用特异性抗 J亚群禽白血病病毒囊膜糖蛋白gp85的单克隆抗体进行检测，待检的组织切片中均检出阳性抗原，免疫组化的研究结果与病理学诊断结果相一致。
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The results of study show:1. White pulp and red pulp in parenchyma of spleen of embryo can be obviously discerned after 18 days. Periarterial lymphoid sheath and ellipsoid periarterial lymphoid sheath also can be obviously discerned in spleen of 4 days chicken. T, B lymphocytes in appendix basement of embryo emerge after 20 days. It is the initial shape of cecal tonsil. Crypt structure of conjunction of esophago and stomachus glandularis form obviously at 4 days. It is the initial shape of esophago tonsil. The germinal center firstly emerges in these three organs at 14 days. With the increase of day age, the characteristic structure peripheral immune organs gradually develop mature. Spleen achieve mature at 21 days and cecal tonsil at 35 days.2. IgM~+ and IgA~+ cells in spleen of embryo emerge at 15 days. IgG~+ cell, CD3~+ and CD8~+T lymphocytes of embryo emerge at 20 days. CD3~+, CD8~+ and IgM~+ cells in cecal tonsil of embryo emerge at 20 days. However CD4~+, IgG~+ and IgA~+ cells all emerge in 1 day age chicken out of crust. CD3~+, CD4~+, CD8~+, IgM~+ and IgG~+ cells in esophago tonsil of embryo all emerge at 20 days. However IgA~+ cells emerge in 1 day age chicken out of crust.3. The amount of T, B lymphocytes in peripheral immune organs increase follow with the increase of day age, and hold an upgrade tendency. The amount of T, B lymphocytes in spleen achieved stabilization at 21 days, and in tonsil of esophago and appendix at 35 days.
研究结果表明：1、在组织结构方面，脾脏实质内的白髓与红髓在胚胎18日龄后明显可辨，4日龄雏鸡脾脏中形成明显可辨的动脉周围淋巴鞘和椭球周围淋巴鞘；盲肠基部T、B淋巴细胞在胚胎20日龄时开始出现，即初步形成盲肠扁桃体；食管与腺胃结合处在4日龄时形成明显的隐窝结构，即食管扁桃体初步形成；14日龄时，三种器官中首次出现生发中心；随着日龄的增长，外周免疫器官特征结构不断发育成熟，脾脏在21日龄时达到成熟水平，盲肠扁桃体和食管扁桃体在35日龄时达到成熟水平。2、在T、B淋巴细胞出现时间方面，脾脏中IgM~+和IgA~+细胞在胚胎15日龄时开始出现，IgG~+细胞、CD3~+和CD8~+T淋巴细胞在胚胎18日龄时出现，CD4~+细胞在胚胎20日龄时出现；盲肠扁桃体中CD3~+、CD8~+和IgM~+细胞在胚胎20日龄时开始出现，而CD4~+、IgG~+和IgA~+细胞均在雏鸡出壳后1日龄时出现；食管扁桃体中CD3~+、CD4~+、CD8~+、IgM~+和IgG~+细胞均在胚胎20日龄时开始出现，而IgA~+细胞则在雏鸡出壳后1日龄时出现。3、在T、B淋巴细胞数量变化方面，外周免疫器官中T、B淋巴细胞的数量随日龄增长，整体均呈上升趋势。
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Results ①The most common lesions were the extragastric compressions caused by spleen, which accounted for 54.74%, followed by the enlarged gallblodder, hepatic cyst and carcinoma in the left lobe, left kidney, pancreatic cystic adenoma and pancreatic cyst.②The diagnostic accurancy of EUS was 100%, which was higher than that of USP.③Most of the lesions, benign or malignant, had normal structure of the gastric wall.④Splenomegaly only accounted for 38.46% in the lesions caused by the compression of spleen, which were slightly to moderately enlarged.⑤The location of the lesion was usually related to the organ which caused the extragastric compression.
结果 ①胃外压性隆起中脾脏压迫最多见，占54.74%，其余为肿大胆囊、肝右叶囊肿、肝左叶癌、左肾、胰腺囊腺瘤和胰腺囊肿；②EUS对胃外压性隆起的诊断正确率达100%，其对外压灶的完全显示率高于微超声探头；③良性胃外压灶及多数恶性肿瘤胃外压灶其所压胃壁结构均正常；④脾脏压胃者中脾肿大仅占38.46%，且均为轻、中度脾肿大；⑤胃隆起部位与外压灶的种类相关联。
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The test groups were drenched orally with different dosages of compound Radix scutellariae granules. After being drenched orally for ten days, their thymus-index and spleen-nidex, immune globulins of IgA, IgG, IgM and alexins of C3, C4 of serum were defermined, and experiments in vivo were done. The mice-spleen's lymphocytes which were cultured in vivo were added with different concentrations of compound Radix scutellariae granules. The lymphocytes translation stimulate indexes were measured. The ability of licking up neutral red of the peritoneal macrophages cultured in vivo was measured in the groups.
应用复方黄芩颗粒给小鼠灌胃10d后，分别测定对照组与实验组胸腺指数、脾脏指数和血清中的免疫球蛋白IgA、IgG、IgM和补体C3、C4；并且进行体外实验，用不同浓度的复方黄芩颗粒剂对小鼠脾脏淋巴细胞进行体外培养，测定淋巴细胞转移刺激指数；在体外培养测定细胞吞噬中性红的能力。
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Diseased cobias were collected from some net-cage farms at Hsiqu Liouchiou Island, next to Dunggang, Taiwan. Some little nodes appeared on surfaces of their fins and skins. When the symptom became serious, they looked like sarcomas. Almost every organ, including liver, spleen, kidney, fin, heart, stomach, intestine of a hard-sick cobia were dealt through the following processes:fixation, section and staining. Only at the connective tissues of fins and epithelium did we find hypertrophy cells which own big nuclei and inclusion bodies around the nuclei.
中文摘要本实验自屏东小琉球采集某家养殖业者箱网网中的罹病海鲡，外观上，鳍与部分体表出现结节状之小颗粒，严重时，呈现瘤状肉柄，取其各部位组织包括：肝脏、脾脏、肾脏、鳍、心脏、胃、肠等进行固定、切片及染色，发现唯有於鳍与皮肤部位之结缔组织细胞，明显可见肥大之现象，肥大之细胞拥有巨大细胞核与围绕著细胞核的包涵体网状结构，由於肥大细胞之堆叠，导致鱼体之鳍与一些表皮部位有颗粒状的「结节」存在。
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gastrosoph：美食专家
gastroscopy 胃镜检查法 | gastrosoph 美食专家 | gastrosplenic 胃与脾脏的
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gastrosplenic：胃与脾脏的
gastrosoph 美食专家 | gastrosplenic 胃与脾脏的 | gastrostege 蛇腹部之鳞
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gastrosplenic：胃与脾脏的 (形)
gastroscopy 胃镜检查 (名) | gastrosplenic 胃与脾脏的 (形) | gastrostomy 胃造口术 (名)
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gastrostege：蛇腹部之鳞
gastrosplenic 胃与脾脏的 | gastrostege 蛇腹部之鳞 | gastrostomy 胃造口术
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hypersplenism：脾机能亢进
临床上所谓的门静脉高压症(Portal Hypertension)实际上是指门静脉压力异常、持续升高并伴有门静脉与体循环之间交通支过度开放、脾脏肿大、甚至腹水形成这样一种临床综合征. 患者可能发生食管、胃底或消化道其它部位粘膜下静脉曲张破裂出血,腹水、脾脏肿大...1.脾肿大(Splenomegaly)、脾机能亢进(Hypersplenism)