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METHODS: We searched for abnormalities of the proapoptotic Bcl-x deamidation pathway in primary cells from patients with chronic myeloid leukemia or polycythemia vera, myeloproliferative disorders associated with the BCR-ABL fusion kinase and the Janus tyrosine kinase 2 (JAK2) V617F mutation, respectively.

我们分别对来自慢性粒细胞白血病或真性红细胞增多症、骨髓增生性疾病相关的BCR-ABL融合蛋白激酶及Janus酪氨酸激酶2 (JAK2) V617F突变体患者原代细胞凋亡前Bcl-x脱酰胺途径的异常情况进行研究。

Take out of the locking intramedullary pin from the patient with femur' s disunion,and debride thoroughly,then transplant the fibula of the patient himself to the femur' s medullary cavity and transplant the ilium to the location of the disunion.

对15例股骨骨折带锁髓内针内固定术后骨不连患者行取出髓内针,彻底清创,自体腓骨髓内移植,骨不连处植髂骨,全身抗感染和局部持续灌注冲洗引流。

We examined the properties of DC associated with immune suppression in NOD mice by insulin injection subcutaneously and ability to suppress diabetes transfer by diabetogenic effect cells in secondary NOD severe combined immunodeficiency recipients.

NOD小鼠皮下注射牛胰岛素诱导免疫抑制,以血糖检测、胰腺组织学分析和胰岛beta细胞凋亡分析观察自身抗原的免疫保护作用,分离骨髓树突状细胞细胞,流式细胞术分析细胞表面抗原,混合淋巴淋巴细胞反应测定细胞功能。

BACKGROUND: Bone marrow mesenchymal stem cells may directionally differentiate into chondrocytes.

背景:骨髓间充质干细胞可定向诱导为软骨细胞。

Objective To study the method of inducing human marrow mesenchymal stem cells into osteoblasts directionally and to identify osteogenesis characteristics.

目的:探讨将成人骨髓间充质干细胞定向诱导分化为成骨细胞的方法,并对所诱导细胞的成骨特性进行鉴定。

Four proteasome genes and 3 ubiquitin genes were distinguishingly expressed in bone marrow CD34〓 cells.

骨髓CD34〓细胞高表达的基因中,有4个蛋白酶体基因和3个泛素基因。

The bone dosimetric values are influenced by the parameters of skeleton mass.

鉴于骨骼组织不同部位的辐射敏感性存在差异[2],特别是已确认骨髓的造血干细胞和衬在骨表面上的成骨细胞是骨骼中致癌危险的靶细胞,因而ICRP30号出版物[3]详细介绍了估算骨骼靶器官的吸收剂量的骨剂量学模型,使骨剂量的计算趋向精确。1995年,ICRP又专门编著了用于辐射防护的骨骼解剖和生理参数的70号出版

From the theoretical angle, to analyze and summarize the morbility reason of Senile Osteoporosis, to approach the effect of the flavone of rhizome drynaria on the lipidision of marrow stroma cell, as well as the senescence and apoptosis of osteoblast through the experimental study; from the clinical angle, to observe the clinical effect of the flavone of rhizome drynania on Senile Osteoporosis, to supply scientific theory basis for clinical application.

从理论角度分析总结老年性骨质疏松症的发病原因,并通过实验研究探讨骨碎补总黄酮对骨髓基质细胞脂质化的影响,以及对成骨细胞衰变和凋亡的影响,从临床角度观察其治疗老年性骨质疏松症的效果,为临床应用提供科学理论依据。

Results We can induce MSCs into osteoblasts which can express gene col Ⅰ and ALP. Through analysis growth curve, we demostrateed the diphosphonate or assemble flavone of drynaria rhizome with 10^(-4)~10^(-6)mmolL^(-1) had the inhibition on the osteomast; it with 10^(-8)mmolL^(-1) had a promotion on the osteoblast; it with 10^(-10)~10^(-12)mmolL^(-1) had a restraint on osteoblast. Conclusion Through gene analysis, we found the diphosphonate or assemble flavone of drynaria rhizome can have the promotion on the osteoblast.

结果 骨髓基质细胞经过4周诱导可转化为表达colⅠ和ALP的成骨细胞,经过生长曲线分析,二磷酸盐和骨碎补总黄酮10^(-4)~10^(-6)mmolL^(-1)时,对诱导后的成骨细胞有抑制作用;10^(-8)molL^(-1)有促进作用;10^(-10)~10^(-12)mmolL^(-1)不明显,其中10^(-8)mmolL^(-1)作用最强;基因分析后,发现二磷酸盐和骨碎补总黄酮促进成骨细胞表达colⅠ和ALP,且两者合用效果大于单独用药。

Dult precursor B2ALL with BCR/ ABL gene rearrangements displays a unique immunophenotype based on the pattern of CD10 , CD34 , CD13 and

ML1/ ETO 融合转录因子在白血病患者化疗及骨髓移植后的追踪观察。中国实验血液学杂志,2001 ;

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In her eyes, because that is the doorway toher heart * the place where love resides.

女人的漂亮必須從她的眼睛中去看,因為那是她心靈的窗戶和愛居住的地方

I will send some postcards to you.

我会向你发送一些明信片。

Of aesthetics and the definiteness of its content and leads to its immaturity and decline .

它的不确定,直接影响美学学科定位乃至研究内容的确定,导致美学学科的不成熟和衰微。