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软骨结构

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Into'.'' cartilage or become cartilaginous.

发展'。''成软骨结构或变成软骨性的

Some cooks also cut off the head, tail, and all "cartilage or gristle." Prepare according to your recipe.

有些厨师会还切掉头部,尾部,和所有的"软骨或软骨结构")最后根据菜谱制作。

Result: Cellular proliferation and ground substance were secreted of the superficial layer articular cartilage by passive movements, and the new fillers were close to the normal articular cartilages.

结果:被动运动最能使浅层部分损伤软骨内的软骨细胞增生及基质分泌,使受损软骨表面的新生填充物接近于正常的软骨结构

Then the content of the interleukin (IL-1) in serum were measured by the method of enzyme-linked assay; From the HE dyeing, the change of morph in the arthrodial was observed by the light microscope; From the AB-PAS dyeing, the change of PG in the cartilage matrix was observed; By all of that the therapeutic efficacy of the medicine wine Yong GuKangNing to the disease of osteoarthritis was estimated, and the mechanisms to the disease was also investigated.

用酶免法测定血清中白细胞介素(IL-1)的含量;常规HE染色,光镜下观察关节软骨结构形态学变化;AB-PAS染色,光镜下观察软骨基质中蛋白聚糖的染色变化;评价永康宁骨康宁对膝骨性关节炎的治疗效果,并探讨其作用机制。

The light microscope observed four-layer structures of arthrodial cartilage, regularly ordered chondrocytes, even chromatin and clear nucleus in normal group. In the model group, the layer of arthrodial cartilage was thinning; chondrocytes in some regions showed karyopyknosis or necrosis with irregular order.

光镜下正常对照组关节软骨四层结构清晰可辨,软骨细胞排列整齐呈柱状,染色质分布均匀,细胞核清晰;模型对照组关节软骨层变薄,部分区域软骨细胞核固缩、坏死,软骨细胞排列紊乱,四层结构不易分辨。

A paradigm for functional tissue engineering of articular cartilage via applied physiologic deformational loading.

课题评估的&金标准&:课题主要结果指标评价是否能有效进行功能化关节软骨结构、功能的构建。

Elastic fibers were well-distributed,and vascular endothelial cell did not immigrate.We suggested that expression of ectogenic VEGF triggered paracrine and autocrine of VEGF of chondrocyte and co-acted with VEGF receptor 2 to enhance permeability of chondrocyte and improve internal construct of engineering cartilage,and prevent vascularize proceed.

转VEGF基因软骨细胞作为组织工程的种子细胞与pluronic F-127复合后可于裸鼠体内形成转基因组织工程软骨,与对照组相比,转VEGF基因组织工程软骨具良好的生物学特性,结构均一且与正常软骨组织相似,软骨ECM的GAG、COLⅡ、COLⅩ增多,RunX2、Sox9表达增高,细胞处于增生期的肥大状态,初步分析其原因可能是转染后外源性的VEGF持续表达触发了软骨细胞VEGF自分泌,并通过VEGFR-2作用于软骨细胞,提高了软骨细胞活性,促进其存活与增殖,但未在软骨组织内引起血管内皮细胞的迁移及小血管形成。

The repair results of defects were observed after 4, 12 and 24 weeks. RESULTS: In experimental group, no obvious new cartilage formation was seen 4 weeks after operation; some new cartilage formation was found after 12 weeks. Histological observation showed that chondrocytes had irregular edge, honeycombing structure and that cartilage cavities formed around the chondrocytes.

结果 实验组术后 4周缺损表面未见明显的新生软骨形成;12周,缺损表面有少量的新生软骨形成,组织学切片上可见软骨细胞呈边缘不规则的,小蜂窝状结构,软骨细胞周围有软骨陷窝形成;2 4周,缺损表面的新生软骨较 4、12周的新生软骨明显,表面光滑,且与周围组织结合紧密,但仍存在部分缺损尚未修复。

We obtained the nasal deformation with three-dimensional reconstruction images and adjusted to separate the images of nasal cartilage, defined the form and structure of nasal deformation. Then we measured 10 cases of adult cadavers nasal alar, lateral and septal cartilage through modern mechanical measuring instruments, to obtain the elastic modulus of above three part structure of nasal cartilage, then to obtain more accurate nasal cartilage elastic modulus data through statistical analysis. At the same time, according to the relevant literature, we obtained nasal soft tissue biomechanical properties, mainly were elastic modulus and Poisson\'s ratio. Finally we established three-dimensional finite element analysis model of unilateral cleft lip nasal deformation, defined the model\'s constraint conditions and carried out biomechanical measurement and analysis of unilateral cleft lip nasal deformation.

将唇裂鼻畸形患者鼻部进行三维重建并调校,分离出外鼻软骨的影像,并对鼻部组织进行分层和重建,确定畸形鼻的形态和组织结构;通过现代力学测量仪器,对10例成人尸体鼻部的大翼、侧鼻和中隔软骨进行弹性模量的测量,获得上述三部分鼻部软骨结构的弹性模量数据,并通过统计学分析来获得较为准确的鼻部软骨结构的弹性模量数据,同时查阅相关文献,得到鼻部软组织的相关生物力学性质,主要为弹性模量和泊松比;建立单侧唇裂鼻畸形的畸形鼻部三维有限元分析模型,确定有限元分析的边界条件等,进行单侧唇裂鼻畸形的鼻部生物力学的测量和分析。

The biomimetic structure of the multilayered scaffold is very close to that of the natural articular cartilage, and the different layers of the biomimetic multilayered scaffolds had different mechanical properties under wet state. These are hopefully beneficial to help maintain the phenotypes of chondrocytes and promote the repairing effect of cartilage defects .

仿生多层软骨支架的结构接近于天然关节软骨多层结构,且在湿润状态下各层的力学性能有差异,有望更好地维持软骨细胞表型和提高软骨损伤修复效果。

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