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Objective: To explore the difference of clinical features and biochemical indices of hypercortisolism among male and female patients with Cushing's disease. Methods: Eighty-one patients (56 females and 25 males)with CD were selected.

手术确诊的库欣病患者81例,根据性别分为男性组25例,女性组56例,比较2组临床症状、影像学检查结果,血、尿皮质醇,血促肾上腺皮质激素,小剂量(1 mg和/或2 mg)及大剂量(8 mg)地塞米松抑制试验的结果。

Pasireotide produced a decrease in UFC levels in 76% of patients with Cushing's disease during the treatment period of 15 d, with direct effects on ACTH release.

治疗15天后,Pasireotide通过直接影响促肾上腺皮质激素释放,使得76%的库欣病患者UFC水平降低。

Secondary hypertension caused by a common endocrine disease mainly with primary aldosteronism, pheochromocytoma, Cushing's disease, congenital adrenal hyperplasia of these four.

引起继发性高血压的常见内分泌疾病主要有原发性醛固酮增多症、嗜铬细胞瘤、皮质醇增多症、先天性肾上腺增生症这四类。

PCI2 cells were treated under glucose deprivation as model group. Method Morphological and cytoflowmetric methods (the mitochondrial transmembrane potential; MEF method) were applied to evaluate the protective effect of SAB. The RNA levels of grp75 were measured by RT-PCR and immunocytochemistry were performed to investigate the expression level of PC12 cells under glucose deprivation and treated by SAB.

以PCl2细胞(大鼠肾上腺嗜铬细胞瘤细胞)的无糖培养建立细胞缺糖损伤模型,MTT法检测细胞的存活率;应用流式细胞仪检测亚二倍体细胞的比率及线粒体跨膜电位的改变;应用免疫细胞化学、RT-PCR法研究细胞内应激蛋白grp75的表达变化,激光共聚焦显微镜观察SAB作用下Ca(上标 2+)的变化。

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Since historical times,England ,where the early inhabitants were Celts, has been conquered three times .

从有历史以来,英国,在此地早期居住的是凯尔特人,已经被征服了三次。

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