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Receiving signals from any kinds of cascades, a number of transcription factors have been implicated as direct mediators of hypertrophic gene expression including SPl, Elk-1, SRF, MEF-2, GATA, and LIM proteins.

目前虽然认为心肌肥大的发病机制与细胞外的心肌肥大因子刺激、细胞内的信号转导和核内的某些基因活化有关,但其最本质的特征是心肌细胞基因表达的异常。

Results The results showed that the number of mast cells around the periphery of gingival cancer tissue increased significantly.

结果 在牙龈癌周围组织中肥大细胞显著增多,在组织化学上与正常牙龈组织的肥大细胞不同,不含肝素。

The inframammary scar length was less than 8.5 cm. Conclusion Marchac's procedure is suitable for patients with moderate hypermastia. It is easy to get a good steady shape and short scar. A satisfied result will also be obtained through controlling the thickness of gland flaps carefully during the operation and taking proper treatment for the patients postoperatively.

Marchac法治疗中度乳房肥大具有效果持久,外形好,瘢痕短等优点;对于重度肥大的乳房,通过控制术中腺体瓣的厚度及配合术后积极处理,也可取得满意的治疗效果。

Immunofluorescence staining shows that, the CaN Aβ protein expression of intrapericardial injection group decreased in some myocytes under epicardium, while other groups show no decreased fluorescence.

三在体心肌CaN AβsiRNA表达质粒转染后,转染各组与心肌肥大模型组CaN AβmRNA水平比较无差异(P>0.05),但免疫荧光结果显示心包腔内途径CaN Aβ干扰组较心肌肥大模型组心外膜下部分心肌荧光减弱。

Results:Compared with model group,the mast cell number of three Iridoids composition of Valeriana jatamansi Jones groups have a trend of reduce,but the result have no statistically significance.

结果:造模后,模型组较对照组肥大细胞明显增多,与模型组比较,蜘蛛香环烯醚萜各组结肠粘膜固有层及粘膜下层血管周围肥大细胞数量减少。

Patients with extraocular muscles thickening and 3 patients with tendon involvement 16 patients with orbital lipotrophy 3 patients extraocular muscles thickening accompany by superior ophthalmic vein enlargement. 1 patients extraocular muscles thickening accompany by optic never thickening 2 patients extraocular muscles thickening accompany by lacrimal gland augmentation 39 patients with eyelid swelling.

结果 58例甲状腺相关性眼病眼球突出CT影像观察,单纯眼外肌肌腹肥厚(n=54,肌腹及肌键、肌止点均受累及(n=3);眶脂肪增多(n=16);眼外肌肥厚伴眼上静脉增粗(n=3);眼外肌肥大伴视神经增粗(n=1);眼肌肥大伴泪腺增大(n=2);眼睑肿胀(n=39)。

Less postmenopausal subjects than premenopausal subjects had cervical Nabothian cysts and hypertrophy, while postmenopausal subjects had more cervical erosions. On the other hand the positive detection rate of cervical smears above second level in 30-49, 50-54 and 55-59 years of age groups were fewer than other groups.

其中,已绝经者宫颈纳氏囊肿、宫颈肥大和宫颈糜烂的检出率均低于未绝经者;30~49和50~54岁组宫颈纳氏囊肿和宫颈肥大检出率较高;而30~49、50~54和55~59岁组宫颈涂片≥Ⅱ级的检出率较低。

PDTC inhibit the NFkB binding activity and the level of phospho- GSK-3β(Ser9) in hypertrophic heart tissues and thereby attenuates the development of cardiac hypertrophy.

为此,本研究以压力负荷增加诱导的小鼠心肌肥大为模型,进一步探讨PDTC抑制NF-κB活性的机制,并观察PDTC对心肌肥大发生发展的影响。

Many tumor specific antigens such as mouse PlA, human MAGE, BAGE and GAGE families had been isolated during recent decade. PlA is a tumor specific antigen expressed by mouse mastocytoma P815. It is one kind of cancer-testis antigens and expresses in various mouse tumor such as mastocytoma P815, plasmoma J558 and fibrosarcoma Meth A but hardly in normal tissue except testis and placenta.

近十年来已经成功分离出多种鼠或人的肿瘤特异性抗原,如小鼠P1A基因和人的MAGE、BAGE、GAGE家族等。P1A为小鼠肥大细胞瘤P815所表达的肿瘤特异性抗原,它是一种CT抗原,在多种小鼠肿瘤如肥大细胞瘤P815、浆细胞瘤J558和纤维肉瘤Meth A等中表达,而在除睾丸、胎盘之外的正常组织中不表达。

In this study, we observed the effect of mast cell tryptase on cultured human renal interstitial fibroblasts, so as to further investigate the effect of tryptase on renal fibrosis.

本实验研究肥大细胞类胰蛋白酶及蛋白水解酶抑制剂苯甲脒(benzamidine hydrochloride hydrate,BZ)对人肾成纤维细胞的影响,以探讨肥大细胞类胰蛋白酶在肾纤维化过程中的作用。

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