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肝内胆管结石

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Results: According to position of stones and intrahepatic bile duct stricture, 26 cases were treated by hepatectomy or combined hepatobiliary basin drainage.

结果 26例患者根据结石部位及胆管狭窄情况的不同,采用了不同的肝段切除或联合肝胆管盆式内引流术式。

Results 20 cases of CT examination had made proper diagnoses,the CT imaging finding about the most of peripheral cholangiocarcinoma included:There was the atactic low density tumour in liver,its borderline was unclear,enhanced scan appearances were irregular peripheral enhancement,centripetal enhancement,and delaying enhancement;There was concretion and dilatation of bile buct in or around the focus;The local envelope of liver was lacunose and the local liver was atrophied,There was abroad putrescence and liquescence in the focus.

结果 20例CT做出了正确的诊断,大部分周围型胆管细胞癌的CT表现为肝内不规则低密度肿块边界欠清,增强扫描表现病灶边缘呈不规则环状强化,有向心性强化的趋势,出现延迟强化;病灶内或周围可见结石,病灶内及周围肝内胆管扩张;局部肝包膜回缩、肝叶萎缩,病灶内大片坏死、液化。

Cholesterol gallstones formed in C57L mice and fatty livers developed in AKR mice. Conclusions Biliary cholesterol hypersecretion is the key pathophysiological defect of gallstone formation, lith genes have effects on biliary cholesterol hypersecretion and susceptibility to cholesterol gallstone formation in C57L mice. Lithogenic bile is formed at the canalicular membrane and precedes the development of cholesterol gallstones. It is most likely that cholesterol and bile acid hyposecretion make the AKR strain susceptible to the development of fatty livers and resistant to gallstone formation.

结论胆道胆固醇的高分泌是胆囊胆固醇结石形成的主要病理生理基础,结石基因决定了C57L鼠肝内胆汁中胆固醇的高分泌和胆囊胆固醇结石的易患性,成石胆汁形成在肝内胆管,先于胆囊结石的形成;肝内胆汁中胆固醇和胆酸的低分泌可能与AKR鼠脂肪肝的发生和胆囊结石的免患性有关。

Results All patients underwent percutaneous cholecystostomy with technical success without major periprocedural complications. 93 (96%) patients responded well clinically showing disappearance of right upper abdomen pain and fevers within 72hr. 4 patients complicated with common bile duct stones were underwent PTCD one day after the procedure because of no response clinically. After PTCD, all 4 patients attained clinical symptom relief within 72hr.

结果 所有97例患者均一次置管成功,无任何并发症。93例(96%)患者临床体征如右上腹疼痛、发热在72h内缓解;同时,血常规中的WBC及中性粒细胞均于72h内降至正常范围。4例患者由于肝总管内结石合并胆管炎临床症状缓解不明显而于第2天行经皮肝穿胆管引流术,术后临床症状于72h内亦缓解。

One hundred and fifty patients with intrahepatic stone were operated on during the past 20 years.

在过去20年中,为150例肝内胆管结石的病例施行了手术,全有胆道感染的病史。

Objective To study the etiology of primary intrahepatic stones.

目的 了解原发性肝内胆管结石的形成原因。

Results 20 cases of CT examination had made proper diagnoses,the CT imaging finding about the most of peripheral cholangiocarcinoma included:There was the atactic low density tumour in liver,its borderline was unclear,enhanced scan appearances were irregular peripheral enhancement,centripetal enhancement,and delaying enhancement;There was concretion and dilatation of bile buct in or around the focus;The local envelope of liver was lacunose and the local liver was atrophied,There was abroad putrescence and liquescence in the focus.

结果 20例CT做出了正确的诊断,部分周围型胆管细胞癌的CT表现肝内不规则低密度肿块边界欠清,增强扫描表现病灶边缘呈不规则环状强化,有向心性强化的趋势,出现延迟强化;病灶内或周围可见结石,病灶内及周围肝内胆管扩张;局部肝包膜回缩、肝叶萎缩,病灶内大片坏死、液化。

Among the 6 cases with dilated biliary tract, biliary sludge were seen in 4 cases(biliary stone existed simultaneously in 2 cases). Biloma were observed in 2 and the echogram of acute rejection was misdiagnosed as biliary sludge in one case.

结果:19例肝移植术后患者超声检查显示胆管弥漫性病变9例,胆管扩张的6例中有胆泥4例(2例伴胆管结石);将急性排斥反应误诊为胆泥1例;伴肝内胆汁脓肿2例。

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