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组织细胞

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Between P14 and P21,CIAPIN1 immunoreaction in the brain,heart and liverbecame much lower. However,between P21 and P28,CIAPIN1 immunoreactionin the heart,brain,liver and skeletal muscle became much lower,while with thekidney development,CIAPIN1 immunoreaction in the kidney became higher. Invarious tissues from adult mouse,CIAPIN1 immunoreaction could be seen incardiac muscle cell,brain,hepatocyte,epithelium of renal tubule,skeletal muscle,lung tissue,gastric mucosa and gland,acinus lienalis.2. Distribution of CIAPIN1 in normal fetal and adult human tissuesTo reveal the possible physiological role of CIAPIN1,we examined theexpression and distribution of CIAPIN1 in fetal and adult human tissues usingimmunohistochemistry. We found that CIAPIN1 was ubiquitously distributed infetal and adult tissues,and was localized in both the cytoplasm and the nucleus.

然而,在3个月大的成年鼠中,CIAPIN1阳性反应物在心、脑、肝和肾小管中的表达强度要低于P28小鼠;但CIAPIN1阳性反应物在成年鼠骨骼肌中较P28小鼠高。2、CIAPIN1蛋白在人5个月胚胎及成人多器官组织内的表达在人5月胚胎多器官组织中,CIAPIN1阳性反应物见于心脏、胆囊单层柱状上皮和粘膜、结肠粘膜、小肠粘膜和绒毛、肝脏、直肠腺体、胃粘膜、肾上腺束状带、甲状腺滤泡、脾索、胸腺小叶间隔、皮肤真皮层和汗腺、睾丸白膜和间质、脑组织内神经元和神经胶质、肺小支气管和肺泡、骨骼肌、肾脏皮髓质和肾小管、子宫内膜、胰腺腺泡和胰岛、卵巢、输卵管粘膜等绝大多数组织细胞

On the basis that Panax Tonifying Soup Mix can effectively improve and postpone cytoarchitecture impairment in hepatic and brain tissues in subacute senile mice, in order to approach the dependablity between postponing anaplasia of senile tissue cells and the ability of cleaning oxygen free radicals, lipid peroxidatic conditions, degree of cell injury of the recipe-medicine, serum SOD activity and MDA content were selected as quantitative indexes for objectively evaluating the antioxidation of this recipe-medicine.

在明确人参养荣汤有效改善、延缓D-半乳糖所致亚急性衰老鼠肝、脑组织与细胞结构损伤的基础上,为探讨该方药延缓衰老组织细胞退行性改变与清除氧自由基能力、脂质过氧化状态,细胞损伤程度的相关性,选择血清SOD活性、MDA含量作为定量指标,旨在对该方药抗氧化作用给予客观地评价。

Debris necrosis of lymph node is not the specific changes of KD. In the tuberculosis of lymph node,① debris necrosis is obvious, but it tends to be caseous nercrosis;② histiocytes, macrophages and foam cells are hyperplasia in the necrotic area or lymph sinus, moreover, epithelioid cells can be found and they tend to be form granuloma;③ numbers of neutrophils infiltrate in the necrotic area;④ the etiologic assay of acid fast bacterium tuberculosis bacterium is positive;⑤ typical clinical manifestation is insufficient.

淋巴结碎屑性坏死并非KD特有病变,诊断KD需先除外有明显碎屑性坏死的淋巴结结核病,后者主要表现:①碎屑性坏死虽明显,但趋于干酪样坏死;②坏死区内或同时在淋巴窦内,组织细胞、巨噬细胞和泡沫细胞增生,并演变为上皮样细胞和趋于肉芽肿形成;③坏死灶内、外可有数量不等的中性粒细胞浸润;④抗酸杆菌/结核杆菌病原学检测阳性;⑤缺乏KD的典型临床过程。

Although we did not identify which cells were undergoing apoptosis,47 others50 51 52 have reported increased numbers of lung structural cells undergoing apoptosis in emphysematous lungs.

尽管我们无法确定是何种细胞进行细胞凋亡,但是已经有报道指出气肿型的肺部内,数目增多的肺部组织细胞进行着细胞凋亡。

E studied expression levels of WAVE1 in six leukemia cell lines (the human Jurkat T leukemia cells, U937 histiocytic lymphoma cells, Burkitts lymphoma cell Raji, acute promyelocytic leukemia cell HL-60, chronic myelogenous leukemia cell K562 and K562/A02) by Western blotting analysis. Levels of WAVE1 expression were high in all six human leukemia cancer cell lines. In contrast, the constitutive expression levels of WAVE1 were noticeably lower in normal human peripheral blood mononuclear cells, or non-blood cancer cell-lines, including human lung A549 cancer cells, Hela cervical cancer cells, MG-63 osteosarcoma cells, CNE2 nasopharyngeal carcinoma cells, human umbilical vein endothelial cell, QSG7701 hepatocarcinoma cells, and WI-38 lung fibroblastoma cells.

AVE1在人类血液肿瘤细胞系(人T细胞白血病细胞系Jurkat、人组织细胞淋巴瘤细胞系U937、人Burkitts淋巴瘤细胞系Raji、人原髓细胞白血病细胞系HL-60、人慢性髓原白血病细胞系K562和K562/A02)中高表达,在非血液肿瘤细胞系(人肺腺癌细胞系A549、人宫颈癌细胞系Hela、人成骨肉瘤细胞系MG-63、人鼻咽癌细胞系CNE2、人脐静脉内皮细胞系HUVEC、人肺成纤维细胞系WI-38、人肝上皮细胞系QSG7701)以及正常人外周血单个核细胞中低表达或不表达。

BACKGROUND: The histocyte and inflammatory cells played an important role in the invasion and metastasis of lung cancer cells. However, cell interaction influenced matrix metalloproteinase.

摘要背景:组织细胞、炎细胞可能在肿瘤细胞的侵袭、转移中发挥着重要作用,而细胞间的相互作用对基质金属蛋白酶有影响。

When pea ( Pisum sativum L.,Alaska strain) was grown in short\|day conditions,the apical bud senescence started with the transformation of the bud from vegetative to reproductive growth.DNA fragmentation was detected during the senescence using the terminal deoxynucleotidyl transferase\|mediated dUTP nick end in situ labeling method.The cell ultrastructural changes were similar to apoptosis in animal cells:the apical meristemetic cells underwent the programmed cell death.This wa...

显微、超微结构研究表明,短日照条件下豌豆顶芽的衰老过程是从营养生长锥向花芽的转化,而用DNA原位末端标记、Caspase 8WesternBlot和 14 0bpDNA片断积累的试验结果证明,转化为花芽的整个生长锥细胞发生了编程性死亡,而且其最顶端部分细胞首先发生PCD ,而顶端周围的分生组织细胞逐渐分化出花芽的各部分,但顶芽最后并没有发育成为完整的花,所有细胞就都发生PCD ,从而顶芽衰老

The results showed that PCD was initiated in the tapetal, chalice, and connective cells during tetrad stage after mitosis of the anther tissue cells; however, anther vascular tissues underwent PCD during microspore mother cell stage.

结果表明绒毡层、环形细胞、药隔组织细胞在减数分裂后四分体时期开始出现PCD,而花药维管束细胞从小孢子母细胞时期就开始出现PCD。

Once delivered to the heart, injected cells are difficult to distinguish from target tissue by MR in vivo.To specifically imaging injected cells in MR, the recent investigation generally using superparamagnetic iron oxid to label MSCs, which should enable serial tracking and quantification of MSC transplantation noninvasively by MR.

由于MR成像无法区分移植细胞和靶组织细胞,为使移植细胞能在MR上特异性显示,目前广泛使用超顺磁性氧化铁(superparamagnetic iron oxid, SPIO)作为负性标记物标记移植细胞,进行MR体外和活体内的成像研究。

The expression of HSP70 and HSP70mRNA and the activity of SOD and NOS in uterus were elevated with preventive acupuncture and preventive moxibustion and the influence on the activity of SOD and NOS was mainly refected in 12th and 16th month. It indicated that preventive acupuncture and preventive moxibustion on Guanyuan point could relieve the abnormal activity of center of stress, promote the expression of HSP70 and HSP70mRNA and the activity of SOD and NOS in uterus so as to maintain the normal structure and function and prolong the retrograde degeneration of uterus. It might be one of mechanisms of protecting uterus with preventive acupuncture and preventive moxibustion.

提示逆针灸关元穴对随后更年期大鼠子宫产生保护作用机制可能通过减缓应激中枢的异常活跃状态,提高不同月龄外周子宫组织细胞HSP70及mRNA的表达,以促进组织SOD、NOS活性的增强,对抗应激激素及卵巢功能衰退引起的子宫靶器官的结构及功能的改变,提高机体抗氧化能力,增强NO/NOS的局部调节作用,减轻随后更年期衰老过程中自由基对组织器官的损害及组织器官功能紊乱,对于维持子宫正常的结构和功能,延缓子宫退行性变具有重要作用。

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