瘤

Hybrid schwannoma/perineuriomas have no evident association with neurofibromatosis and rarely recur. The pathogenetic basis of the dual pattern of differentiation in these lesions remains poorly understood at this time.

混合性神经鞘瘤/神经束膜瘤与神经纤维瘤病无明显关系，且罕有复发，其瘤组织双重分化的发生机制目前仍不清楚。

EMA was the most effective antibody for differentiating chordoid meningioma from skeletal myxoid chondrosarcoma, low-grade chondrosarcoma, and enchondroma, whereas D2-40 was the most effective antibody for differentiating chordoid meningioma from extraskeletal myxoid chondrosarcoma and chordoma.

EMA是鉴别脊索样脑膜瘤和骨的黏液样软骨肉瘤、低级别软骨肉瘤、内生性软骨瘤最有效的抗体，而D2-40则是鉴别脊索样脑膜瘤和骨外黏液样软骨肉瘤、脊索瘤最有效的抗体。

Results Among 85 cases, 46 cases were lipomas, Twenty-seven cases were sebaceous cysts, 19 cases were angeiomas, 8 cases were fibroids, 5 cases were ganglionic cysts, 3 cases were neurilemmomas,1 case was dermal nevus, 1 cases was fattey necrosis, 1 case was adipositis, 1 case was foreign-body granuloma,1 case was calcified epithelioma.

结果 85例中脂肪瘤46例，皮脂腺囊肿27例，血管瘤19例，纤维瘤8例，腱鞘滑液囊肿5例，神经鞘膜瘤3例，皮肤痣、脂肪坏死、脂膜炎、异物肉芽肿、钙化上皮瘤各1例。

To date,it has been documented after transfusion of unirradiated blood components to at least 87 patients:in patients with severe combined immunodeficiency,thymic hypoplasia,and Wiskott Aldrich syndrome premature newborns and those with erythroblastosis fetalis; patients with hematologic malignancies including Hodgkin\'s and non-Hodgkin\'s lymphomas,acute myelocytic and lymphoblastic leukemias,chronic lymphocytic leukemia,and aplastic patients with solid tumors including neuroblastomas, glioblastoma,rhabdomyosarcoma,cervical carcinoma,small cell lung cancer,and germ cell tumor;patients after cardiac surgery and cholecystectomp-60;and in an apparently healthy 22-year-old woman.

目前为止，输注未辐照血液成分后，至少引起了87例TA-GVHD的发生，主要见于以下病人：严重的免疫缺陷病人、胸腺发育不全、Wiskott Aldrich综合症、早产儿、胎儿红细胞增多症、何杰金与非何杰金氏淋巴瘤等恶性血液病人、急性粒细胞性和淋巴细胞性白血病、慢性淋巴细胞性白血病、成神经细胞瘤等实体瘤病人、横纹肌赘瘤、宫劲癌、小细胞肺癌、微细胞瘤、心脏和胆囊手术病人。

Prepare 131I-labbelled anti-CD20 monoclonal antibody using lodogen iodine labelling;(2)Measure the immunity activation of labbelled antibody by means of both cell combine analysis and LDH cytotoxicity detection kit;(3)Evaluate the injury rate of tumor exposed to 131I-chimeric anti-CD20 monoclonal antibody in vitro. The MTT method and the experiment of cell growth control are used;(4)Record the apotosis of Daudi cell using gelose electrophoresis;(5)Learn the inhibition effect of radioactive medication on the marrow. Radiohnmunoimages are taken on various intervals after injection of the labeled antibodies to the nude mice. The distribution of radioactive medication, I31l-labeled antibodies, in the marrow tissue indicates the inhibition effect. Here a B cell non-hodgkin lymphoma model in nude mice is established by us;(6)28-day observation are done in 3 groups of nude mice model.

(1) 用lodogen标记法制备131I-国产人鼠嵌合抗CD20单抗；(2)采用细胞结合分析法和乳酸脱氢酶法细胞杀伤性实验测定131I标记后国产人鼠嵌合抗CD20单抗与靶细胞的免疫活和利结合能力；(3) MTT法和细胞生长抑制实验测定131I-国产人鼠嵌合抗CD20单抗的体外杀瘤活性；(4)用琼脂糖凝胶电泳法研究131I-国产人鼠嵌合抗CD20单抗致Daudi细胞凋亡；(5)建立荷人B细胞淋巴瘤移植瘤裸鼠模型，应用γ计数法检测注射到荷瘤裸鼠体内的131I-国产人鼠嵌合抗CD20单抗的组织分布情况，明确其靶向性；(6)将荷瘤裸鼠分3组进行放射免疫治疗，分别为阴性对照组、131I-国产人鼠嵌合抗CD20单抗组、国产人鼠嵌合抗CD20单抗组。

Methods:35 cases of otic neoplasms confirmed by clinic and biopsy, including 16 cases of acoustic neuroma, 3 cases of facial nerve neuroma, 10 cases of glomus jugulare tumor, 3 cases of carcinoma of middle ear, 3 cases of congenital cholesteatoma.

35例经临床病理证实的耳部肿瘤，其中听神经瘤 16例，面神经瘤 3例，颈静脉球瘤 10例，中耳癌 3例，先天性胆脂瘤 3例，全部病例均行CT检查，根据需要部分病例行MRI检查。

Methods:35 cases of otic neoplasms confirmed by clinic and biopsy, including 16 cases of acoustic neuroma, 3 cases of facial nerve neuroma, 10 cases of glomus jugulare tumor, 3 cases of carcinoma of middle ear, 3 cases of congenital cholesteatoma. All cases had CT examination and some of them had MRI examination when needed.

35例经临床病理证实的耳部肿瘤，其中听神经瘤16例，面神经瘤3例，颈静脉球瘤10例，中耳癌3例，先天性胆脂瘤3例，全部病例均行CT检查，根据需要部分病例行MRI检查。

Results: CT diagnosis before surgery revealed 16 mastoiditis of simple type 8 of granullomatous type and 18 of cholesteatoma type.All the 26 cases of granullomatous and cholesteatoma type were operated on, but 2 cases were cholesteatoma type in 8 cases of granullomatus type and 3 were granullomatus type in 18 cases of cholesteatoma type.

术前诊断单纯型16耳，肉芽肿型8耳，胆脂瘤型18耳。26耳诊断为肉芽肿型和胆脂瘤型患者均行手术治疗，术前诊断为肉芽肿型8耳，术后2耳病理证实为胆脂瘤型。18耳胆脂瘤型术后证实有3耳为肉芽肿型。

Giant cell tumor of bone is a kind of common bone tumor,which has characteristics of high recurrence rate and invasion.recently,tumor vessel angiogenesis has been the warm spot of research.genesis,development and metabasis of solid tumor have close relationship with tumor vessel angiogenesis; extracellular matrix degradation is the key point for tumorous infiltration and metabasis;the significant biology characteristic of tumor cell is the disorder of tumor cell differentiation and apoptosis.the correlated research has very important significance for judging gct prognosis and guiding therapy.

骨巨细胞瘤（giant cell tumor of bone，gct）是一种常见骨肿瘤，由于其高复发率和强侵袭性，备受临床骨科工作者的关注。骨巨细胞瘤血管生成是近年来研究热点，实体瘤的发生、发展及转移与肿瘤的血管生成密切相关；细胞外基质降解在肿瘤的浸润和转移中起到关键作用；肿瘤细胞的分化凋亡障碍与无限增殖能力是肿瘤细胞的重要生物学特征。骨巨细胞瘤生物大分子研究的不断深化对判断gct的预后及指导治疗有重要意义。

Results There were medulloblastoma in 7cases,astrocytoma in 7 cases,ependymoma in 3 cases and nerve fiber tumor in 1 case.

结果检出髓母细胞瘤7例，星形细胞瘤7例，室管膜瘤3例，神经纤维瘤1例。

He is the most remarkable man that I have ever known.

他是我知道的人中最值得注意的人。

Increased appearance of lymphocele was noticed in patients with diabetic nephropathy, congenital malformations of the urinary tract, and inflammatory diseases, including glomerulopathy and extraglomerular ones, after high-voltage radiotherapy and after removal of the renal graft.

经过高压放射疗法和切除移植肾后，在糖尿病肾病患者、泌尿系统先天性畸形患者和炎症患者身上发现淋巴囊肿有所增加，包括肾小球病和球外疾病等。