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In 1989 it was finally approved by the FDA to treat eye muscle disorders; these included blepharospasm, strabismus and even wrinkles.

在1989年,它终于被批准了FDA的治疗眼肌障碍;这些措施包括眼睑痉挛,斜视,甚至是皱纹。

Currently Botox has approval to treat medical disorders such as blepharospasm, cervical dystonia and cerebral palsy.

肉毒素目前已经批准治疗医疗紊乱,如眼睑痉挛、颈肌张力障碍、斜视和大脑中风和偏头痛。

After adjusting for age, sex, disease duration, and other potential confounders, prior coffee intake was associated with a 56% to 63% reduced risk of blepharospasm, lead author Dr. Gioanni Defazio, from the Uniersity of Bari in Italy, and colleagues note.

在调整年龄、性别、疾病时间和其他混杂因素后,预先摄入咖啡可减少睑痉挛风险56%-63%,第一作者意大利巴里大学的Gioanni Defazio博士和他的同事指出。

Blepharospasm is often associated with other tics such as hitching up a shoulder, jerking up the chin, or turning or tilting the head to one side.

眼睑痉挛,往往与其他相关的TICS资本流动,如hitching了一个肩膀, jerking了下巴,或转折或倾斜头部向一边倾斜。

NEW YORK - Daily coffee intake is inersely associated with the risk of primary late onset blepharospasm, a common type of late-onset dystonia, new research suggests.

路透社纽约报道——一项新的研究显示,每天饮用咖啡可逆转原发性睑痉挛的发作风险,一种常见迟发性肌张力障碍。

The researchers speculate that caffeine may protect against blepharospasm by blocking adenosine receptors, a mechanism that has also been proposed for its possible preentatie effects on Parkinson's disease.

研究者推测咖啡因通过阻断腺苷受体,一种仍被认为可能有预防帕金森氏症作用的机制,来保护对抗睑痉挛

Methods:33 cases (35 eyes) in patients with blepharospasm,the use of compound anisodine 1ml,vitamin B12 injection 500μl,2% procaine 0.3ml,mixed,suffering from eye side of the superficial temporal artery peri eyelid subcutaneous injection.

对33例(35眼)眼睑痉挛患者,使用复方樟柳碱1ml、维生素B12注射液500μl、2%普鲁卡因0.3ml,混合,患眼侧颞浅动脉旁及眼睑皮下注射。

Botulinum toxins were first researched in the late 1960s to treat neurological disorders and for that otox were first approved by the FDA in 1989 to treat eye muscle disorders like blepharospasm, uncontrollable blinking, and strabismus, crossed eyes.

肉毒毒素的研究,首次在六十年代后期治疗神经系统疾病,并为此otox首次核准由美国食品暨药物管理局在1989年治疗眼部肌肉疾病如眼睑痉挛,无法眨眼,斜视,眼划线。

Botulinum toxins were first researched in the late 1960s to treat neurological disorders and for that otox were first approved by the FDA in 1989 to treat eye muscle disorders like blepharospasm, uncontrollable blinking, and strabismus, crossed eyes and even for wrinkles.

肉毒毒素的研究,首次在六十年代后期治疗神经系统疾病,并为此otox首次核准由美国食品暨药物管理局在1989年治疗眼部肌肉疾病如眼睑痉挛,无法眨眼,斜视,越过眼睛,甚至皱纹。

Results Women were more often affected than men(1.83:1) and 53 patients were older than 40 years. The involved parts were as follows: eyelid 58 cases (89.2%), mouth and mandibula 46 cases(70.8%),neck 17 cases(26.2%). The symptom at onset were blepharospasm 42 cases(64.6%) or oromandibular dystonia 17 cases(26.2%).In part of the patients, cranial MRI examination could find focus in brainstem or basal ganglia. Among 37 patients treated with oral drugs, 4 cases were almost cured, 16 cases improved and 17 cases showed no effect. While in 15 patients treated through chiostridium botulinum toxin injection, 5 were almost cured, 9 improved and 1 had no effect.

结果 男女患病比率 1:1.83,40岁以上发病53例,受累部位依次为眼睑58例(89.2%)、口-下颌46例(70.8%)、颈部17例(26.2%);首发症状以眼部不适、眼睑痉挛最(42例,占64.6%),口-下颌肌张力障碍次之(17例,占26.2%);14例行头MRI检查者8例发现脑干或基底节区病灶;口服药物治疗37例,显效4例,有效16例,无效17例;15例行肉毒毒素局部注射者显效5例,有效9例,无效1例。

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