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Differential expression of IGF-I in muscles of mastication during distraction osteogenesis of mandible in canine.This study was conducted to observe the expression of IGF-I in masseter and geniohyoid during distraction osteogenesis of mandible in canine through the immuno-histocytochemical method.

试验三犬下颌骨张成骨过程中咀嚼肌IGF.I的表达变化将所取标本进行免疫组化染色,检测犬下颌骨张成骨过程中嚼肌与颁舌骨肌中IGF.I表达的变化。

In this experiment, in the way of observing the histological changes, relative content of myosin heavy-chain mRNA and changes of the expression of IGF-I in masseter and geniohyoid muscle during distraction osteogenesis of canines mandible, we can learn about the rebuilding ability of masticatorymuscles and its changing regularity, and preliminarily discuss its remodeling mechanism.Anteroposterior bilateral distraction osteogenesis was performed on 14 mongrel canines, 6 to 8 months of age, using intraoral mandibular distractor.

本实验通过观察犬下颌骨张成骨过程中嚼肌与颏舌骨肌的组织学变化、肌球蛋白重链亚型mRNA含量以及IGF-I在咀嚼肌中表达的变化,了解张成骨过程中口颌肌肉的改建能力及其变化规律并初步探讨其改建机制。

To establish an experimental dog model of vertical alveolar distraction osteogenesis using intraosseous distractors which were developed by ourselves.

应用自行研制的骨内型牙槽骨张器,建立犬垂直向牙槽骨张成骨动物模型。

Method]from january 2003 to may 2006,32 patients were corrected with qin si-he's orthotics devices on the ilizarov principle of tension-stress,which involved 15 males and 17 females,the age ranged from 10 to 25 years.among these patients,2 were caused by peroneal nerve injury,l by tumor in the vertebral canal,5 by meningocele,11 were caused by poliomyelitis,13 by congenital talipes equino-varus.in accordance with deformities,external fixator and limitied operative methods were dertermined.the limited release of soft tissue were performed in 7 patients,limited osteotomy in 25 patients.the dynamic muscle balance operation were performed in 9 patients with imbalance of muscle strength.according to the ilizarov technique,the fixative rods were installed.the telescopic rods on the apparatus were rotated one week after the operation,the divices had corrective function in three-dimensional directions.the deformity of talipes equinovarus,internal rotation and drooping of the forefoot were gradually corrected,and the patients could bear weight and walked on the deformed foot.the mean duration of traction were 42 days,then removed the external fixator maintained with plaster for a site time.

方法]2003年1月~2006年5月,根据ilizarov张力应力法则,应用秦泗河改良的外固定矫形器,遵循ilizarov穿针固定的基本原则,共手术治疗马蹄内翻足32例,男15例,女17例;年龄10~25岁,平均17岁。病因:腓总神经损伤2例,腰椎管内肿瘤1例,硬脊膜膨出5例,小儿麻痹后遗症11例,先天性马蹄内翻足13例。术前用足掌的前外缘负重行走者11例,用足的外缘或足背外侧负重者21例。根据马蹄内翻足畸形程度、性质和患者年龄,确定实施有限矫形手术的方法和外固定矫形器治疗。本组7例同期实施有限的软组织松解术,25例同期实施了有限的截骨术和跗骨间关节融合术,9例合并踝关节内外翻肌力明显失衡者,同期行足部肌腱转移的肌力平衡术。然后安装外固定矫形器。术后按作者制定的管理程序,7 d开始旋转相应的螺纹拉杆,对器械进行三维空间的缓慢调整,先矫正前足内收和后足内翻,后矫正足下垂畸形,直至达到矫形要求的标准。在矫形的过程中定期进行x线检测,以防止发生踝关节前后移位,治疗期间允许患足负重行走。术后平均伸42 d,拆外固定器后患足再上石膏固定适当时间。

In my study, a three-dimensional finite element model of human cranial-maxillary complex osteodistraction was established. The stress distribution and displacement under different loads were evaluated. The experiment results were feasible and effective to the stress analysis in the process of orthodontic and orthognathic treatment.

本实验通过建立颅上颌复合体三维有限元模型,分析上颌骨LeFort Ⅰ型截骨后张成骨的生物力学特性,明确在不同引方向时上颌骨复合体各部位的应力分布特点及位移趋势,为临床改良和优化颅面部张成骨的治疗方案提供一定的参考依据。

Effects of mechanical strain on proliferation and differentiation of Saos-2 osteoblastic cells Objective: To investigate the effects of mechanical strain on proliferation and differentiation of Saos-2 osteoblastic cells.

机械张应力对成骨细胞增殖和分化的影响目的:研究机械张应力对成骨细胞增殖和分化能力的影响。

C. Eleate subperiosteally the flexor digitorum longus muscle distally and laterally and the popliteus muscle proximally and medially and expose the posterior surface of the proximal fourth of the tibia Fig.

将趾长屈肌向外下方,做骨膜下剥离,同法剥离腘肌并向内上方,即可显露胫骨近端1/4的后面(图1-37D)。

C. Elevate subperiosteally the flexor digitorum longus muscle distally and laterally and the popliteus muscle proximally and medially and expose the posterior surface of the proximal fourth of the tibia Fig.

将趾长屈肌向外下方,做骨膜下剥离,同法剥离腘肌并向内上方,即可显露胫骨近端1/4的后面(图1-37D)。

Retract the semitendinosus proximally and medially and the gastrocsoleus component distally and laterally; the popliteus and flexor digitorum longus muscles lie in the floor of the interal Fig.

将半腱肌向内上方,腓肠肌向外下方,在间隙底部可见腘肌和趾长屈肌(图1-37C)。

On March 7th, accompanied by Handson Chengdu, Directors from Handson Shanghai, Sparch and the Chairman of The Blackford Trust came a long way to attend the inauguration of Community Flower Project in Xiezi Village, Chong Zhou, Si Chuan.

3月7日,远道而来的手上海负责人, Sparch 设计公司董事及其夫人和The Blackford Trust 主席在手成都的安排与陪同下重返崇州薤子村,与当地政府官员一同参加了心灵之花项目的落成典礼。

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