患者

Results Analysis of the expression of proteins of JAK2 in leukemic blasts, there was no detectable constitutive expression of phosphorylated JAK2 in all the AML samples analyzed; Furthermore, we could detect a constitutive activation of STAT 3 by immunoprecipitation of the targeted protein in primary leukemic blasts from 3 of 11 AML patients without any cytokine treatment; Pretreatment clinical characteristics, and treatment regimens did not differ significantly between patients with and without constitutive STAT3 activity, there was not significant relation between the constitutive activation of STAT3 and the FAB subvariety and chromosome karyotype; However, the 3 patients with constitutive STAT3 activity seemed to have adverse treatment outcome, one did not show remission, the other two patients relapsed shortly after remission; Consistent with the above-mentioned result, leukemic blasts from the 3 samples with constitutive expression of STAT3 showed higher percentage of spontaneous apoptosis and S-phase cells.

在实验研究基础上，本研究进一步运用免疫沉淀和Western Blot印迹方法，检测AML患者原代细胞JAK2和STAT3活化情况，并分析了STAT3活化与AML患者预后有关指标改变的关系。结果我们的初步研究发现，11例AML患者中，有3例呈现STAT3组成型活化（STAT3阳性，下同），无一例呈JAK2组成型活化。上述3例STAT3组成型活化与FAB分型和染色体核型改变未见明显相关性；在此3例患者中，1例未取得缓解，另外2例虽然取得短暂缓解，但均在二个月内复发。上述3例STAT3阳性AML患者S期白血病细胞百分率数值较组高，而凋亡率数值较低。

objective the purpose of this study was to summarize our experience of the application of internal rigid fixation with miniplate to treatment of mandibular fractures.methods a retrospective analyisis of clinical data of 67 cases,who had experienced the anatomic reduction and rigid fixation by using miniplate.with the help of maxillomandibular distraction pre operation and post operation and temporary maxillomandibular fixation during operation,the fracture bones were smoothly reduced and fixed.results clinical and radiographic examination showed that all cases gained good clinical results and precise anatomic alignment of fracture postoperatively without infection,malocclusion,bone malunion or other complications.conclusion mocortical miniplate fixation of the mandible is a reliable and effective techinique providing rigid fixation and an ideal modality for the treatment of mandibular fractures.combined with maxillomandibular fixation.

对67例下颌骨骨折患者的临床资料进行回顾总结，所有患者应用小型接骨板行坚固内固定治疗。其中7例颏部骨折，12例颏旁骨折，16例颏孔区骨折，9例体部多发性骨折，5例体部粉碎性骨折；18例合并其他部位骨折。所有患者术前经临床检查和影像学检查明确骨折的位置和骨折线的数目后，分段牙弓夹板结扎、颌间弹性牵引，使移位的骨折段逐渐复位；术中经口内切开复位、细钢丝颌间结扎、小型接骨板坚固内固定；术后行临床检查和影像学复查，必要时颌间弹性牵引7～10 d。结果所有患者手术切口ⅰ期愈合，治疗效果满意；临床检查所有患者牙合关系良好、面部对称；影像学复查证实骨折线对位良好。结论经口内切开小型接骨板坚固内固定辅以颌间固定治疗下颌骨骨折效果可靠，术后并发症少，是一种理想的手术方法。

Results All of the 58 caseshad tumefaction and pain. 45 cases were accompanied with shock, 30 cases with myoglobinuria, 15 cases with crush syndrome. In the group, 28 cases were operated for fasciotomy, 12 cases for amputation. 6 cases were treated with continous renal replacement therapy.

结果 本组所有58例患者均表现有局部肿胀、疼痛；有45例患者伴发休克，30例患者出现肌红蛋白尿，15例患者出现挤压综合征。28例患者行手术减压，12例行截肢手术，6例行持续性肾脏替代治疗。

Malignant plasmodium was founded in their blood samples.The epidemiological study showed,they had never gone to the higher malaria-epidemic areas in our country,such as Yunnan,Hainan,Guangxi,etc.During living overseas,they were all bitten by mosquito.Three cases were first infected,and others were recrudescence sufferers.When they came to hospital,the temperature was higher than 38.5℃.Except for the clinic symptom such as chill,fever,sweat etc.,five cases emerged tumid spleen and anaemia symptom.

结果〕温州口岸2005年1～7月共发现8例疟疾患者，均为国内人员国外感染，其中男性7例，女性1例，血液涂片均查到恶性疟原虫；流行病学个案调查结果显示，8例患者在国外期间均有蚊虫叮咬史；3例为初发病例，5例为复发病例；8例患者就诊时体温均超过38℃，并出现畏寒、发热、大汗等典型的疟疾临床症状，5例患者出现脾肿大和贫血症状，患者均无并发症状出现。

The two kinds of clefts are: unoperated isolate cleft palate and unilateral cleft lip and palate with lip only operated. Considering the effect of age on the results, The samples were divided into two age groups: mixed dentition stage and adult permanent dentition stage. The cases of these two groups of unoperated isolate cleft palate patients are 16 and 25 respectively, and those of unilateral cleft lip and palate with lip only operated are 15 all.

考虑到青春期生长发育对研究结果的影响，又分别将这两种类型的患者按年龄分成混合牙列期和成人恒牙列期两个年龄段，与相应年龄段的单纯腭裂术后患者、单侧完全性唇腭裂术后患者及非唇腭裂正常者进行比较，单纯腭裂未手术的患者混合牙列期和成人恒牙列期例数分别为16例和25例，单侧完全性唇腭裂仅修复唇裂患者混合牙列期和成人恒牙列期例数均为15例。

objectiveto investigate the efficacy and safety of amlodipine with berberine in the treatment of mild and moderate hypertensive with arthrolithiasis.methods 26 cases were treated by oral administration of amlodipine 5 mg, berberine 0.3g, meanwhile treated the acute arthrolithiasis by oral administration of colchicine 0.5mg, reated hypertensive with chronic gout by oral administration of allopurinol 100mg.

目的评价氨氯地平联用小檗碱治疗轻、中度老年高血压合并痛风患者的降压疗效。方法选择轻、中度老年高血压患者26例，给予患者口服氨氯地平5mg，1次/d，小檗碱0.3g，3次/d，同时给予急性痛风患者，口服秋水仙碱0.5mg，慢性痛风患者，口服别嘌呤醇100mg。

RESULTS: Of the 44 patients, 25 received adjuvant chemotherapy after operation; 1 received operation alone; 18 received induction chemotherapy. Of the 18 patients, 7 received tumor resection after chemotherapy; 2 patients with primary mediastinal chorioepithelioma with multiple metastases received radiotherapy on residual disease after chemotherapy; 1 patient with postoperative abdominal metastasis and 1 with postoperative lung metastasis achieved complete remission after chemotherapy; 1 patient with mediastinal sinus tumor achieved partial remission after chemotherapy; 6 had poor response to chemotherapy and died of disease progression.

结果：44例患者中，25例行术后辅助化疗；1例单纯手术；18例行诱导化疗，其中7例患者化疗后肿瘤缩小行手术切除，2例原发纵隔绒癌伴多发转移患者化疗后行残留病灶放疗，1例术后腹腔转移和1例术后肺转移患者化疗后获得完全缓解，1例原发纵隔内胚窦瘤化疗后部分缓解，未做进一步治疗，6例患者化疗无效进展死亡。

Methods We retrospectively studied clinical and EEC features of 80 patients with ICE. Ten patients were diagnosed with juvenile myoclonic epilepsy, 35 has absence epilepsy, 28 had generalized tonic clonic seizure, and 7 had adult-onset idiopathic generalized epilepsy.

回顾性分析80例特发性癫痫患者的临床和常规EEG特征。10例患者诊断为青少年肌痉挛癫痫，35例患者有失神发作，28例患者为全面强直痉挛发作，7例患者为成年期起病的特发性全面性癫痫。

Methods:a total of 50 patients of manic with agressive behavor and 50 patients with no agressive behavor were compaired with their rebation data.results: the two groups were signifcent different in brms and the dinical charaters.imply that the active,agression factor,dinical character of agressive history,irritably of brms were the agressive behavor danger factors.conclusions: to give nurse intervene and heath cducation in manic with agressive behavor early could decrease the agessive behavor mostly.

采用对照分析法，对50例有攻击行为的躁狂症患者和50例无攻击行为的躁狂症患者的相关资料进行分析和显著性检验。结果：两组躁狂症患者在brms和临床特征上存在显著差异，提示brms的动作活动、敌意因子分和临床特征中既往有攻击史，易激惹、不合作及医护人员的强制手段是躁狂症患者的攻击行为的危险因素。结论：及早对躁狂症攻击行为患者实施心理干预及健康指导，可以将攻击行为减少到最低限度。

objective to explore the reasonable utilization of cephalosporins in chronic renal failure patients with cephalosporin encephalopathy.method we retrospectively analyzed the clinical characteristics of 29 crf patients,who developed encephalopathic syndrome and was treated with cephalosporin.results the encepha1opathic syndrome include (1)mental confusion in 4 cases;(2)unconsciousness in 2 cases;(3)seizure in 23 cases.physical examination did not show signs of cerebral focal injury.computed tomography of the brain in 29 patients did not show acute lesions.the state of neurotoxicity was completely recovered after discontinuation of cephalosporins.conclusion cephalosporins used in conventional doses or reduced doses can cause temporary encephalopathy in patients with crfwhich might due to prolongation of drug half life.

目的 通过研究慢性肾功能衰竭患者抗生素脑病的发病机制和临床特点，探讨头孢菌素在crf患者中的合理应用。方法 29例crf患者在使用常规剂量或减量使用头孢菌素后出现神经精神症状，诊断为抗生素脑病，将其临床资料进行回顾性分析。结果神经精神症状表现多样：(1)精神异常4例，表现为胡言乱语、烦躁不安、睡眠倒错；(2)意识障碍2例，表现为嗜睡、昏睡、神志不清；(3)癫痫样抽搐23例，表现为肌阵挛、全身抽搐、癫痫样发作；部分患者同时出现几组症状。所有患者均无神经系统定位体征，行颅脑ct检查无急性病变。

Since historical times,England ,where the early inhabitants were Celts, has been conquered three times .

从有历史以来，英国，在此地早期居住的是凯尔特人，已经被征服了三次。

Bluetooth OBEX File Transfer Enables the sending and receiving of files on your phone via Bluetooth.

蓝牙OBEX文件移动允许经过蓝牙传送和接受文件。。。。