差分化

The staining intensity of CgA in different kinds of PNEC is related with the differentiation of tumor.

CgA在不同类型的肺神经内分泌癌的免疫反应强度与癌细胞的分化程度有关，分化好的癌较分化差的癌免疫反应强度高。

On the basis of the previous work, we make further study on the mechanism of the denucleation process, especially on the role of different cytoskeletal elements in the denucleation process. To clone and sequence a gene related to terminal differentiation of erythroblast, and construction of two cDNA libraries of erythroblast differentiation. The results of our study are as follows

本文在我室前期工作的基础上，对红系细胞终末分化中的排核机理作了进一步的探讨，克隆、测序并表达了一个与红系细胞终末分化相关的基因，另外，还成功地构建了小鼠终末分化和差减cDNA两个红系分化cDNA文库，为本室以后的基因克隆工作打下了基础。

The phenomenon of neuroendocrine differentiation exists in partial cases with thyroid papillary carcinoma, and the tissues of thyroid papillary carcinoma with neuroendocrine differentiation have poor differentiation and large tumor size.

部分甲状腺乳头状癌存在神经内分泌分化现象，伴神经内分泌分化的肿瘤组织分化较差？体积较大？

Proc Natl Acad Sci USA,1992,89:12160［4］Sneath R J,Mangham D C.The normal structure and funcion of CD44 and its role in neoplasia〔J〕.

该结果与胃和大肠癌CD44v蛋白表达不同，在胃癌组织中显示CD44v5，特别是在分化差的胃癌和转移性胃癌CD44v5比分化好的和非转移性胃癌的表达更强［7］。

The results above showed:(1) The cultivars of large-flowered chrysanthemum are widely distributed in Beijing area with plentiful floral types and floral colors;(2) The cultivars with the rare types and colors are urgent for protection;(3) Most of the quantitative characters obeys to the normal distribution,some important traits agreed with skewed distribution.The probability grading can assist quantitative character in establishing new grading standards;(4) Most of qualitative characters is asymmetrical in cultivars,which might be caused by unbalanced differentiation of characters or linkages coming from emphasis characters selection;(5) The floral characters are relatively stable and have comparably large influence on classification,the characters of stipule also have a certain degree of stability and can act as an reasonable supplement for cultivars classification,but the foliar characters have worse stability and can only be recognized as lower level criterion.(6) The genetic relationship among the Flat-petaled group,the Quilled-petal group and the Spoon-petaled group are closest,which followed by the Filiform-petal group because of long-term selection pressure for the specialization of the petal tip loved by most people.The Anemone-petal group has further genetic relationship with these four groups.(7) ISSR molecular marker detection indicates that the proportion of polymorphic loci of lardge-flowered chrysanthemum is higher,in which the Flat-petaled group has the highest genetic diversity level.

综合以上的研究结果表明：(1)北京地区现有大量大菊品种，且花型与花色较为丰富；(2)珍稀花型、花色品种亟需保护；(3)大部分数量性状是符合正态分布的，少数重点观赏性状迫于选择压力呈现偏态分布，概率分级法能够辅助大菊的数量性状建立新的分级标准；(4)大部分质量性状在品种群内的分布是不均匀的，可能是由菊花性状遗传分化的不均衡性或受到选育重点性状的连锁作用而造成的；(5)大菊花部性状相对稳定，对品种分类影响较大，其托叶部分也具有一定程度的稳定性，可以作为品种分类的合理补充，而叶部性状稳定性较差，在品种分类中应作为更次一级的分类依据；(6)平瓣类、管瓣类和匙瓣类的亲缘关系最近，畸瓣类品种花瓣先端特化受到人们的喜爱，长期的选择压力使其区别于3种基本瓣型，而这四种瓣型与桂瓣类在亲缘关系上较远；(7)ISSR分子标记检测表明：大菊品种多态性位点百分率较高，平瓣类品种的遗传分化最为丰富。

Incidence of micrometastasis in undifferentiated carcinoma was higher than that in differentiated carcinoma.

分化差的患者微转移发生率高于分化好的患者。

The incidence of micrometastasis in undifferentiated carcinoma was higher than that in differentiated carcinoma.

分化差的患者微转移发生率高于分化好的患者。

The percentage of TGF-β〓 positive cell in the pancreatic cancer tissue (43.8±5.2)％ was significantly higher than that in adjacent pancreatic tissue (28.7±3.6)％, P＜0.05. The worse the cancer cells differentiated and lymphy node metastasis, the more over-expression of TGF-β〓. 2. The percentage of Tr positive cell in the pancreatic cancer tissue (41±4)％ was significantly higher than that in adjacent pancreatic tissue (23±3)％, P＜0.05. The worse the cancer cells differentiated and lymphy node metastasis, the more over-expression of Tr, but the expression of Tr protein was not correlated with lymphy node metastasis (P＞0.05). 3. The percentage of β-GCD positive cell in the pancreatic cancer tissue (62.5± 4.1)％ was significantly higher than that in adjacent pancreatic tissue (33.5±2.8)％, P＜0.05. The worse the cancer cells differentiated and lymphy node metastasis, the more over-expression of β-GCD in pancreatic cancer tissue, but the expression of β-GCD protein was not correlated with lymphy node metastasis. P＞0.05. 4. the expression of β-GCD was significantly correlated with TGF-β〓 and Tr in the pancreatic cancer tissue.

结果如下：1、胰腺癌组织TGF-β〓阳性细胞百分率(43.8±5.2)％明显高于癌旁胰腺组织(28.7±3.6)％，P＜0.05；且癌细胞分化愈差或有淋巴结转移TGF-β〓过度表达愈多。2、胰腺癌组织Tr阳性细胞百分率(41±4)％，明显高于癌旁胰腺组织(23±3)％，P＜0.05；且不同分化程度胰腺癌组织Tr表达强度不同，分化程度愈低，表达强度愈高，P＜0.05；但胰腺癌Tr表达强度与淋巴结是否转移无关，P＞0.05.3、对于胰腺癌组织TGF-β〓和Tr表达，检测胰腺癌组织(32例)β-GCD阳性细胞百分率分别为(62.5±4.1)％或(62±4)％，分别明显高于癌旁胰腺组织β-GCD阳性细胞百分率(33.5±2.8)％或(43±3)％，P＜0.05；不同分化程度胰腺癌组织β-GCD表达强度不同，分化程度越低，表达强度越高，P＜0.05；但胰腺癌组织β-GCD表达强度与淋巴结是否转移无关，P＞0.05.4、TGF-β〓、Tr和β-GCD在胰腺癌组织中的表达随着分化程度的改变，呈现一致性的关系，而且TGF-β〓与淋巴结转移有关，Tr和β-GCD与淋巴结是否转移无关。

Results:The tumor was divided into two histologic subtypes:biphasic type(4 cases) and monophasic type(1 case).

结果 ：组织学检查分为双相性SRCC 4例，由癌和肉瘤样成分组成；单相性 1例，由差分化的肉瘤样梭形细胞、单核细胞与破骨细胞样多核巨细胞组成。

The differentiation ability of outward and middle bulb scale s was excelled inward ones.

3个品种外部鳞片和中部鳞片的分化能力大于内部鳞片；同一个鳞片上段鳞片的分化能力最差，下段最强；每块鳞片分化不定芽数也是上段最少，下段最多。

Objective To investigate the effects of interleukin-1 β converting enzyme gene on the biologic characteristics of ovarian cancer cells.

目的 探讨白细胞介素-1 β转换酶的表达，对卵巢癌细胞生物学特性的影响。

Campylobacter: This illness is the most commonly identified cause of diarrheal illness in the world.

弯曲：这种病是最常见的原因查明腹泻病，在世界上。