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Significant processing steps can include: a phase changes involving either the desired molecule or the solvent, inert carrier or vehicle, e.g., dissolution, crystallization, evaporation, sublimation, distillation or absorption; b a phase separation such as filtration or centrifugation; c any chemical change involving the desired molecule, e.g., removal or addition of water of hydration, acetylization, formation of the salt; d an adjustment of the solution containing the molecule such as adjustment of pH or pO2; e a precision measurement of contained or added BPC components, in-process solutions, recycled materials is performed, i.e., weighing, volumetric measuring, optical rotation, spectrophotometric determinations, etc.; and f changes occur in surface area, particle size, or lot uniformity, e.g., milling, agglomeration, blending.

意义较大的步骤可能会包括:a相变化,包括指定分子或溶剂,惰性载体或溶媒,如溶出作用,结晶,蒸发,升华,蒸馏或吸附;b相分离,如过滤或离心;c涉及指定分子的任一化学变化,如结晶水的除去或添加,乙酰化作用,成盐;d包含分子的溶解的调节,如调节pH或pO2;e 含有或添加原料药组分,过程内溶液,回收物料的精密测量,如,称重,体积测量,旋光度,分光光度测定,等和f 表面,粒度,或批一致性的变化,如磨碎,凝块,混合。

Clot lysis decreasedunder hypothermic and/or acidotic conditions, but increasedwith hyperthermia.

在低体温和/或酸中毒环境下凝块溶解减少,而在高体温下增加。

These depositsdecrease blood flow to the heart and may promote the formationof vessel-blocking clots, which can result in anginal chestpain or even a life-threatening heart attack.

这些储蓄减少血流对心脏,也许促进船阻拦的凝块的形成,可能导致anginal 胸口痛甚至一次威胁生命的心脏病发作。

Three years ago, Mary Chapin Carpenter suffered a life-threatening blood clot in her lungs.

三年前,玛丽蔡平卡彭特遭受了她的肺部危及生命的血液凝块。

Chymosin is extracted by washing and drying the stomach lining, which is then cut into small pieces and macerated in a solution of boric acid or brine at 30°C for 4-5 days.

凝乳酶是提取洗衣机和烘乾胃部内层,然后切成小块,并浸渍在解决硼酸或卤水在30 ℃为4-5天。

Methods A plasma clot clonal assay, immunocytochemical staining and Western blot were used in this study.

用血浆凝块巨核细胞集落培养,观察对生长的影响,并进一步使用免疫组化和Western blot证实受体的存在和对c-fos表达的影响。

After CPB, both CTand MCF were most improved with coadministration of rFVIIa andfibrinogen.

体外循环术后,在给予 rFVIIa 和纤维蛋白原后血凝块形成时间和血栓最大硬度均改善了。

They are activated by an array of stimuli including collagen and other factors in the subendothelial space exposed by disintegrity of vasculature architecture as well as by thrombin generated by the enzymatic coagulation cascades.

体循环携有止血所需的关键酶和细胞成分,同样循环中流经脉管系统的血小板是血凝块形成的中心环节。

The reason why only people with normal blood pressure should use the aspirin treatment is because, by interfering with the natural tendency of blood to clot, which gives it some protective effect against heart attack, at the same time aspirin increases the risk of haemorrhagic Stroke.

原因只有人民的正常血压应使用阿司匹林治疗是因为,干扰与自然趋势的血液凝块,这使一些保护作用对心脏病发作,在同一时间,阿司匹林增加的风险,出血性中风。

Note the dark red blood clot forming the hemopericardium.

注意暗红血凝块为心包积血,可致心包填塞。

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