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According to the spetial conformational analysis and physical/chemical property analysis and by the aid of computer it can make molecular design of mimic polypeptide and designs the polypeptide molecule with activity for neutralizing LPS, and adopts the solid phase polypeptide chemical synthesis method to synthesize antibacterial/antiendotoxin mimic peptide with total or partial BPI bio-function.

本发明公开了通过计算机模拟设计、人工合成的66个抗菌/抗内毒素模拟肽,根据对BPIN端三个LOOP区的空间构象分析及物理化学性质分析,在计算机辅助下进行模拟多肽的分子设计,设计出具有中和LPS活性的多肽分子,用固相多肽化学合成方法合成抗菌/抗内毒素模拟肽,本发明的抗菌/抗内毒素模拟肽具有全部或部分BPI的生物功能,可以用于治疗G-细菌感染、人内毒素血症,具有分子量小、可以稳定重复生产的特点。

But when they expressed alone, cry26 gene leaded inclusion body formation within or outside of the exosporium, whereas cry28 gene only induced crystal formation outside of exosporium. All of the proteins could not stably exist.

而当两个cry基因单独存在时,cry26基因表达合成的内含体位置不确定,大部分在芽胞外壁外侧形成,少数在芽胞外壁内侧形成;而cry28基因则只在芽胞外壁外侧表达合成内含体。

Then two star-shaped oligomers with designed molecular weights 5000 g mol-1 and 10000 g mol-1, respectively, were synthesized from D, L-lactide and glycolide as raw materials and pentaerythritol as initiator under catalysis of dibutyltin oxide.

合成的丙交酯和乙交酯为原料,季戊四醇为引发剂,氧化二丁基锡为催化剂合成出设计分子量为5000和10000两种预聚物。

As an intermediate for preparing vanillin derived from glyoxylic acid, 3, 4-dihydroxymandelic acid is synthesized based on condensation of catechol and glyoxylic acid in alkaline aqueous solution.

以邻苯二酚和乙醛酸为原料,在碱性条件下发生缩合反应,合成了3, 4-二羟基扁桃酸,此物质是多种香料和药物合成的重要中间体。

By adopting the method of stepwise synthesis, this paper synthetizes 1,3 - diaminopropanein 2-Hydroxy-3-methoxybenzaldehyde Zn-Sm heteronuclear bimetallic in Anhydrous methanol solution.

6楼本文采用分步合成的方法,在无水甲醇溶液中合成了1,3-丙二胺缩邻香兰素Zn-Sm异核双金属配合物。

By adopting the method of stepwise synthesis, this paper synthetizes 1,3 - diaminopropanein 2-Hydroxy-3-methoxybenzaldehyde Zn-Sm heteronuclear bimetallic in Anhydrous methanol solution.

本文采用分步合成的方法,在无水甲醇溶液中合成了1,3-丙二胺缩邻香兰素Zn-Sm异核双金属配合物。

To elucidate the structural features and the antimicrobial activity of this fragment, we re-designed and synthesized two peptides corresponding to the main mimic structures of Mytilin-1 from Mytilus coruscus, we named these two peptides Mytilin Derived Peptide-1 and Mytilin Derived Peptide-2, respectively.

为验证该区域是否具有抗菌活性,通过对厚壳贻贝Mytilus coruscus抗菌肽Mytilin进行空间结构模拟,选取其中β-发夹部分肽段,采用了固相化学合成的方法合成了两条10肽,分别命名为Mytilin Derived Peptide-1 (MDP-1)和 Mytilin Derived Peptide-2 (MDP-2)。

Layered double hydroxides pillaring with organic anion s CoAl-LDH are directly synthesized by a homogeneous precipitation method using the urea as a precipitiant,and the LDH products have been characterized through XRD,FT-IR,TGA and TEM.

以尿素为沉淀剂用均匀沉淀法直接合成有机阴离子柱撑水滑石(LayeredDoubleHydroxides,LDH)及CoAl水滑石等,并用XRD,FT-IR,TGA,TEM等分析手段对所合成的水滑石进行了表征。

The content of intermediates such as protochlorophyll,Mg protoporphyrinand protoporphyrin IXwere reduced and δ aminolevulinc acid and porphohilinogenwere markedly accumulated in albino seedlings of W1,which proved that there was a blockage in the formation of uroporphyrinogen or coproporphyrinogen during Chl biosynthesis under lower temperature.

白化苗中Chl生物合成的中间产物原叶绿素、镁原卟啉、原卟啉IX含量减少,而δ氨基酮戊酸和胆色素原大量积累,证明突变体W1低温下Chl生物合成卟啉原形成部位受阻

Magnesium trisilicate was synthesized by precipitation using Na2OnSiO2 and Mg (NO3)2 as raw materials.

由Na2OnSiO2和Mg(NO3)2经沉淀法合成了三硅酸镁,用450℃煅烧或酸化方法对合成的样品进行改性。

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