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Method]twenty six wistar rats were divided into two groups, with 13 in each group, peroneal nerve was transacted on the right side of all the animals, in one group, the proximal end of peroneal nerve was turned back and ligated, the distal end was sutured to the side of tibial nerve with perineurial window, in another group,both ends of the transacted peroneal nerve were turned back and ligated as contrast, no operation was done on the left side.

方法]wistar大白鼠26只,随机分实验组和对照组,每组13只,实验组右侧腓总神经切断后,近端反转结扎,远端与胫神经外膜开窗处行端侧吻合,对照组右侧腓总神经切断后,两端均反转结扎,两组动物左侧作正常对照,不作处理。术后3个月,行双侧腓总神经、胫前肌组织学检查,胫前肌湿重测定,运动终板检查。

RESULTS: Compared with patients in the non-AD group, those in the AD group showed decreased cerebral glucose metabolism mainly in the temporal and frontal lobes and the limbic system in the right cerebral hemisphere and the inferior frontal gyrus and precentral gyrus in the left cerebral hemisphere, and increased cerebral glucose metabolism mainly in the temporal and occipital lobes in the right cerebral hemisphere and the parietal and occipital lobes and limbic system in the left cerebral hemisphere.

结果: 抑郁焦虑组与非抑郁焦虑组比较,脑葡萄糖代谢下降的脑区集中于右侧大脑半球,主要位于颞叶、额叶及边缘系统,左侧大脑半球较少,主要位于额下回和中央前回;脑葡萄糖代谢升高的脑区集中于右侧大脑半球的颞叶、枕叶和左侧大脑半球的顶叶,枕叶及边缘系统。

3D MDD patients showed significantly lower gray matter density than controls in right medial frontal gyrus, right temporal pole, bilateral putamen and globus pallidus, bilateral cerebellum. After treatment, gray matter density in right superior frontal gyrus, bilateral precentral gyrus, temporal pole, putamen and globus pallidus, and cerebellum in patients were still significantly lower than controls.

发作期抑郁症患者右侧额内侧回和同侧颞极、双侧壳核/苍白球和双侧小脑的灰质密度较正常人低;治疗后右侧额上回、双侧中央前回、双侧颞极、双侧壳核/苍白球和双侧小脑的灰质密度仍较正常人低。

Two months after a reading invention program based on auditory training, the dyslexic children received another imaging scan using the same tasks. The results showed that the bilateral brain activation of the dyslexic children was significantly higher than the pre-training, especially in the cingulate gyrus (BA23) of bilateral frontal lobe, the bilateral supramarginal gyrus (BA40), the left precuneus (BA7), the right temporal-parietal region (BA22 and BA48) and the right middle frontal gyrus(BA8), suggesting that the activation pattern of the dyslexia for phonological processing gradually changed to that of the normal ones.

阅读困难儿童接受基于听觉和语音的阅读干预训练程序两个月后,再次进行同样任务的脑成像扫描发现,阅读困难儿童双侧脑区的激活都显著高于训练前,尤其是在双侧额叶中扣带回(BA23)、双侧缘上回(BA40)、左侧楔前叶(BA7)、右侧颞顶(BA22和BA48)、右侧额中回(BA8)的活动增强,表现出语音加工过程中大脑功能活动模式逐渐趋向阅读正常儿童的大脑功能模式。

Result: Compared to normal subjects, some functional regions associated with encoding, maintenance and retrieval process showed increased activation in schizophrenia patients, i.e. right precuneus for encoding process, left PMA, left DLPFC, right precuneus and left VLPFC for maintaince process, left PMA for retrieval process. In addition, subcortical structures, primary motor cortex and some verbal regions in left temporal lobe also showed more activation.

结果:与正常组比较,患者组工作记忆不同认知过程的执行脑区激活程度增加,编码期激活增加脑区为右侧楔前叶,维持期激活增加脑区为左侧PMA、左侧DLPFC、右侧楔前叶及左侧VLPFC,提取期激活增加脑区为左侧PMA,而且患者组还激活了更多皮层下结构、初级运动皮层及左侧颞叶语言相关脑区。

No significant correlation was found between rCBF in different brain regions and psychopathologic symptoms and efficacy as well.

结果提示精神分裂病人存在右侧额叶与右侧颞叶局部脑功能减退,但未发现局部脑血流与精神病理症状和疗效有关

During encoding, the right amygdala and right pulvinar were activated when subjects unconsciously encoded fearful faces (vs. neutral faces).

在编码阶段,与中性面孔相比,恐惧面孔在无意识编码的被试中激活了右侧杏仁核和右侧枕核;而在有意识编码的被试中激活了左侧杏仁核。

During open/close movement, the distance of condylar movement is smaller than normal occlusion(P.05). During protrusion/retrusion movement, protrusion extent increase,the distance of condylar movement is bigger than normal occlusion(P.05). During lateral excursion, the trace in sagittal plane of the non-working side condyle is more incline than protrusion movement trace and the distance of the left non-working side condylar movement is larger than the right. During mediotrusion/right movement, the left biggest space distance is larger than normal occlusion and the transversal condylar inclination is smallar than normal occlusion when the distance of condylar movement is 5mm, the difference is statistically significant.

在开闭口运动时,双侧髁突运动幅度减小、位移量小于正常牙合者(P.05);前伸后退运动时,前伸幅度增加,位移量大于正常牙合者(P.05);侧方运动时,非工作侧髁突在矢状面上的轨迹较前伸轨迹向前下方倾斜度增加,非工作侧髁突空间位移左侧大于右侧,向右侧方运动中,左侧髁突空间位移大于正常牙合者,髁突位移5mm时水平面髁突倾斜度小于正常牙合者,差异有统计学意义。

When the parameter matching of the wheel location is improper, namely, the matching between the wheel toe-in and the wheel camber angle is ill-suited, abrasion of the two wheels of the same steering axle is inside or outside simultaneously, because of wheels sideslip. However, when double-front-axle steering system failure take place, abrasion of the two wheels of the same steering axle is in the same side, and that, tyre abrasion direction of front and back steering axles is rightabout. That is to say, if tyre abrasion of front steering axle lie in the left side, tyre abrasion of back steering axle lie in the right side to a certainty, which is the rule of tyre abrasion of double-front-axle steering automobile.

当定位参数匹配不当时,同一转向轴上左右车轮的磨损部位都在内侧或外侧,原因是左右车轮在滚动的同时还要产生相向或反向侧滑;而双前轴转向汽车前、后转向轴引导汽车转向方向不一致时,同一转向轴左、右车轮的磨损部位都在同一侧,而且前、后转向轴上的车轮偏磨损方向正好相反,即如果前转向轴左、右车轮磨损部位在左侧或右侧,那么后转向轴左、右车轮磨损部位就在右侧或左侧,这是双前轴转向汽车特有的轮胎磨损规律。

There were no significant differences for the firing rates in the site of contralateral TNC neurons among during pre-CSD,CSD,and post-CSD (P>0.05).For flunarizine group,the firing rates in the site of ipsilateral TNC neurons during pre-CSD were higher as compared with during CSD(P<0.05).2.1 There were statistical differences on palasma levels of CGRP and SP among the three groups(P<0.05).The levels of CGRP and SP in CSD group were higher than control group(P<0.05).No significant differences on the levels of CGRP and SP in ipsilateral trigeminal ganglia were found among the three groups(P>0.05).2 The number of neurons with positive CGRP and SP immunoreactivity was statistically different in right-sided trigeminal ganglia among the three groups (P<0.05).The number in fight-sided trigeminal ganglia in CSD group was higher as compared with control group(P<0.05).The number in right-sided trigeminal ganglia was statistically higher than that in left-sided trigeminal ganglion in CSD group(P<0.05).3.1 Altered ReHo in ipsilateral pons and other brain regions response to pain such as basal nuclei,thalamus,cingulated gyms and prefrontal cortex was detected during the acute spontaneous attack as compared with during headache remission(P<0.05,corrected by Monte Carlo simulation). 2 Positive functional connectivity was detected between ipsilateral pons and other brain regions related to pain within pain state and within non-pain state (P<0.05,corrected by false discovery rate,FDR).Increased functional correlation between ipsilateral pons and other pain-related brain regions such as ipsilateral prefrontal cortex and contralateral subcallosal gyrus was detected during the acute spontaneous attack as compared with during headache remission(P<0.05,corrected by Monte Carlo simulation).

结果1。对照组未发现CSD;同侧TNC放电频率,CSD中>CSD后>CSD前P<0.05对侧TNC放电频率,CSD前、中、后无统计学差异(P>0.05氟桂利嗪组同侧TNC放电频率,CSD前>CSD中(P<0.05),CSD前与CSD后及CSD中与CSD后之间无统计学差异(P>0.05)。2.1关于放免测定,各组血浆CGRP、SP水平有统计学差异(P<0.05),CSD组高于对照组(P<0.05),CSD组与氟桂利嗪组、对照组与氟桂利嗪组之间均无统计学差异P>0.05各组之间同侧三叉神经节中CGRP、SP水平未见变化(P>0.05.2关于免疫组化研究,右侧三叉神经节CGRP、SP免疫阳性细胞数三组之间有统计学差异(P<0.05),多重两两比较结果CSD组大于对照组(P<0.05),CSD组与氟桂利嗪组之间、对照组与氟桂利嗪组之间无统计学差异P>0.05左侧三叉神经节CGRP、SP免疫阳性细胞数三组之间无统计学差异(P>0.05CSD组中右侧三叉神经节CGRP、SP免疫反应阳性细胞数大于左侧(P<0.05)。3.1局部一致性分析发现两组患者头痛疼痛状态较非疼痛状态脑活动发生变化的脑区有同侧脑桥以及其他疼痛相关脑区如基底节区、丘脑、扣带回、前额叶皮层等(P<0.05,蒙特卡罗模拟校正)。2功能连接分析发现疼痛状态与非疼痛状态下主要疼痛相关脑区均与同侧脑桥有功能联系P<0.05,false discovery rate,FDR校正疼痛状态与非疼痛状态比较,同侧前额叶皮层、对侧胼胝下回等疼痛相关脑区与同侧脑桥之间功能联系增强(P<0.05,蒙特卡罗模拟校正。

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