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Importantly, T cells engineered to express a rapamycin-resistant mTOR construct are resistant to anergy induction caused by rapamycin.

重要地是,T细胞表达人为构造的耐受雷帕霉素mTOR可对抗雷帕霉素诱导的无能。

Can be used for types that are neither Assignable nor Copy Constructible.

可用于既不可赋值也不可复制构造的类型。

The developed algorithm in this paper is not only applied to theoptimization of multilayer antireflection coatings,but also the automaticdesign of filter and beam splitter with complex coating system.

本文构造的多层光学薄膜遗传算法不但能够设计多层增透薄膜和复杂的分光镜,而且还可优化设计滤光片。

The thesis studies the difference between GWSs composition and traditional workflow applications, proposes the implement mechanism and technical architecture of GWSs composition and defines the reference model of GWSs composition platform, which provide holistic framework and top-level guidance for studying dynamic GWSs composition technology, designing GWSs composition platform, and implementing representative composite service applications.2、Theories and methods of composite process modeling and process analysis. This thesis proposes a meta-model of Geo-spatial Web services composition process defining from two aspects, i.e. process and resource. According to the process definition meta-model, we propose a new Geo-spatial Web services composition Process/Resource model based on extended WF-net, which effectively resolves the problems on uncertain activity option and dynamic variation of service in composite process model. A notion with regard to soundness of process model is proposed from three aspects, i.e. the structural correctness of process model, validity of data link and validity of resource. The notion of soundness definitely gives a dividing line on correctness of composite GWS process. This thesis analyzes sufficient and essential terms of soundness, and studies compositional property of WSCP/R-net models which provides an effective method to construct a soundness WSCP/R-net model. According to WSCP/R-net, the thesis proposes composition algebra and studies the properties of it. Based on the composition algebra, 6 kinds of composite process reduction rules are induced to optimize the process.3、Geo-spatial Web service QoS model and its application architecture. This thesis proposes an extendable GWS QoS model from three aspects, i.e. Geo-spatial Web Service itself, networking conditions and service consumer which can be used to distinguish GWSs with overlapping or identical functionality. We work over the QoS evaluation methods of composite GWS process which can be used to guide the execution, monitor and service selection of composition process. Aming at some disadvantages in traditional Web service discovery model for its lacking of QoS supporting, this thesis proposes a new service discovery model SDMQ supporting QoS constraints.4、Technologies of composite service executing. SSPL, a new composite service process language, is defined to overcome the disadvantages of existing composite services process languages which can not adapt to the dynamic variation of Geo-spatial Web Services. An algorithm is described to translate WSCP/R-net model into SSPL. The thesis studies the model of dynamic services selection with QoS global optimization, presenting an algorithm GODSS to resolve dynamic services selection with QoS global optimization in GWSs Composition.5、Design and implement experimental system and representative applications. According to the research findings presented above, we design and implement an experimental system and construct two representative applications to show that our achievements are effective and practical.

针对当前空间信息服务聚合研究中存在的若干不足,本文重点在基于工作流的空间信息服务聚合框架、空间信息服务聚合流程建模和分析技术、空间信息服务QoS模型及应用体系以及空间信息服务聚合流程执行等几个方面进行深入研究,主要工作和创新点包括:1、基于工作流的空间信息服务动态聚合框架:研究了空间信息服务动态聚合和传统工作流应用的不同,在此基础上提出了基于工作流技术的空间信息服务动态聚合实现机制、技术体系和参考模型,为研究空间信息服务聚合的关键技术、开发服务聚合支撑平台以及在此基础上构造特定的空间信息服务聚合应用提供了总体框架和顶层指导。2、空间信息服务聚合流程建模和分析技术:首先基于动态服务聚合流程建模的需求和空间信息服务动态变化的应用实际,从服务聚合的过程维和资源维出发定义了服务聚合流程定义元模型;与之相对应,对基本的WF-net进行扩展,提出服务聚合流程/资源网作为空间信息服务聚合流程的形式化描述模型,有效解决了现有的基于基本Petri网和工作流网的服务聚合建模方法所不能解决的不确定路径选择和服务的动态变化性问题;从流程结构正确性、数据依赖有效性和资源实现有效性三个方面提出了WSCP/R-net健壮性的概念,明确界定了聚合流程正确性的标准,并对WSCP/R-net模型的健壮性分析方法和WSCP/R-net模型的组合特性进行了研究;提出了空间信息服务聚合代数算子并对其性质进行了研究,在此基础上提出了6种聚合流程约简规则,从而可达到优化聚合流程、提高聚合流程执行效率的目的。3、空间信息服务QoS模型和应用体系:从服务本身、网络环境和服务消费者三个层次出发,提出了一个可扩展的空间信息服务QoS模型GSQM,实现了对空间信息服务的度量和评价,并对GSQM不同质量要素信息的客观、公正采集方法进行了研究;研究了空间信息服务聚合流程QoS评价方法,有效支持了空间信息服务聚合流程的执行、监控以及服务选择等操作;针对目前的服务发现模型仅支持服务功能性描述、不能有效满足空间信息服务应用需求的现状,提出了一种新的支持QoS约束的服务发现模型SDMQ,并对模型的实现框架进行了研究。4、空间信息服务聚合流程执行技术:针对现有的服务聚合流程描述语言不能有效满足空间信息服务动态聚合流程描述的特点,基于BPEL4WS提出了一种新的空间信息服务聚合流程描述语言SSPL;研究了满足健壮性要求的WSCP/R-net模型向SSPL的转换算法,在此基础上可以满足用户无显式编码来实现空间信息服务聚合应用的目的;研究了服务动态选择QoS全局优化模型,并在此基础上提出了一种解决服务动态选择QoS全局优化问题的实现算法GODSS.5、基于论文研究成果,设计实现了"空间信息服务聚合实验系统",并构建了"矿产资源评价"和"城市消防应急响应"两个典型应用案例,对论文所述模型、方法的可行性和有效性进行了验证。

Based upon all above-mentioned, a mathematical representation for multi-material structures is proposed by means of vector level sets, and the general structure topology optimization can be expressed by a constrained functional minimization problem of a set of level set functions.

同时,还提出了在有效约束切空间上构造的非线性映射技术,以改进向量水平集的演化方向,可提高计算效率2到3倍。

Value_type is move constructible.

value_type 是可移动构造的。

The mass conservative interpolation function is based on the stream function.

根据流函数可构造质量守恒的插值函数。

Exive least-squares solutions, antire?exive least-squares solutions, bisymmetric least-squaressolutions, symmetric and antipersymmetric least-squares solutions, symmetric or-thogonal symmetric least-squares solutions, symmetric orthogonal antisymmetricleast-squares solutions and their optimal approximation to the linear matrix equa-tion AX = B, and solve them successfully. 2. For Problem II, we can convert it to another problem of finding the least-squares solutions with the least norm of a new consistent matrix equation. Onthe base of the solutions of Problem I we can apply the iterative method to get

本文所构造的迭代法的优点在于先利用法方程变换将求矩阵方程的最小二乘解转化为求一个相容矩阵方程的解的问题,再利用迭代法对于任意给定的初始矩阵进行迭代,均可在有限步内迭代出所求问题的一个解;可将问题II转化为求新方程的极小范数解的问题,同样用迭代法求解,从而系统且全面地解决了问题I、II在约束矩阵类如中心对称、中心反对称、自反矩阵、反自反矩阵、双对称、对称次反对称、对称正交对称、对称正交反对称矩阵中的最小二乘解及其最佳逼近问题。

The system may be configured as either a single-stage mode wherein the first gearset assembly (42) is received in the gearbox (40) to produce a rotational speed adjustment between the shafts, or a multi-stage mode wherein both the first and second gearset assemblies (42,44) are received in the gearbox (40) and are connected in series to produce a different rotational speed adjustment.

本系统可构造成单级模式或者多级模式,在该单级模式下第一齿轮组组件容纳在齿轮箱内以便在所述轴之间产生转速调节,在该多级模式下第一和第二齿轮组组件都容纳在齿轮箱内并串联连接以便产生不同的转速调节。

The traditional plate tectonic theory considers plate as a rigid body, but really plate is deformable.

摘 要 传统板块构造理论认为板块是一个刚体,实际上板块是可变形的。

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Since historical times,England ,where the early inhabitants were Celts, has been conquered three times .

从有历史以来,英国,在此地早期居住的是凯尔特人,已经被征服了三次。

Bluetooth OBEX File Transfer Enables the sending and receiving of files on your phone via Bluetooth.

蓝牙OBEX文件移动允许经过蓝牙传送和接受文件。。。。

The almost sure central limit theorem is a pop topic of the probability research in recent years,because it has many actual applications in the random analogue.

中文摘要:几乎处处中心极限定理是近几十年概率论研究的一个热门话题。它之所以引起人们的注意是由于它在随机模拟方面的实际应用参见Fisher