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The completely diagonalized Hamiltonian matrices of 3d2/3d8 ion configuration in the trigonal symmetry have been established by irreducible representation method. Taken into account the influence of the spin-spin coupling interactions omitted in previous publications, the spectra and the constants of crystal structure and zero-field splitting parameters of CsNiCl3 crystal and CsNiCl3: Mg2+ crystal are calculated and the influence of the doping to the spectra, the constants of crystal structure, zero-field splitting parameters and Jahn-Teller effect are studied. The results show that doping can change the structure of crystal which brings about the changes in the spectra and zero-field splitting parameters as well as Jahn-Teller effect.

应用不可约张量理论构造了三角对称晶场中3d2/3d8态离子的45阶可完全对角化的微扰哈密顿矩阵,在考虑了以前工作中被忽略的自旋-自旋耦合作用的基础上计算了CsNiCl3晶体和CsNiCl3:Mg2+晶体的基态能级、晶体结构、零场分裂参量和Jahn-Teller效应,研究了掺入Mg2+对CsNiCl3晶体的光谱、零场分裂参量及Jahn-Teller效应的影响和自旋单重态对基态能级的贡献,发现掺杂使得晶体结构产生畸变,从而改变晶体光谱的精细结构和零场分裂参量,不改变Jahn-Teller效应的分裂规律但改变分裂的大小。

Retroreflector array is used as pseudo phase conjugator in the system. The fidelity of the conjugate wave and matching problem of the retroreflector array and Hartmann-Shack wavefront sensor is discussed. Several data fusion methods are presented in order to having two Hartmann-Shack wavefront sensors control one set of wavefront corrector. The misalignment errors of Hartmann-Shack wavefront sensor and arrangement errors of wavefront sensor and deformable mirror are analyzed. At the same time, numerical work based on the data of practically system, such as 61 element AO system, are done corresponding to the problem respectively and the results are given.The system of CP/CM AO is setup to fulfill all the functions.

针对不同的应用环境,提出了四种CP/CM衍生光路;进行了关键器件——角反射器阵列的保真度分析,给出了角反射器阵列作为伪相位共轭器件,与哈特曼—夏克波前传感器的匹配条件,认为角反射器阵列的布局要与哈特曼波前传感器的微透镜阵列布局完全对应,才能达到最优探测效果;提出了四种双哈特曼传感器控制一套波前校正器的数据融合方式,并逐一进行了分析,认为加修正因子斜率融合和电压融合方式在目前工程中是适用的,并进行了相应的数值模拟;给出了哈特曼传感器自身的调整误差分析过程,得到了误差可通过常规标定消除的判断依据;通过数值计算,得到了常规自适应光学系统和CP/CM系统哈特曼传感器和变形镜的对准误差对系统性能的影响,给出了两种系统对于不同对准误差情况下校正效果的变化情况和相应系统容限;以37单元自适应光学系统为基础,搭建了CP/CM自适应光学系统光路,并完成了系列CP/CM功能实现实验,运用双哈特曼传感器数据融合,成功实现了CP/CM自适应光学系统的闭环实验。

Retroreflector array is used as pseudo phase conjugator in the system. The fidelity of the conjugate wave and matching problem of the retroreflector array and Hartmann-Shack wavefront sensor is discussed. Several data fusion methods are presented in order to having two Hartmann-Shack wavefront sensors control one set of wavefront corrector. The misalignment errors of Hartmann-Shack wavefront sensor and arrangement errors of wavefront sensor and deformable mirror are analyzed. At the same time, numerical work based on the data of practically system, such as 61 element AO system, are done corresponding to the problem respectively and the results are given. The system of CP/CM AO is setup to fulfill all the functions. Through the data fusion of two Hartmann-Shack wavefront sensors, the system runs successfully and realizes the close loop. It lays a good foundation for the application of CP/CM AO. Another aspect of this paper is to expand the working band of Hartmann-Shack wavefront sensor through Frequency Transfer of Nonlinear Optics.

针对不同的应用环境,提出了四种CP/CM衍生光路;进行了关键器件——角反射器阵列的保真度分析,给出了角反射器阵列作为伪相位共轭器件,与哈特曼—夏克波前传感器的匹配条件,认为角反射器阵列的布局要与哈特曼波前传感器的微透镜阵列布局完全对应,才能达到最优探测效果;提出了四种双哈特曼传感器控制一套波前校正器的数据融合方式,并逐一进行了分析,认为加修正因子斜率融合和电压融合方式在目前工程中是适用的,并进行了相应的数值模拟;给出了哈特曼传感器自身的调整误差分析过程,得到了误差可通过常规标定消除的判断依据;通过数值计算,得到了常规自适应光学系统和CP/CM系统哈特曼传感器和变形镜的对准误差对系统性能的影响,给出了两种系统对于不同对准误差情况下校正效果的变化情况和相应系统容限;以37单元自适应光学系统为基础,搭建了CP/CM自适应光学系统光路,并完成了系列CP/CM功能实现实验,运用双哈特曼传感器数据融合,成功实现了CP/CM自适应光学系统的闭环实验。

The growth inhibiting rate of T24 cell lines were detected by MTT methods, apoptosis of cells were detected by flow cytometry, the mechanism of apoptosis was analyzed by detecting the protein expression of Bcl-2, Bax, Caspase-9, Caspase-3 and cytoplastic protein Cytochrome C. 4 We injected live T24 cells into the subcutaneous space of nude mice and successfully built up the animal model of bladder carcinoma. The effect of CS-PAA-EPI polymer magnetic microspheres targeting chemotherapy was investigated by HE staining, TUNEL ,tumor weight and volume inhibition rate. Results: 1 TEM revealed that the CS-PAA polymer magnetic microspheres were regular spherical shape,the average diameter was 80nm in dry condition. By controlling the pH value of the medium,polymers had positive or negative zeta potential. VSM showed the CS-PAA polymer magnetic microspheres had superparamagnetic. The diameter of CS-PAA-EPI polymer magnetic microspheres were 200nm in solution by DLS examining,the embedding ratio was 20%,the EPI loading rate was 15%, which was higer than reported in other articles. 2 Raw eye observation found that the rat"s bladder of treatment group was brown color,which meaned the aggregation of iron particles, compared with the control group, iron stain found iron particles were assembled in rat"s bladder of the treatment group, the amount of iron particles in liver and spleen were less obviously.

研究结果:1合成的CS-PAA磁性聚合物微球呈球形,大小均一,TEM测定其干态下粒径为80nm左右,磁化曲线证实具有超顺磁性,具有一定的PH敏感性,固载表柔比星后,水溶液性状稳定,无沉淀物,DLS测定直径约200nm左右,测定载药率为15%,较文献报道高,包封率为20%。2肉眼观察试验组大鼠膀胱表面呈褐色,可见大量的Fe粒子聚集,普鲁士兰染色法显示,试验组大鼠膀胱壁内有大量的Fe粒子,分布至膀胱壁全层,与对照组大鼠相比,试验组大鼠的肝、脾内的Fe粒子聚集量明显降低;HPLC测定结果与Fe染色相同;高剂量磁性CS-PAA-EPI生理盐水组及单纯EPI生理盐水组均在给药后14天出现血肌酐和尿素氮的升高,其他组大鼠血生化指标没有明显变化。3MTT法发现,高、中、低剂量磁性CS-PAA-EPI生理盐水组在外加磁场的协同作用下杀伤T24细胞效应明显高于单纯的EPI生理盐水组,FCM发现试验药物组可引起明显的肿瘤细胞凋亡,试验药物治疗组细胞胞浆内出现了由线粒体释放出的细胞色素C,试验组细胞Bcl-2蛋白减少,Bax蛋白变化不明显,Caspase-3、Caspase-9蛋白受到了激活活化。4高、中、低剂量磁性CS-PAA-EPI生理盐水组的瘤重抑制率和瘤体积抑制率均明显高于单纯的EPI生理盐水组(P<0.01),其中高剂量组的抑制率最高。

The composition comprises: 35 to 65 wt % of an anionic detergent or surfactant selected from alkyl benzene sulphonic acids, alpha olefine sulfonates, long chain fatty acid sulphates, higher fatty acids, as well as the alkali metal and alkaline earth metal salts thereof, and natural detersive agents, and mixtures of any of these; 3 to 15 wt % of a non-ionic detergent or surfactant selected from alkoxylated alkyl phenols and alkoxylated fatty alcohols; 5 to 10 wt % of a water-swellable cellulose derivative or a salt thereof, wherein the cellulose derivative exhibits a viscosity of at least about 1500 cps, measured in a 1 % aqueous solution at 25 DEG C with a Brookfield viscometer having spindle 3, speed 30rpm, factor 40 for viscosities of 2500-3500 cps; 6 to 20 wt % of a solubility regulator selected from alkali metal and alkaline earth metal chlorides, carbonates and sulphates, aluminosilicates and starch; and 0 to 20 wt % of a fragrance or perfume in solid, liquid or microencapsulated form.

该组合物包含:a35―65%重量的阴离子洗涤剂,其选自烷基苯磺酸、α-链烯烃磺酸盐、长链脂肪酸硫酸盐、高级脂肪酸以及其碱金属和碱土金属盐和天然的去污剂,和任何这些组分的混合物;b)3―15%重量的非离子洗涤剂,选自烷氧基化烷基酚和烷氧基化脂肪醇;c)5~10%重量的水可溶涨的纤维素衍生物或它们的盐,其中纤维素衍生物按1%水溶液在25℃下用Brookfield粘度计(3号转轴,转速30rpm,2500―3500cps粘度的因子是40测定;具有粘度至少约1500cps;d)6―20%重量的溶解性调节剂,选自碱金属和碱土金属氯化物、碳酸盐和硫酸盐、硅铝酸盐和淀粉;和e)0~20%重量的为固体、液体或微囊包封形式的香精。

According to the above study result, the diversity of microorganisms population in the SUFR system is complex and the bio-community formed in the SUFR system is stable. The close relations between abundance of bacteria and nutrients were found. The correlation between heterotrophic bacteria and COD was 0.949. The correlation between organic phosphate bacteria and TP was 0.815. The correlation between nitrosobacteria and NH3-N was 0.909. The correlation between disnitrifier bacteria and TN was 0.653. These inneglectable great factors effecting on phosphorus-uptake and phosphorus-release of phosphorus accumulating organisms are the influent COD、the concentration of DO、the sludge retention time、the temperature. The diversity of organic phosphate bacteria population in the SUFR reactor was complex and there is no phosphate bacteria taking the absolute superiority in quantity. The near-native pure culture method powerfully complement the traditional pure culture technique and enrich culture technique. The sludgy bioactivity is very good in whole SUFR reactor. By the quality of being biochemistry, the anaerobic phase is higher than anoxic phase and the anoxic phase is higher than aerobic phase of SUFR.

通过以上试验内容研究发现,SUFR 系统中的微型动物种群较多,微生物生态系统稳定;系统中微生物的数量与营养盐的含量密切相关,其中总异养菌与COD的相关系数r 为0.949,有机磷细菌与TP 的相关系数r 为0.815,亚硝化菌与NH4+-N的相关系数r 为0.909,反硝化菌的数量和TN 的相关系数r 为0.653;污水生物除磷工艺中进水COD 的浓度、DO 浓度、泥龄的长短、温度都是影响聚磷菌释磷及吸磷效果的不可忽视的因素;SUFR 系统中的磷细菌呈现种群多样化的趋势,没有占绝对优势数量的磷细菌;微孔滤膜近自然培养法是对传统纯培养技术和富集培养技术的有力补充;整个SUFR 反应器系统中污泥的生物活性很好,就可生化性来讲,厌氧反应器大于缺氧反应器大于好氧反应器;按照动力学方程式求出的细胞生长动力学特征值和SUFR 脱氮除磷系统工艺的实测值结果基本吻合。

Also, by using a novel offset architecture, as opposed to completely overlapped architecture, for the differential transmission pair, a 33% reduction of thickness is achieved in the design of a miniaturized common-mode filter with multi-layer LTCC technology. In view of increasing need of high-speed clock and data circuits to control their skew problems, a design of LTCC delay line is then conducted. To improve the waveform distortion associated with the microstrip/stripline-type meander delay line, a miniaturized high-frequency 3-D delay line with grounded guard traces is introduced. By means of 3-D structure, the 233 ps delay time, which requires extra board space amounting to a factor of 2.34 by stripline type meander delay line, can be shrunk into an EIA 1206 form factor.

为因应高速时脉及高速线路的不断发展,用於控制讯号、时脉同步的延迟线路需求日益增加,接著讨论的题目便是应用低温共烧陶瓷制程技术设计多层的延迟线路元件,为了改善在微带线/带线型折线式延迟线路波形失真的问题,论文中提出以接地的防护线来设计小型化的三维多层延迟线路元件,比较应用带线型折线式延迟线路和应用三维架构设计的延迟线路元件,同样提供233 ps的延迟时间,多层架构设计之延迟线路可缩小至EIA 1206 的尺寸,省下2.34倍的电路板面积。

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