卵黄囊

We creatively used yolk sac membrane to assess the antiangiogenic activity of rhK1-3 in vivo.

创造性地建立了鸡胚卵黄囊膜(yolk sac membrane， YSM)血管生成模型，在器官水平上研究了rhK1-3对鸡胚YSM血管生成的影响。

The indistinguishable yolk sac tumors cell in teratomas can be found by AFP staining combined with SP1 staining.

AFP和SP1可检出畸胎瘤中不易察觉的卵黄囊癌成分。

The first passage of YS-MSCs which grew in good condition was obtained, and adipogenic differentiation of YS-MSCs was induced by dexamethasone and insulin, and angioblast was induced by vascular endothelial growth factor and basic fibroblast growth factor.

取生长状态良好的第1代细胞，以地塞米松、胰岛素定向诱导卵黄囊间充质干细胞向脂肪细胞方向分化；以血管内皮生长因子和碱性成纤维细胞生长因子体外诱导其向血管内皮细胞方向分化。

BACKGROUND: Compared with adult mesenchymal stem cells, yolk sac-derived MSCs of early embryo have stronger self-renewal capacity and plasticity. Moreover, they could differentiate into angioblast and hemopoietic stem cells during embryonic development and trigger embryonic angiogenesis and hemopoietic tissue development.

背景：与成体间充质干细胞相比，来源于早期胚胎的卵黄囊间充质干细胞有更强的自我更新能力和可塑性，且在胚胎发育过程中可分化为成血管细胞和造血干细胞，启动胚胎血管发生和造血组织发育。

Immunohistochemically, the tumor cells were strongly positive for α fetoprotein and α antitrypsin.

发生于心脏的卵黄囊瘤是极为罕见且高度恶性的，它的诊断主要依靠病理组织学及免疫组化检查。

Chickens colibacillosis is a focus or systemic infectious disease, which is caused by E.coii ,with complicated antigens, multiple serotype and various clinical symptoms such as salpingitis, synovitis, and so on. Colibacillosis often happens together with various diseases and has been spread everywhere in Haian county in different extent..

鸡大肠杆菌病乃是由大肠埃希氏菌所引起的局部或全身性感染的疾病，其抗原性复杂，血清型多样，临床症状和病理变化多变，包括大肠杆菌性败血症、大肠杆菌性肉芽肿、气囊炎、肿头综合症、腹膜炎、输卵管炎、滑膜炎、全眼球炎及脐炎、卵黄囊炎等。

Methods: We detected serum antibody of rattus,hare, wild boar,muntiacus reevesi ogilby, fox, dog and cattle with mCF method. SFGR were isloated from Ixodiodeas with Embryonate hens eggs and identified with mCF and PCR/RFLP.

鼠类、野兔、野猪、麂、狐狸、狗、牛血清学检测，采用微量室温补体结合法；病原分离：用鸡胚卵黄囊感染法分离SFGR，并用 mCF、PCR/RFLP技术对分离株进行鉴定。

Results Incidence of AFP-positive gastric carcinoma was 6.2%(87/1395). Sixty-three cases of AFP-positive gastric carcinoma were divided into four subtype: hepatoid type 22 cases (34.9％), fetal gastrointestinal type 15 cases (23.8%), and mixed type of the hepatoid type with enteroblastic differentiation to be 24 cases(38.1%), and yolk sac tumor-like type 2 cases (3.2％).

结果：AFP阳性胃癌的发生率为6.2％（87/1395例）。63例中依据其病理组织形态学特点和肿瘤组织内癌细胞AFP染色阳性表达，并对比3个月妊娠胚胎胃肠组织学的改变，将其组织学类型分为4个亚型：肝样型22例（34.9％），胎儿胃肠型15例（23.8％）和肝样型伴肠胚分化的混合型24例（38.1％）以及卵黄囊瘤样型2例（3.2％）。

The transforming growth factor-β superfamily, a large group of highly conserved growth factors including TGF-βs, activins and BMPs, regulate a wide variety of cellular functions such as proliferation, differentiation, apoptosis and migration. Signals from these growth factors are transduced by a group of Smad proteins. To date, there are nine vertebrate Smads, including the receptor-activated Smads , Smadsl-3, 5 and 8, the common mediator Smad4 and Smad4β, and the inhibitory Smads, Smad6 and 7. Signaling is initiated when the ligand induces assembly of a heteromeric complex of type Ⅱ and type Ⅰ TGFβ receptors. Then R-Smads are directly phosphorylated by activated type I TGF-β receptors.

在多种SMADS中，SMAD5令我们产生兴趣，基于三个原因：1、Smad5基因敲除胚胎中发现卵黄囊的异位造血以及CFU-GM祖细胞数目增加，表明SMAD5可能是早期造血发育的负向调控基因。；2、应用反义核酸封闭Smad5可以逆转TGF-β对祖细胞增殖的抑制效应，表明它可能介导TGF-β信号转导，后者的异常，包括某些SMADS的功能异常，和白血病紧密相关；3、Smad5基因定位在人染色体5q21，此区域的缺失和急性髓系白血病和骨髓增生异常综合症相关，因此，Smad5被怀疑为白血病抑制基因。

The hybrid between Brachymystax lenok and Hueho taimen were not a live in the past 2 years. However, the fertility and eyed rate of BH were significantly higher than that of HH and BB (P.05), while the hatching rate were significantly lower (P.05). The larvae died within 1 to 2 hours after hatching. It was observed that the tail of yolk-sac larve couldn't stretch around the yolk, and there were hyperemia in the middle and posterior segment of the tail. The reason why the hybrid between Brachymystax lenok and Hucho taimen couldn't snrvive might was the karyoplasms of the gametes from Brachymystax lerwk and Hucho taimen by distant hybridization were not compatible.

细鳞鲤×哲罗鱿的杂交经过2年多批次实验均未得到成活杂交子代，但在胚胎发育阶段BH的杂交受精率、发眼率均显著高于双亲自繁对照组(P.05)，但其孵化率显著低于双亲对照组(P.05)，BH杂交子代在破膜后1~2h内即死亡，刚破膜的仔鱼尾干中后段至尾鳍部分盘绕于卵黄囊表面不能伸展，且所有破膜仔鱼的尾干中后段均存在充血点，本研究认为，这种反交［细鳞鲑×哲罗鲑］子代不能成活的原因可能是由远缘杂交受精卵核质不相容所导致。

In her eyes, because that is the doorway toher heart * the place where love resides.

女人的漂亮必須從她的眼睛中去看，因為那是她心靈的窗戶和愛居住的地方

I will send some postcards to you.

我会向你发送一些明信片。