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动脉粥样硬化

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In the experimental group (transplanted with embryonic arcuate nucleus), the endothelial cells remained intact, and connected tightly with subendothelial tissue, occasionally twisted nucleus could be seen.

实验证明,在被毁损弓状核区重新植入胚鼠弓状核细胞后对动脉粥样硬化有明显恢复作用,从而证实下丘脑弓状核对动脉粥样硬化的形成具有重要调控作用。

The serums SM levels are closely related with the known atherogenic risk factors, and they are also an important risk for atherosclerosis.

血清SM水平和已知的致动脉粥样硬化危险因子密切相关,提示SM可能是导致动脉粥样硬化发生的重要因素。

OBJECTIVE: To compare the rheological properties of stress relaxation in normal and atherosclerotic animal model of ascending aorta, and to identify the effects of atherosclerosis on the stress relaxation properties of ascending aorta.

目的:比较正常和动脉粥样硬化动物模型升主动脉的应力松弛流变特性,确定动脉粥样硬化对升主动脉应力松弛特性的影响。

To compare ascending aorta creep characteristics of the normal and atherosclerotic animal model to identify the effect of atherosclerosis on ascending aorta creep characteristics.

比较正常和动脉粥样硬化动物模型升主动脉的蠕变特性,确定动脉粥样硬化对升主动脉蠕变特性的影响。

To test the hypothesis that concentration polarization of atherogenic lipids may occur in the arterial system and play an important role in localization of atherosclerosis, we simulated and measured in vitro the luminal surface concentration of low density lipoprotein in local stenosis at the distal end of carotid artery by number simulation and laser scanning confocal microscopy, then we designed carotid stenosis model to test the role of LDL concentration polarization in atherogenesis.

低密度脂蛋白(low density lipoprotein, LDL)浓度极化可能是动脉粥样硬化局灶性的重要原因,本文以狭窄血管远心端为研究对象,探讨LDL浓度极化对动脉粥样硬化发生、发展的影响。

We investigated the effect of the known hypocholesterolaemic and anti-atherosclerotic drug probucol on serum lipids, lipoproteins and atherosclerosis in fat-fed low density lipoprotein receptor deficient mice.

本实验研究了抗高胆固醇血症和抗动脉粥样硬化药物普罗布考对脂肪饲养低密度脂蛋白受体缺失小鼠的血清脂质,脂蛋白和动脉粥样硬化的影响。

The rate of scleratheroma of carotid and the intimae medial thickness is high with impaired glucose tolerance. Earlier period change of carotid atherosclerosis is already initiate in impaired glucose tolerance stage.

颈动脉内中膜增厚及粥样硬化斑块在糖耐量低减者中有较高的发生率,早期动脉粥样硬化改变早在糖耐量低减阶段就已经开始。

Moreover, in order to make clear whether IV infection touches off the cause and its pathogenesis of artherosclerosis inflammatory reaction. The study also uses IV of type A1 and A3 to infect repeatedly Jimpy mice with E gene defect, to observe AS histology change of Jimpy mice aorta and detect the change of IV antibody and inflammatory reaction medium (eg.TNF-α, IL-1) in Jimpy mice serum and express of monocyte chemotactic factor( MCF-1) and nuclear factor kB in Jimpy mice aorta tissue .

另外,为了弄清流感病毒感染是否是触发动脉粥样硬化炎症反应的发生原因及其机理,本研究还用A1、A3型流感病毒反复感染载脂蛋白E基因缺陷小鼠,观察小鼠主动脉的动脉粥样硬化组织学改变,并检测小鼠血清中流感病毒抗体、炎症反应介质(如TNF-a、IL-1等)变化情况以及小鼠主动脉组织中的单核细胞趋化因子-1(MCP-1)和核转录因子kB表达情况。

Methods To detect the serum CRP and serum lipid while in quiring the smoking status for278patients with cardio-vascular disease.

结果 CRP在吸烟与不吸烟组、动脉粥样硬化和非动脉粥样硬化组差异有显著性。

Methods To detect the serum CRP and serum lipid while in quiring the smoking status for278patients with cardio-vascular disease.Then analyed the CRP level among different groups.

方法通过对临床278例动脉粥样硬化和非动脉粥样硬化病人血清CRP和血脂的检测及吸烟情况的调查,应用SPSS统计软件进行差异分析,比较不同组间CRP水平。

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