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Preparation of ratiometric pH nanosensors and its appication in intracellular pH detection of the anti-tumor drugs treated Hela cells The ratiometric pH nanosensors that contained a pH sensitive indicator fluorescein isothiocyanate and a reference dye tris(2, 2′-bipyidyl) dichlororuthenium hexahydrate had been prepared with O/W microemulsion method.

利用该内参比pH纳米传感器尺寸小可以通过细胞的内吞而无损伤地进入细胞内的优势,进一步结合流式细胞学分析方法,对不同抗肿瘤药物作用的Hela细胞内的pH变化进行了分析,结果表明:不同抗肿瘤药物作用后的Hela细胞内pH的变化情况并不一样,有的作用后引起了细胞酸化,有的作用后引起了细胞碱化,有的作用后基本上不引起变化。

The material base of German political modernization was established under the leadership of the Junker, The bourgeois Junker was the main driving force in the process of German political modernization.

国内学术界对德国现代化进程中容克的保守作用论述较多,对其积极作用则认识不足。容克对政治现代化的阻碍作用被认为是其"保守"或"反动"作用的突出表现。

The function mechanism among the minerals and floatation drugs had been studied with the way of IR and academic calculation, which pointed out that absorption of G-4 on the surface of phosphorite belonged to physical and chemical types, but the chemical one was in the highest flight. Absorption of amine collector named GE-609 on the surface of quartz belonged to electrostatic and physical type. Distilled water could hardly wash the GE-609 down from the surface of quartz. Leading component of S-721 was the concentrated compound of naphthol sulfonic acid and formaldehyde. The compound had a stronger affinity to the Mg~(2+) on surface of dolomite than the Ca2+ on surface of phosphorite, which is the essential reason in the separation of phosphorite and dolomite. The leading components of soluble glass in function were HSiO3 hydronium and F^SiC^ colloid granule.

通过红外光谱测定以及理论计算的方法研究了选矿药剂与矿物间的作用机理,研究表明:脂肪酸捕收剂G-4对胶磷矿的捕收作用是以化学吸附为主、化学吸附与物理吸附共同作用的结果;胺类阳离子捕收剂GE-609在石英表面的吸附属于静电物理吸附,但很难用水洗的方法使GE-609从石英表面脱附;S-721主要成分为萘酚磺酸与甲醛的缩合物,萘酚磺酸与甲醛的缩合物对白云石表面Mg~(2+)的吸附明显强于对胶磷矿表面Ca~(2+)的吸附,这是胶磷矿与白云石分离的根本原因;水玻璃溶液中对石英起抑制作用的主要组分是HSiO_3~-和H_2SiO_3胶粒,水玻璃除对石英起抑制作用外,对矿浆还具有一定的分散作用。

Adopting normal rat or mouse, chronic bacteria and nonbacteria prostatitis model, prostate proliferation model, and other corresponding model, and through seting up different control group, we performed laboratoty investigation to turn out weather qianlieqingshu capsule can cure chronic prostatitis, depress prostate proliferation, activate blood circulation and remove stasis, antixidant, defervesce and ease pain.

实验方法:采用正常大鼠或小鼠、慢性细菌性及非细菌性前列腺炎模型、前列腺增生模型以及其他相应模型的大鼠或小鼠,并通过设立不同的对照组以进行前列清疏胶囊对大鼠慢性前列腺炎的治疗作用、抑制前列腺增生、活血化瘀作用、抗炎作用、解热作用以及镇痛作用的实验研究。

The most important postmortem processes include transport, test size sorting, mechanical breakage and erosion, test dissolution and so on. The author put forward two new concepts: foraminiferal test"breakage index" and"dissolution index" to quantitatively describe the postmortem processes, and applied them to the observation and experiment on test breakage and dissolution.

壳体的搬运作用、机械破坏作用和化学溶解作用是重要的死态过程,为定量描述这些作用本文提出&有孔虫壳体磨蚀度指数&&有孔虫壳体溶蚀度指数&等新概念,并进行了磨蚀度的统计和溶解作用的实验。

The simulation results show that the deformation of the stainless steel foil under buckling mechanism depends on the integration of the thermal stress and the pre-stress when the laser beam irradiates the foil.

研究发现,预应力作用下激光弯曲成形是热应力与预应力综合作用的结果,在预应力作用下激光弯曲成形效果显著增加。

It makes known that the forming of ore-bearing skarn is the same as that of mineral deposit, and has the same experience of having been affected by the primary sedimentatin which is relating to the hot-water deposition, the regional metamorphism, and the limiting remaking of local magmatic hydrothermalism, and is the result of synthetical action by multiple geological events.

可以看出,含矿矽卡岩的形成同矿床一样,经历了与热水沉积作用有关的原始沉积作用,区域变质作用和局部地段岩浆热液的改造作用,是多次地质事件综合作用的结果。

And ZNF397nf function as transcription repressors. The different transcriptional regulation activity of the nf isoforms and their interaction with the fu isoforms would contribute to the complexity of the transcription regulation. To further examine the biological function of interaction between different isoforms we also analyze the potential role of ZNF191 and ZNF434 on signaling pathway. We found that ZNF191fu can significantly enhance the HSE-luciferase activity, while ZNF434fu can enhance the AP1-luciferase activity, then we analyze whether the nf isoforms have impact on the fu isoforms.

而这些成员的nf剪接本与它们对应的fu剪接本的转录调控功能有所不同,其中ZNF191nf与ZNF434nf剪接本的转录调控活性相对它们的fu剪接本显著降低,呈现较弱的转录抑制作用,但ZNF447nf剪接本却呈现出显著的转录激活作用,同时ZNF397nf剪接本则表现出显著的转录抑制作用,ZNF396nf剪接本的转录调控作用与其fu剪接本相当。nf剪接本这种与fu剪接本不尽相同的转录调控活性以及能与fu剪接本互作的能力,大大增加了转录调控作用的复杂性,这使得通过少量的转录因子作用来实现众多基因时空表达的不同成为可能。

Bond length, total atomic charge, frontier molecualr obital energy, and Mullicken Bonding Population proclaimed that electron transfer ought to be possible from benzene to ammonium to form charge-transfer cpmplexes. The molecular obital coefficience showed that the p-π initeraction must be existed between alkali metal cation and benzene.

键长、原子净电荷、前线轨道能量和分子轨道系数、Mullicken成键布居等量子化学参数表明碱金属阳离子和苯环碳原子发生作用而形成电荷转移复合物,这种作用中包含p-π作用的形式。

At the same time, gene interaction was observed in some of characters, transgressive segregation gene interaction was observed in polygenes controlling length of axial root and thickness of root base ( 1cm), complementary gene interaction was significantly detected in nodule number of lateral root and dry weight of lateral root and nodule number of lateral root, but not detected or significant in the others.

控制主根长性状的多基因间存在互作,互作方式为重叠作用;控制主根粗(3cm)性状的基因间也存在一定的重叠作用,但是作用不明显;控制其他性状的基因都存在互作,表现为互补作用,但互补作用的强弱有差异。

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Since historical times,England ,where the early inhabitants were Celts, has been conquered three times .

从有历史以来,英国,在此地早期居住的是凯尔特人,已经被征服了三次。

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