二尖瓣闭锁不全

These women, ages 61, 72 and 74 years, receiving long-term pergolide therapy for Parkinson's disease or restless legs syndrome, had valvular abnormalities strikingly similar to those induced by fenfluramine, ergot derivatives, or carcinoid. All three had severe, unexplained tricuspid regurgitation; two had predominantly right-sided congestive heart failure; and two had moderate aortic and mitral valve regurgitation. Histology revealed surface fibroproliferative lesions with preserved underlying valve architecture. Carcinoid was excluded, and none of the patients had taken anorectic drugs or ergots other than pergolide.

这3位妇女年龄分别为61、72及74岁，都长期服用pergolide来治疗帕金森氏症或睡眠脚动症，而且也都有不明原因的严重三尖瓣闭锁不全，就像因fenfluramine、麦角衍生物，或类癌肿瘤所引起的瓣膜异常情形一样；其中2位主要有右心衰竭，2位有中度的主动脉及二尖瓣的闭锁不全，组织学检查显现表面有纤维增生性的损伤，但瓣膜的结构仍然还在；类癌是被排除在外的，而且这3位妇女除了pergolide之外，都不曾服用过厌食剂或麦角类药物。

Valvular heart disease, usually aortic and mitral insufficiency, can complicate a variety of systemic diseases.

瓣膜性心脏病，以主动脉瓣及二尖瓣闭锁不全为最常见，可使各种全身性疾病变得复杂。

Valvular heart disease , usually aortic and mitral insufficiency, can complicate a variety of systemic disease s

瓣膜性心脏病，以主动脉瓣及二尖瓣闭锁不全为最常见，可使各种全身性疾病变得复杂。

Mitral valve insufficiency ; Coronary disease ; Coronary artery bypass ; Cardiovascular surgical procedures

二尖瓣闭锁不全；冠状动脉疾病；冠状动脉分流术；心血管外科手术方法

A systolic murmur may indicate ventricular septal rupture or mitral insufficiency from acute MI.

收缩期杂音表明室中隔破裂或急性心肌梗死引起的二尖瓣闭锁不全。

Mitral valve insufficiency ; Field Ⅱ ultrasound simulation ; Blood flow imaging ; RF signals spectrum analysis

二尖瓣闭锁不全； Field Ⅱ超声模拟；血流成像； RF信号谱分析

Objective To investigate the effects of interleukin-1 β converting enzyme gene on the biologic characteristics of ovarian cancer cells.

目的 探讨白细胞介素-1 β转换酶的表达，对卵巢癌细胞生物学特性的影响。

Campylobacter: This illness is the most commonly identified cause of diarrheal illness in the world.

弯曲：这种病是最常见的原因查明腹泻病，在世界上。