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Objective This paper evaluates the importance of early diagnosis and systemic treatment of true hermaphroditism.

目的 探讨真两性畸形的早期正确诊断与合理治疗。

We herein report two cases of goats with sexual deformity.They had two systems of reproductive organs and the karyotype analysis showed mosaicism for their sex chromosomes,i.e.,60,XX / XY.The proportion of XX cell line was 42% and 54%,while XY cell line was 58% and 46%,respectively,in the two abnormal goats.

本文报道2例两性畸形的山羊,它们均具雌雄两套生殖器官,染色体组型分析显示它们均为性染色体嵌合体,核型为60,XX/XY,两头畸形山羊的XX细胞系的比例分别为42%和54%,XY细胞系的比例分别为58%和46%。

Fig 3 Male pseudohermaphrodite raised as a female,Preopera-tive and 7 days postoperatively

图3抚养为女性的男性假两性畸形,术前和术后7d

Methods The CT findings in 4 cases of female pseudohermaphroditism were analyzed retrospectively.

回顾性分析4例经手术及临床诊断为女性假两性畸形的CT表现。

Objective To evaluate the CT findings of female pseudohermaphroditism.

目的 评价女性假两性畸形的CT表现特点及其临床价值。

Objective To evaluate the CT findings of female pseudohermaphroditism. Methods The CT findings in 4 cases of female pseudohermaphroditism were analyzed retrospectively.

目的 评价女性假两性畸形的CT表现特点及其临床价值方法回顾性分析4例经手术及临床诊断女性假两性畸形的CT表现。

Objective To evaluate the diagnosis and treatment of female pseudohermaphroditism caused by 21-hydroxylase deficiency.

目的 探讨21-羟化酶缺乏(21-hydroxylase deficiency,21-OHD)致女性假两性畸形的临床诊断及治疗方法。

You've got male pseudohermaphroditism.

你患的是男性假两性畸形

DNAs from a group of sex chromosome abnormal patients〔46 XX male, 45 XO Turner's syndrome, 47 XXY klinelfter syndromes, 46 XX true hermaphrodite, 46 XY hermaphrodite, 47 XYY male, 48 XXXY male〕 was hybridized to ZFT using southern bloting method.

我们对一组性染色体异常的病人(46XX男性,46XX真两性畸形,46XY两性畸形,45XO Turner's综合症,47XXY Klinelfter综合症,47XYY男性,48XXXY男性)DNA,用ZFY探针进行了Southern印迹杂交。

The results showed that all of them could detect the presence of ZFY DNA sequences except a 46 XX"male"and a 46 XX hermaphrodite, our findings confirmed that Ferguson-Smith〔1966〕 forwarded the hypothesis that the X-Y intercharge model for XX maleness can be regarded as an abnormal exchange initaited in a region proximal to TDF and extending to the telomere,and,also strongly suggested that ZFY gene palyed an important role in sex determining of human.

结果除一例46XX两性畸形,一例46XX&男性&外,余均能检测到ZFY DNA序列(ZFY DNA序列存在于46XX真两性畸形和45XO Turner's综合症,在国内外尚未见报道)。证实了1966年,Ferguson-Smith提出的理论:在父源减数分裂期间,X-Y发生不等交换,导致Y染色体DNA插入性易位。XX男性是由于Y染色体上的TDF基因转移至X染色体上所致。

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