下锚

Results As shown in Western blot analysis, the presence of microsomes did not alter the molecular weight of TM-TNF , but it did result in the cleavage of the IL-2 signal peptide from S-TNFm,suggesting that the leader sequence of TNF might differ from the signal peptide of typical secretory protein in that it seemed not to have undergone cleavage during translation in the rough-faced endoplasmic reticulum. Further enzymatic analysis revealed that TM-TNF was converted into S-TNF through the effect of certain metalloproteinase. Conclusions These results suggest that the mechanisms of TNF-α production may be as follows: Activation of TNF-α producing cells by LPS leads to augmented transcription/translation of TNF-α gene, resulting firstly

实验结果提示17×103 S-TNF产生机制可能是：TNF产生细胞经LPS等激活后，导致TNF基因转录翻译增加，首先形成26×103 TNF，并借助其信号肽疏水氨基酸部分将之&锚定&在细胞膜，成为跨膜型TNF，介导细胞与细胞之间的生物学效应；在某些蛋白酶作用下，可将mTNF的&信号肽&切除，产生17×103分泌型TNF，释放至体液中，在局部或全身发挥作用。

Since historical times,England ,where the early inhabitants were Celts, has been conquered three times .

从有历史以来，英国，在此地早期居住的是凯尔特人，已经被征服了三次。

Bluetooth OBEX File Transfer Enables the sending and receiving of files on your phone via Bluetooth.

蓝牙OBEX文件移动允许经过蓝牙传送和接受文件。。。。