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Poptosis-inducing factor is a mitochondrion-localized flavoprotein with NADH oxidoreductase activity, which is encoded by the nuclear gene. Following induction of apoptosis, AIF is released from mitochondria and translocated to cytosol, and then to the nucleus. The mechanism of AIF translocation from mitochondria to nucleus is still unclear. It has been suggested that translocation is due to the presence of nuclear localization signal.

bstract： AIF(apoptosis-inducing factor)为位在粒线体内膜膜上之蛋白质，在正常细胞中，能够藉由维持电子传递链复合体I的稳定性，进而影响细胞能量的产生及自由基的清除，并且也会维持粒线体的构造；反之，当细胞遭受到不当刺激时，粒线体膜通透性改变，使得原本存在於粒腺体间质中之AIF，被释放出来，进入细胞核内造成DNA片段化，进一步促进细胞凋亡。

To the question of unclear base structure framework, the disputed geological horizon and the region deposition system, and under cognition of the distribution of flysch, hydrocarbon reservoir-forming mode of the central uplift belt and south ramp region in the sag, this thesis expatiates the Peleogene structure and the deposition evolution characteristics of the Hhuiming sag, based on the theory of structural geology, sedimentology, petroleum geology, synthetically using the data of geology, geophysics and test analysis, and analyses hydrocarbon reservoir formation mode and its control factor, connect with the petroleum geology achievement. It gives a scientific reference to enhance the exploration effective in the research area.

针对研究区基地构造格局认识不清，地质层位、区域沉积体系认识存在争议，洼陷浊积岩分布情况、中央隆起带及南部斜坡带成藏机理有待深化认识等问题，论文以构造地质学、沉积学、石油地质学等理论为指导，综合利用地质、地球物理和测试分析等资料，开展惠民凹陷古近纪构造与沉积演化特征研究，结合石油地质成果分析油气成藏模式及控制因素，为有效提高研究区勘探成效提供科学依据。

The outlook of Fortis is still unclear.

富通接下来的情况似乎仍不明朗。

But it was unclear yesterday whether the announcement will lead to a full-blown investigation.

但目前还不清楚，昨日的声明是否将导致一项全面的调查。

But this condition smuggles in a functionalist theory of concepts (via a functionalist theory of concept possession), and if we are prepared to buy that, it is unclear why we also need the primary intension theory.

但是，这是偷偷把概念的功能主义理论介入进来了（经由拥有概念的功能主义理论），如果我们准备用这个，不清楚的是，为什么我们也需要基础内涵理论。

If you gabble, you'll end up feeling worse as you know you're being unclear to your audience or to the person you're in a conversation with.

如果你说话含糊不清，那么你会感到更不自信，因为你知道你的听众或者你的交谈对象没有听清你在说些什么。

In recent years, retrograde adriamycin sensory ganglionectomy has been used in treatment of trigeminal neuralgia and has obtained good therapeutic effect The mechanism of action, particularly, of the toxic effects with different mechanism methods and choice of doses for muscle cells and nerve cells is still unclear.

阿霉素为常用的抗肿瘤药，近年来应用阿霉素治疗三叉神经痛的文献报道较多，且已获得较好的效果，但其治疗机制尚不十分明确，尤其是对肌细胞及神经细胞的毒性作用机制特点及不同的给药方式和剂量选择尚不够明确。

With only one week before the new rules are to go into effect, it is unclear if American computer companies will comply.

因为这一新规定在一周前才开始实行，所以还不清楚美国的电脑公司是否会遵守。

Because of the low amount of berberine in most goldenseal products, it is unclear how effective the whole root or root extracts would be in treating diarrhea.

由于黄连素的含量很少，大多数白毛莨的产品，目前还不清楚如何有效整根或根提取物将在治疗腹泻。

At this point, it is unclear what actually happened on the golf course.

在这一点上，目前还不清楚究竟在球场上。

Since historical times,England ,where the early inhabitants were Celts, has been conquered three times .

从有历史以来，英国，在此地早期居住的是凯尔特人，已经被征服了三次。

Bluetooth OBEX File Transfer Enables the sending and receiving of files on your phone via Bluetooth.

蓝牙OBEX文件移动允许经过蓝牙传送和接受文件。。。。