查询词典 tunnel effect

The entrance section of FuXi Double-arched Tunnel is modeled in the fact of factual shallow buried and unsymmetrical pressure condition. Adopting the three heading construction method to simulate twelve kinds of construction projects, confirm reasonable construction orders and left and right tunnel face interval, systematically analyze and research the changing law of the tunnel deformation and surrounding rock stress in soft and cracked condition of surrounding rock,bring forward pertinent advices against construction disease; Build the deep buried tunnel model in middle section of tunnel , separately adopt the central heading bench cut benching method and the central heading full cross method to simulate ten kinds of construction projects, establish the reasonable construction orders, sidestep length and tunnel face interval, which are due to the deep buried tunnel, systematically analyze and research the change law of the tunnel deformation and surrounding rock stress in the section with good surrounding rock condition, bring forward the reasonable construction projects which can make sure of construction safety and save construction time; Because the central wall is disturbed many times during constructing process, its displacement and stress distribution is very complex.

富溪隧道进口段依照实际的浅埋偏压状况建立模型，采用三导洞法开挖模拟了12种方案，确定了合理的施工顺序和左右主洞掌子面错距，系统地分析研究了软弱破碎围岩浅埋偏压段施工的隧道变形和围岩应力变化规律，提出了防止施工病害的针对性建议；洞身段按深埋隧道建立模型，分别采用中导洞台阶法和中导洞全断面法模拟了10种方案，确立了适合深埋隧道的合理施工顺序、台阶长度和掌子面错距，系统分析研究了围岩较好深埋段施工的隧道变形和围岩应力变化规律，提出了兼顾施工安全和节省工期的合理施工方案；由于受到多次扰动，中隔墙的位移和应力变化规律较为复杂，通过对各种方案的对比分析，得出了中隔墙在施工不同阶段的位移变化规律、应力变化规律和应力分布规律，尤其对于浅埋偏压段隧道施工时中隔墙位移和应力变化规律做了深入研究，提出了合理的施工建议。

The selection of geological prospecting in different stages(initial-prospecting, detailed-prospecting)(2)the selection of geological prospecting in the deep-laid and shallow-laid of tunnel project (3)the selection of geological prospecting of tunnel projecting in different geological conditions Finally, the author summed up main problems needing to be solved in tunnel engineering geological prospecting as follow:(1)differentiate stratum and find out the depth and thickness of different stratums in the tunnel section (2)find out geological structure and existence situation of fault, broken zone and weak plane (3)find out weathering level of bed rock to classify surrounding rock combining speed materials (4)differentiate stratum structure of the entrance of tunnel to judge the stability of it (5)find out existence situation and performance of ground water (6)situations of other harmful geological phenomenon In view of above problems and classification of surrounding rock, the author showed principles of rational choosing of methods in geological prospecting and counted disperse range of physical character parameter value in different petrosal character, getting achievements as follow:(1)summarization of effect, merits and demerits of different geological prospecting methods in the tunnel geological investigation (2)method selection and arrangement principle of tunnel engineering geological prospecting in different geological conditions and prospecting stages (3)According to previous experience and cases, the author concluded the物性parameters most in use ,and showed the basis of selecting geological prospecting methods in different geological conditions.

论文中用几个应用实例来说明：(1)不同勘察阶段物探工作的选用；(2)深埋、浅埋隧道工程物探工作的选用；(3)不同地质条件隧道工程物探工作的选用。最后总结归纳出隧道工程物探所需要解决的问题主要有：(1)划分地层，查明隧道通过剖面的各地层深度与厚度。(2)查明地质构造，隧道轴线段有无断层、破碎带、软弱层面等。(3)查明基岩风化程度，从而结合速度资料进行围岩分级。(4)划分洞口地层结构，判断洞口稳定性。(5)查明地下水赋存情况及其活动动态。(6)其他不良地质现象存在情况。针对上述需要查明的地质问题与计算围岩分级情况，论文提出合理选用物探方法的原则，并统计了物性参数值在不同岩性中的分布范围。得出以下研究成果：(1)总结出各物探方法在隧道地质调查中的作用和优缺点。(2)得出不同地质条件下和不同勘察阶段，隧道工程物探方法选择和布置的原则。(3)根据以往工作经验和事例，对常用的物性参数进行了归纳总结，同时介绍了不同地质条件下物探方法选择的依据。

The stable clones are further identified by RT-PCR and Western blot; 6 MTT assay is used to investigate the effect of ZNRD1 on the cell growth of cells (AGS, SGC7901, MKN28, NIH3T3, GES-1); 7 Soft agar assay is used to investigate the effect of ZNRD1 on the clonality of cells (AGS, MKN28); 8 Nude mice assay is used to investigate the effect of ZNRD1 on the cell growth of gastric cancer cells (AGS, MKN28); 9 Flow cytometry is used to investigate the effect of ZNRD1 on the cell cycle distribution of cells (AGS, MKN28, NIH3T3, GES-1); 10 Flow cytometry is used to investigate the effect of ZNRD1 on the cell apoptosis of cells (AGS, MKN28, NIH3T3); 11 MTT assay is used to investigate the effect of ZNRD1 on the drug sensitivity of cancer cells (SGC7901, SGC7901/VCR, HL-60, HL-60/VCR) in vitro; 12 SRCA is used to investigate the effect of ZNRD1 on the drug sensitivity of gastric cancer cells (SGC7901, SGC7901/VCR) in vivo; 13 Flow cytometry is used to investigate the effect of ZNRD1 on adriamycin accumulation of cancer cells (SGC7901, SGC7901/VCR, HL-60, HL-60/VCR); 14 Transmission electron microscope is used to investigate the effect of ZNRD1 on the sensitivity of SGC7901 cells towards drug-induced apoptosis; 15 Flow cytometry and DNA ladder assay are used to investigate the effect of ZNRD1 on the sensitivity of cells (SGC7901, SGC7901/VCR, HL-60/VCR) towards drug-induced apoptosis; 16 Microarray is used to investigate the profiling of ZNRD1-responsive genes in gastric cancer cells (AGS, MKN28, SGC7901, SGC7901/VCR); 17 RT-PCR and Western blot are used to identify the results of microarray; 18 Reporter gene assay is used to investigate the effect of ZNRD1 on the transcriptional activity of cyclin D1; 19 Reporter gene assay is used to investigate the effect of ZNRD1 on the transcriptional activity of MDR1; 20 Kinase assay is used to investigate the effect of ZNRD1 on the activity of cyclin E-CDK2 kinase; 21 The antisensenucleic acids of p21 is used to inhibit the expression of p21, and flow cytometry is used to investigate the effect of p21 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 22 The antisensenucleic acids of p27 is used to inhibit the expression of p27, and flow cytometry is used to investigate the effect of p27 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 23 Liposome is used to up-regulate the expression of Skp2, and flow cytometry is used to investigate the effect of Skp2 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 24 Western blot is used to investigate the effect of ZNRD1 on the stability of Skp2 and p27 in gastric cancer cells; 25 MVD assay is used to investigate the effect of ZNRD1 on the angiopoietic activity of gastric cancer cells; 26 ELISA is used to investigate the effect of ZNRD1 on the expression of VEGF165 in gastric cancer cells; 27 The roles of DARPP-32 in MDR of gastric cancer cells are investigated using gene transfection, MTT assay, SRCA, flow cytometry and DNA ladder assay.

应用杂交瘤技术制备ZNRD1的首个单克隆抗体；2）利用RT-PCR、Western blot和免疫组化检测ZNRD1在胃癌组织、胃炎组织、正常胃上皮组织、胃癌细胞和正常胃组织上皮细胞中的表达；3）构建ZNRD1的小干扰RNA载体，并测序鉴定；4）利用脂质体将ZNRD1的真核表达载体及其空载体转染胃癌细胞（AGS、SGC7901、MKN28）和小鼠成纤维细胞（NIH3T3），G418筛选后进行鉴定；5）利用脂质体将ZNRD1的小干扰RNA载体及其空载体转染药敏胃癌细胞（SGC7901）、正常胃组织上皮细胞（GES-1）、对长春新碱耐药的胃癌细胞（SGC7901/VCR）、药敏白血病细胞（HL-60）、对长春新碱耐药的白血病细胞（HL-60/VCR），G418筛选后进行鉴定；6）利用MTT实验检测ZNRD1高/低表达对细胞（AGS、SGC7901、MKN28、NIH3T3、GES-1）生长的影响；7）通过软琼脂克隆形成实验检测上调ZNRD1对AGS、MKN28细胞克隆形成能力的影响；8）通过裸鼠成瘤实验检测上调ZNRD1对AGS、MKN28细胞体内成瘤性的影响；9）通过流式细胞仪分析ZNRD1高/低表达对细胞（AGS、MKN28、NIH3T3、GES-1）的细胞周期的影响；10）通过流式细胞仪分析上调ZNRD1对细胞（AGS、MKN28、NIH3T3）的凋亡的影响；11）通过MTT实验检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60、HL-60/VCR）体外药物敏感性的影响；12）通过肾包膜下移植法检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR）体内药物敏感性的影响；13）通过流式细胞仪分析ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60、HL-60/VCR）内阿霉素蓄积和泵出的影响；14）通过透射电镜检测上调ZNRD1对SGC7901细胞凋亡敏感性的影响；15）通过流式细胞仪和DNA梯度试验检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60）凋亡敏感性的影响；16）通过基因芯片检测ZNRD1高/低表达对胃癌细胞内基因表达谱的影响；17）利用RT-PCR、Western blot对基因芯片的结果进行鉴定；18）利用报告基因实验检测ZNRD1对cyclin D1的启动子活性的调节作用；19）利用报告基因实验检测ZNRD1高/低表达对MDR1的启动子活性的调节作用；20）利用激酶试验检测ZNRD1对cyclin E-CDK2 激酶活力的影响；21）利用反义核酸技术抑制p21的表达；通过流式细胞仪检测抑制p21对ZNRD1介导的细胞周期阻滞的影响；22）利用反义核酸技术抑制p27的表达；通过流式细胞仪检测抑制p27对ZNRD1介导的细胞周期阻滞的影响；23）利用脂质体转染法上调Skp2的表达；通过流式细胞仪检测上调Skp2对ZNRD1介导的细胞周期阻滞的影响；24）利用Western blot检测ZNRD1对p27和Skp2的蛋白稳定性的影响；25）利用微血管密度实验检测ZNRD1对AGS、MKN28细胞裸鼠移植瘤微血管形成的影响；26）利用ELISA检测ZNRD1对AGS、MKN28细胞培养上清和移植瘤匀浆中VEGF165含量的影响；27）利用脂质体转染法、MTT实验、肾包膜下移植法、流式细胞仪和DNA梯度试验检测新耐药相关分子DARPP-32对细胞（SGC7901、SGC7901/VCR、对阿霉素耐药的胃癌细胞SGC7901/ADR）多药耐药表型的影响；利用脂质体转染法和MTT实验检测下调ZNRD1对DARPP-32介导的胃癌多药耐药的调控作用。

Though the load analysis on the tunnel roof wall-rock in the fault footwall tunnel, this paper solves the problem of the tunnel support of tunneling through the great fault; and though the load analysis on the corresponding wedge of the lower abandoned tunnel, solves the problem of the influence of the lower abandoned tunnel on the upper tunnel floor.

通过对断层下盘巷道顶板围岩的受力分析，解决了煤巷掘进过大断层的巷道支护问题；通过对下部废巷道对应的楔形体的受力分析，解决了下部废弃巷道对上部巷道底板的影响问题。

In this paper, resource and feature of three-dimensional data model to the arch tunnel and interior installation are mainly researched; design thinking of the arch tunnel model is given out; algorithms of three-dimensional model about tunnel body and the joint part of the adjacent to tunnel body are achieved; in addition, relevance algorithms of texture mapping technology to interior in tunnel body and three-dimensional model of interior installation of tunnel are also researched.

主要研究了拱形巷道及其内部设备三维建模的数据来源和特点；给出了拱形巷道建模的设计思路；研究了实现巷道体和相邻巷道体之间连接处三维建模的算法；另外也研究了实现巷道体内部纹理贴图技术及巷道内部设备三维建模的相关算法；研究了实现三维巷道漫游的算法。

A large 3D numerical model of forked tunnel is set up and different construction processes are simulated by D-FEM. Through analyzing displacement, stress and damage yield zone of tunnel surrounding, the optimum construction process that left tunnel excavates ahead of right tunnel 32 m is determined, left tunnel and right tunnel excavate synchronously is proposed.

建立了分岔隧道大型三维数值模型，采用弹塑性损伤有限元D-FEM模拟了分岔隧道不同的施工过程，通过分析施工过程中隧道围岩的位移、应力和损伤屈服区，最终确定采用左洞超前右洞32m，左右洞同步开挖的施工方法。

Methods: The muscular branches originating from the three parts(radial tunnel part, supinator tunnel part and post-tunnel part) of PIN were observed on 30 sides upper limb specimens.The dimensions and morphology of the radial tunnel, supinator tunnel and the arcade of extensor carpi radialis brevis muscle were observed and measured with caliper, and the surface projection of the entrance and exit of the ST were located.

30侧尸体上肢标本，将PIN分为3段(即桡管段、旋后肌管段和旋后肌管后段)观察其肌支的分支情况；用卡尺对桡管、旋后肌管和桡侧腕短伸肌腱弓的形态和大小进行了观测，并对ST入口和出口的体表投影定位。

Results show that gas release in gassy sand will cause the additive deformation of tunnel and additive stress of the shield segment, and make important impacts on the global displacement of tunnel but little influences on the stress of shield segments and the relative displacement of tunnel. It is inclined to arouse the differential settlement and cracks on the tunnel so as to cause hazardousness. Re-accumulating of the gas can also produce additional stress and the additive resilience, but it can be ignored in practical engineering because the influence degree is small. The shallow gas in reservoirs is appropriate to be discharged before construction of the subway tunnel.

研究结果表明：气体释放将引起隧道产生附加变形和管片附加应力，浅层气体释放对地铁隧道结构应力和结构相对变形影响较小，而对隧道整体位移影响较大，易引起不均匀沉降，导致隧道裂缝或断裂，进而引发危险；气体重新回聚时，隧道产生的附加应力和回弹位移量较小，工程中可不予考虑；地铁隧道施工前，宜对浅层气体进行预先排放。

The observation results reveal the difference between surrounding rock pressures of shallow tunnel calculated by exiting methods and test results is large, pressure figure seems cat ear, surrounding rock pressure of deep tunnel belongs to clastic pressure, the test result is consistent with result by modified KAKE formula, the invert stress properties of shallow tunnel and deep tunnel are different, the axial force of lattice girder is at pressure in majority, and the stress of second lining is relatively small in loess highway tunnel.

实测结果表明：现有浅埋隧道围岩压力公式计算结果与实测结果偏差较大，其分布呈"猫耳朵"形状；深埋隧道围岩压力属形变压力，其实测值与修正卡柯公式计算结果较为一致；深埋与浅埋隧道中仰拱的受力性态有所不同；格栅拱钢筋轴力以受压为主；黄土公路隧道二次衬砌受力相对较小。

Baziling forked tunnel along Shanghai-Chengdu Expressway in construction is an unsymmetrically loaded tunnel. Construction process of forked tunnel is very complex because the forked tunnel includes twin-bore section and small clear spacing section. So, it's important for forked tunnel to adopt appropriate construction process.

正在施工的沪蓉西高速公路八字岭分岔隧道属于偏压隧道，而且分岔隧道包括连拱段和小净距段，施工过程转换复杂，因此，采用正确的施工方案对于隧道的稳定性非常重要。

I was just taking her hand, to help her out of a car, and I knew it.

我只是握着她的手，扶她下车，但我知道这一切。

China and South Korea have excoriated Japan over its approval of new school books which they say whitewash the atrocities committed during Japanese occupation, and anti-Japanese protests have been held in Chinese cities. The lingering bitterness over Japan's past imperialism still threatens to mar relations between the big East Asian powers

中国和韩国强烈谴责日本通过新的中学历史教科书，他们认为这一教科书掩盖了日本在其占领期间所犯下的残酷暴行，反日抗议活动在中国数座城市发生，历史上日本帝国主义制造的痛楚无法被忘却，这有可能破坏东亚强国间的关系。