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Objective: To study changes of subtype of T lymphocytes and ACTH in different trait-anxiety levels of new recruits under acute stress.

目的：研究急性应激对不同特质焦虑新兵的T淋巴细胞亚群及ACTH的影响。

We have determined the crystal structure of the human A2A adenosine receptor, in complex with a high-affinity subtype-selective antagonist, ZM241385, to 2.6 angstrom resolution.

我们已经在复杂的具有高亲和性亚型选择性拮抗剂ZM241385中，已经确定了以2.6埃分辨率的人类A2A腺苷受体晶体结构。

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis. CA inhibition may not be an important contributor since CA II expression and CA activity was intact in anhidrotic mice treated with topiramate.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗(来源：A44B8787C论文网www.abclunwen.com)功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

Methods:(1)Immunofluorescence and electron microscopic autoradiography were used to detect the expression and distribution of somatostatin receptor 2 subtype in NCI-H446 cells.

方法①应用免疫荧光技术及电镜放射自显影技术检测体外培养的小细胞肺癌NCI-H446细胞中生长抑素受体亚型2的分布与表达特性。

The anatomic subtype included type A 18 (85.7%),type B 3 (14.3%),and no type C in the records.All cases were associated with large PDA and VSD,some also with ASD,bicuspid or unicuspid aortic valve,and subvalvular aortic stenosis.

所有病例均合并粗大动脉导管未闭及大型室间隔缺损，其它伴发畸形包括继发孔房间隔缺损、主动脉瓣单瓣或两瓣畸形、主动脉瓣下狭窄。

Aim: To study the effect of EEG biofeedback therapy in treatment of different subtype of ADHD .

目的：比较脑电生物反馈治疗注意缺陷多动障碍不同亚型的疗效。

The results showed that the contents of M 1 and M 2 receptors decreased,the abilities of learning and memory in mice markedly increased and the contents of M 1 subtype of muscarinic acetylcholinergic receptors increased while that of M 2 subtype showed no changes.

结果表明，模型小鼠海马M1和M2含量显著降低，天泰Ⅱ号可显著提高模型小鼠的学习记忆能力，并显著增加其海马M1受体亚型的含量，但对M2无明显影响

Single-subject design was used in this study, five students with ADHD (three of them were identified as the subtype of ADHD-IA and others were belonging to the subtype of ADHD-HI) were included in this study to verify the effects of attention in different sitting positions (upright sitting position and forward-leaning sitting position).

此研究使用单一受试者研究法，将五位参与研究的个案（包括3位ADHD-IA型与2位ADHD-HI型的注意力缺失过动症学童）摆位在不同的坐姿下进行比较，以探讨前倾坐姿对ADHD学童注意力的影响。

The results of this study included:(1) Forward-leaning sitting position showed positive effect toward the students with ADHD, especially for the students with the subtype of ADHD-HI;(2) If the educational environment meets the need of the students with ADHD, the problem of attention deficit will be decreased with the growth of age;(3) The modified educational environments in the study were not showed obvious effects toward each student with the subtype of ADHD-IA, the educators should provide more useful learning strategies to improve their attention problems to consider the inside events.

本研究的结果包括：(1)前倾坐姿对ADHD学童的影响是正向的，尤其是诊断为ADHD-HI类型的学童在前倾坐姿下的测试正确率明显高於正中坐姿下的测试正确率；(2)若教育环境的配置可以符合ADHD学童的需求，注意力缺失的问题会倾向随著年龄的增长而逐渐改善；(3)本研究中环境配置的修改并没有对每个ADHD-IA类型的学童产生显著的影响，教育者应该提供更有效的学习策略来改善此类型学童沉溺於内在事件思考的问题。

Since historical times,England ,where the early inhabitants were Celts, has been conquered three times .

从有历史以来，英国，在此地早期居住的是凯尔特人，已经被征服了三次。

Bluetooth OBEX File Transfer Enables the sending and receiving of files on your phone via Bluetooth.

蓝牙OBEX文件移动允许经过蓝牙传送和接受文件。。。。