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The median time to achieve a neutrophile count of 0.5×109/L was 10 days after the last dose of chemotherapy in regimen A,and the time was 16 days in regimen B.The average SLEDAI decreased from 9.2 to 4.4,and the proteinuria decreased from to (0~+) in 3 weeks after the treatment.Two cases with complication of hemolytic anemia and 1 with thrombocytopenia before the treatment recovered to normal or nearly normal hemogram respectively.Among these 5 cases,1 patient had a short time improvement during the therapy,but died 50 days later because of refractory thrombosis of renal vein; 4 other patients achieved complete or partial remission within 5~16 months follow-up.

结果方案1从CTX结束算起，中性粒细胞恢复到0.5×109/L平均需10d，方案2从Ara-C结束起，中性粒细胞恢复到0.5×109/L需16d；治疗3周时 SLEDAI平均从9.2降至4.4，尿蛋白从降至(0~+)，合并有重度难治性贫血或血小板减少者，治疗后血红蛋白或血小板分别恢复正常或接近正常；方案2治疗的1例由于肾血管血栓形成未能控制，病情短暂好转后再度恶化，1个月后死于DIC和肾功能衰竭；另4例随访5~16个月，病情基本控制。

Objective To probe the effect of applying a regimen of Dexamethasone, Nitrogen Mustard, Defibrase and Chinese medicine, combined with Chlorambucil, on treatment of refractory nephrotic syndrome which were dependent on predimisone.

目的 探讨苯丁酸氮芥结合"四联"疗法对激素依赖型难治性肾病的治疗作用。

A 55-year-old male nonsmoker with multiple myeloma refractory to chemotherapy was admitted to the hospital for autologous stem-cell transplantation.

一位55岁因多发性骨髓瘤接受过化疗的非吸烟男性患者同意住院接受自体干细胞移植。

To analyze the clinical application and effect of three therapy methods in treatment of refractory bone nonunion.

［目的］比较分析3种方法治疗四肢难治性骨不连的临床疗效。

The experience in building large-volume coke oven is summed up in terms of quality management of refractory, building of coke oven body,door,gas offtake pipe,fire bed as well as problems relevant to the building of coke oven body.

从耐火材料的质量管理、焦炉本体的砌筑、炉门、上升管、火床的砌筑及与焦炉本体砌筑相关问题等方面总结了焦炉砌筑的经验。

Objective To study the change of intracellular free Ca2+ in the oocyst when it melanized and to find out the relationship between the melanized oocyst and its intracellular level of free Ca2+ in a Plasmodium-refractory strain of Anopheles dirus.

目的研究大劣按蚊蚊胃的约氏疟原虫卵囊黑化时卵囊内Ca~(2+)的变化，探讨疟原虫感染不易感蚊种时卵囊黑化与囊内Ca~(2+)的相互关系。

New progress has been got in dephosphorizing of Fe concentrates owing to the development of RA-31 and DA-18 with success. mineral processing ; refractory iron ores ; oolite ; high-phosphorus iron ores ; iron increasing and phosphorus reducing ; flotation reagents

根据鄂西铁矿石的特点进行了选矿药剂及相应的浮选和絮凝选矿工艺的研究，研制成功了RD-31捕收剂和DA-18选择性絮凝剂，采用磁选-脱泥-反浮选工艺流程，对武钢矿业公司科技处提供的鄂西铁矿混合矿样(WE-1样)进行

Rats with CHF were divided randomly into two groups, one group was injected dexamethasone(1mg /kg) intramuscularly at the first and forth day respectively,the other group was injected equi-volume saline likewise, and observing the changes of symptoms of rats with CHF; measuring rats hemodynamics index including blood pressure, heart rate and left ventricular end-diastolic pressure 4 days later. Part 2: To measure every group rats myocardialα1、β1、β2、β3-AR density by immunohistochemical method ,and to understand the AR density changes .Taking the first part rats'myocardium tissues for testing myocardialα1、β1、β2、β3-AR density and 5 normal rats for normo-contrast group and taking gray scale of slice as AR density. Part 3: The study enrolled 35 patients with DCHF. Patients were included if they had orthopnea and refractory edema due to acute DCHF that was severe and had taken more 1 week hospitalization and intravenous therapy in addition to diuretics.

观察心衰大鼠的症状，4天后对两组大鼠进行血流动力学检测，检测指标包括血压、心率和左室舒张末压；第二部分：取第一部分实验动物大鼠的心肌组织，并取5只正常大鼠的心肌组织作为正常对照，用免疫组化法检测大鼠心衰前后及糖皮质激素治疗前后大鼠心肌组织肾上腺素能受体α1、β1、β2、β3受体的变化，取镜下切片的灰度值反应受体的密度；第三部分：研究对象为临床难治性心衰病人35例，病人的选择标准包括由于急性失代偿的心力衰竭出现的端坐呼吸，难治性水肿，患者病情严重，住院超过1周，包括利尿剂之外药物的静脉治疗。

Antiphospholipid syndrome should be considered in the differential diagnosis of papilledema, and oral acetazolamide is an important adjunct therapy to anti- coagulation in cases of refractory papilledema to protect the optic nerve from potential damage which results in blindness.

马来亚大学医学院眼科；马来亚大学医学院眼科；马来亚大学医学院眼科；马来亚大学医学院眼科；马来亚大学医学院神经科

The model can be used to investigate the expression of Pgp in the brain of refractory epilepsy rats.

该模型可以用于研究难治性癫疒间脑内Pgp的表达。

The quality of both red and white wine depends very much on the wine maker talent and on the quality of the grapes.

他的红酒和白酒的品质，根据酿造者的能力和葡萄的质量，各有差异。

No, I don't want to get drunk before my next match.

" "不，我不想让我的下一场比赛前喝醉了。