查询词典 rabies

Neutralizing potency of the patent recombinant anti-rabies virus McAbs, SO57 and SOJB,have been investigated broadly to different rabies virus strains in various animal models.100% Chinese Hamsters could be protected by 100IU/kg SO57 against China prevalent street rabies virus named SBD.We firstly established the mouse model to simulate human postexposure prophylaxis by rabies virus and found SO57 had the same function with HRIG against CVS or three China typical street rabies viruses.However,HRIG could not 100% protect the mice challenged with SBD street virus,rabies virus vaccine alone could not save life from rabies virus infection.The cocktail containing SOJB and SO57(1:1) did not do better than SO57 alone.

用不同的动物模型研究了具有专利的重组人抗狂犬病病毒单克隆抗体SO57、SOJB对不同狂犬病病毒株的中和作用，100IU/kg的SO57能100%保护被中国街毒株SBD攻击的中国仓鼠；首次用小鼠模型模拟人体被狂犬病病毒攻击后的治疗情况，在小鼠被CVS及中国街毒代表株攻击后，SO57与HRIG具有相近的对小鼠的暴露后保护作用；同时结果显示HRIG对SBD株攻击的保护率不能到达100%，仅使用疫苗是不能对感染病毒的小鼠百分之百的保护；SOJB与SO57 1：1联合使用未显示比SO57单独使用更好的保护效果。

In this study, the cDNA fragments of G-L intergenic region and polymerase activity module in L gene of two street rabies virus were cloned and sequenced. The nucleotides sequence of these cDNA fragments mentioned above and their deduced amino acid sequence were compared with that of rabies virus strains, rabies-related virus strains and other Rliabdoviridae published previously. The result show that the homology of nucleotide sequence of G-L IGR among MRV, DRV is 83.3%, compared with other rabies-related virus strains, the homology of G-L IGR is between 58.3%-91.7%. the length of G-L IGR of rabies virus is different in Rhabdoviridae.

本实验对狂犬病病毒野毒株MRV、DRV的G-L间隔区以及L基因聚合酶活性部位进行了克隆和测序，将所测定的结果和推定的氨基酸序列与国内外公开发表的狂犬病病毒其它固定毒株、野毒株和同科不同属的病毒的相应部分进行了分析比较，结果表明MRV、DRV G-L IGR核苷酸序列的同源性为83.3％，与其它毒株的同源性在58.3％～91.7％之间；狂犬病毒G-L间隔区序列的长度在弹状病毒科不同病毒属之间有所不同。

Facts as increasing number of dog raising, having not been injected with rabies vaccine and antirabies serum timely or full course after exposure, unstrictly controlling the quality of rabies vaccine as well as lacking good cooperation in different official department on rabies control might serve as factors responsible for the recurrent increase of human rabies.

养犬数增加、没有及时全程使用狂犬病疫苗和抗血清、疫苗质量把关不严以及缺乏不同部门间的合作是流行回升的因素。

The number of rabies infections increase these years,because there is no universal investigation in China, so it is unsure about the epidemicsituation of rabies in China. It is essential to study the molecular epidemiology ofstreet rabies virus isolated from the nature in order to prevent rabies infection andunderstand different inquilinous bodies of virus in different areas.

中国自2000年以来狂犬病的流行呈逐年上升的趋势，由于中国尚未开展大面积普遍的狂犬病流行病学调查，所以对中国境内狂犬病的流行情况还不明确，为了有效防制狂犬病，非常有必要对自然界分离的狂犬病街毒进行分子流行病学研究，以了解不同地域不同宿主病毒的流行特点。

In addition, 190 cases of rabies have been bitten for rabies vaccines and anti-rabies serum treatment of pregnant women and 185 infants born alive after one year follow-up, and with rabies has not been bitten by a comparison of babies born to pregnant women, found that spontaneous abortion is the former 4.2%, respectively, and the latter 5.6%, 0.5% pre-placental and 1.6%, 1.6% in diabetic pregnant women and 1.3%, stillbirths 1.6% and 1.5%, 0.5% in children with birth defects and 1.0%, low birth weight 2.6% and 9.9%.

另外，对190例被狂犬咬伤进行狂犬疫苗和抗狂犬病血清治疗的孕妇和185名出生后成活的婴儿进行一年随访，并与未被狂犬咬伤的孕妇所生婴儿进行比较，发现自发性流产分别是前者4.2%和后者5.6%、胎盘前置0.5%和1.6%、孕妇糖尿病1.6%和1.3%、死胎1.6%和1.5%、小儿出生缺陷0.5%和1.0%、低出生体重2.6%和9.9%。

There are two primary forms of rabies: urban rabies, spread by nonimmunized domestic dogs and cats and rural rabies spread by the skunk, fox, raccoon, bat, and occasionally livestock.

他们是两个主要的类型：市内的病毒，扩散到没有免疫的家庭狗和猫，乡下的病毒扩散由臭鼬，狐狸，浣熊，蝙蝠，偶尔是家畜。

Rabies virus, the etiologic agent of fatal neurological disease, is composed of five stuctural proteins, both of the glycoprotein and the nucleoprotein are believed the decisive factors for rabies diagnosis and classification and for rabies neurotropic, pathogenicity and antigenecity.

狂犬病毒由五种结构蛋白组成，其中NP对狂犬病的诊断和分类；GP对狂犬病毒的组织嗜性、致病和免疫保护都起着决定性的作用，并且分离自不同宿主或不同地理位置的狂犬病毒之间存在着NP和GP抗原性差异，研究这种差异并结合流行病学资料有助于发现流行来源的线索。

Bats have neither lice nor fleas, but they carry more exotic life forms, such as germs associated with Rabies (a strange little animalcule that actually lives in the brains of mammals including humans.—we can imagine therefore that the Rabies germ is closest to art of all life-forms.), Cholera, and Dysentery.

蝙蝠身上既没有虱子也没有跳蚤，但他们带来了更独特的生物，比如狂犬病菌（一种以哺乳动物包括人类的大脑为生存环境的微生物-----我们由此还可以想象这种狂犬病菌比其他任何一种生物都更接近艺术），霍乱和痢疾。

To understand rabies antibody and the status of autoimmunity after vaccination , provide scientific basis for rabies control and prevention.

了解狂犬疫苗接种后抗体的产生情况，掌握疫苗接种后的自身免疫状况，指导狂犬病防治工作。

In order to rich rabies virus gene bank, sequencing and analyzing parts of the two rabies virus street strains isolated from different animals in China.

本研究为了丰富我国狂犬病基因库，对我国不同动物中分离到的两个野毒株进行基因组部分序列的测定和分析。

The teacher likes the honeymouthed little girl very much.

老师很喜欢这个嘴甜的小姑娘。

Mr. Notker Bien's interests are traveling, spending quality time with the family and long-distance-running.

诺特卡·柏恩先生热爱旅游，长跑，以及和家人一起共度美好时光。