查询词典 potent

Highly active, small-molecule furin inhibitors are attractive drug candidates to fend off bacterial exotoxins and viral infection. Based on the 22-residue, active Lys fragment of the mung bean trypsin inhibitor, a series of furin inhibitors were designed and synthesized, and their inhibitory activity toward furin and kexin was evaluated using enzyme kinetic analysis. The most potent inhibitor, containing 16 amino acid residues with a Ki value of 2.45×10~(-9) M for furin and of 5.60×10~(-7) M for kexin, was designed by three incremental approaches.

本论文研究活性多肽类似物的设计、制备和功能，分为四个部分，采用多肽固相和液相合成的方法，分别合成了活性多肽绿豆胰蛋白酶抑制剂Lys片段长链16肽、天花粉胰蛋白酶抑制剂、癌胚抗原肽、甜味肽等一系列类似物，并测定了这些类似物的生物活性，有以下新的研究结果：1、furin酶抑制剂的设计、制备和功能；2、芳香氨基酸芳环之间的π-π共轭能部分补偿二硫键的作用；3、癌胚抗原肽Gly4被L-Pro替代可增加与HLA-A2分子的结合；4、肽键对甜味肽保持甜味是必须的。

It must be potent wine to make a wood-elf drowsy; but this wine, it would seem, was the heady vintage of the great gardens of Dorwinion, not meant for his soldiers or his servants, but for the king's feasts only, and for smaller bowls, not for the butler's great flagons.

只有烈酒才能灌倒一个森林精灵，不过这种酒，我们会看到，是出自多卫宁大葡萄园的浓烈红酒，本来不是给国王的仆役或者卫兵喝的，而是只供给国王的宴会，而且应该用小杯喝，不该象管家这样用大瓶灌。

Opinion: Whilst Taiwan had enjoyed technological and pilot training advantage over the numerically superior Chinese air forces for many years, this edge has eroded and reversed in recent years with the advent of large numbers of Flankers and J-10 fighters, as well as the almost unnoticed evolution of the underrated J-8-II into a potent modern fighter.

观点：虽然台湾一直享有技术和飞行员培训的优势数值优于中国空军多年来，这一优势已经削弱和扭转近年来，随着大批Flankers和J - 10战斗机，以及近注意演变低估的J - 8 -二成一个强大的现代化的战斗机。

Pigments potent and air temperature are are more important than other factors. The color changing of foliage trees leaf resulted from these comprehensive factors, We must fully respect them in landscape design. Meanwhile, we should make of the bionomics and ecologic habitus of these trees, and make sure to let them show vivid colors and the most beautiful landscape effictiveness in urban environment, ensure the landscape designs more scientific and artistic.

观叶树种的叶色是在许多因素综合作用下发生变化的，在利用观叶树种进行园林景观设计时必须充分考虑影响观叶树种叶色的各种因素，同时对观叶树种的生物学特性和生态习性有深入的了解，使其在城市环境中达到最鲜艳的颜色，产生最佳的景观效果，使园林植物造景更具科学性和艺术性。

Results: fops had inhibitory effect on o 2 production in vitro, having a 50% of inhibitory concentration (ic50) of 3.866×10-6 g/ml, and a weak inhibitory effect on h2o2 production with a ic50 of l.668×10-3 g/ml but showed a potent inhibitory effect on the various free radicals produced by "respiratory burst" of human leukocyte. fops (20, 40, 80 mg/kg) increased the sod activity in myocardial tissue, liver and kidney of mice and decreased the mda content of myocardial tissue, liver, kidney and spleen of mice.

结果：在体外阿里红多糖可有效的清除o 2，其ic50为3.866×10-6；对h2o2的清除作用很弱，但能抑制人血嗜中性粒细胞&呼吸爆发&产生的多种自由基，ic50为1.668×10-3；阿里多红糖（20、40、80 mg/kg）可明显增加小鼠心脏和肝脏中sod的活性，其中剂量为40、80 mg/kg的阿里红多糖可明显增加肝脏中sod的活性，同时各给药组均可明显减少小鼠心脏、肝脏、肾脏和脾中mda的含量，与对照组相比较差异有统计学意义（p.05）。

In this study, the model drug, TSB-9, is a poorly water-soluble mixture extracted from Garcinia hanburyi Hook. f.. Gambogic acid is one compound which was proved potent cytotoxicities against various cancer cell lines by irreversible arrest in G2/M phase of the cell cycle in Gamgoge.

中文摘要在本研究中我们所使用的模式药物为TSB-9，是一种萃取自藤黄中的混合物，其成分之一，Gambogic acid在许多的药理研究中被认为对於癌细胞细胞周期中的G2期以及M期会产生不可逆的中止，所以有抑制肿瘤增生的功效。

With his instantly recognizable voice, potent lyrics and shards of brilliance, Ghost Style remains the name to remember in Hip Hop on this side of the Pacific Rim.

他的声音那么特殊，以至于过耳难忘，尖刻的歌词打破天真的幻想，Ghost Style这个名字，在嘻哈界早已传到大洋彼岸。

Is a powerful aural mix of club, commercial, and street style beats, all of it straight from the heart of Hong Kong. Ghost Style stretches his lyrical reach even further with 'M.I.C.', waxing lyrical on topics ranging from the chemistry lathered streets of Hong Kong to the territory's politics, bad boys, party girls, and just about anything else worth keeping real in HK. Ghost Style calls these slices of HK life aural movies his 'exaggerated fiction', and his vocal range – from crispy kid to low-key baritone – brings his stories to life. With his instantly recognizable voice, potent lyrics and shards of brilliance, Ghost Style remains the name to remember in Hip Hop on this side of the Pacific Rim.

音乐盛宴，弥漫着商业元素与街头风格，正带着浓浓的Ghost Style味道Ghost Style发挥他的作词天赋，用流畅如水一般的歌词描述着各种主题，在香港街头掀起如泡沫般化学效应政治话题，小混混，夜店流莺，各种香港地下的真实场面被描述得淋漓尽致Ghost Style把这些香港社会的剪影称作是他&夸张的虚构&，他的音域可以从清脆的小屁孩腔转到低沉磁性的男中音，唱着这些如他自己生活一般的点滴故事他的声音那么特殊，以至于过耳难忘，尖刻的歌词打破天真的幻想，Ghost Style这个名字，在嘻哈界早已传到大洋彼岸

In the summer, the inch-long sluggish, fat rat-tailed maggots of the hovering flies, which feed upon decaying liquid substances, will develop in these potent brews as an indication that the liquid is biologically ready to be used.

夏季，盘旋的苍蝇繁殖出寸长的、行动缓慢的、肥胖的鼠尾蛆。这些鼠尾蛆以腐烂的液体物质为食，会在有效的酿造物中发育。一个迹象表明，生物学上可以使用这种液体。

That increased metabolism would, in turn, generate more oxygen-rich molecules of a type known as free radicals, which are potent inducers of mutation.

代谢速率的增加反过来会产生更多的富氧分子，即自由基。后者这是一种诱发突变的蛋白质。

Since historical times,England ,where the early inhabitants were Celts, has been conquered three times .

从有历史以来，英国，在此地早期居住的是凯尔特人，已经被征服了三次。

Bluetooth OBEX File Transfer Enables the sending and receiving of files on your phone via Bluetooth.

蓝牙OBEX文件移动允许经过蓝牙传送和接受文件。。。。