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A new design model for shield lining segments, beam-discontinuous joint model, is described in this paper. And based on the new model, the distribution mode and value of the loading pressure on the lining segments are back analyzed using the measured data of segment pieces such as axial force and bending moment etc. In addition, a partial-peripheral ground spring model is compared with a whole peripheral one in the backward analysis.

本文围绕盾构衬砌管片的设计模型与压力荷载分布问题，首先概述了一种新的设计模型--梁-接头不连续模型，在此基础上，利用管片内力的现场实测值，来反演确定作用在衬砌结构上的压力荷载的分布模式与大小，同时，运用反演分析技术对局部和全周地层弹簧作用模型进行了比较。

PART Ⅱ IMMUNOPATHOLOGICAL EVIDANCE OF SIALIC ACID STRUCTURE IN CAMPYLOBACTER JEJUNI AS THE CRITICAL ANTIGEN TO INDUCE PERIPHERAL NEUROPATHY To demonstrate the critical role of NANA structure in the pathogenesis of allergic peripheral neuropathy induced by Campylobacter jejuni and provide immunopathological evidence to confirm the supposition of molecular mimicry and cross-immunity between CJ LPS and gangliosides in nerve.

LPS免疫后第2周实验豚鼠的免疫血清中，抗LPS IgG抗体滴度均明显增高，第3周达高峰，第5周仍维持在峰水平，野生株和突变株LPS免疫血清中的抗-野生株LPS IgG抗体滴度较各自免疫前分别增高8倍和4倍，抗-突变株LPS IgG抗体滴度则较各自免疫前分别增高6.5倍和15倍；(2)全身免疫后第3周和第5周，野生株LPS免疫血清中检测到较免疫前增高6倍的抗-GM1 IgG抗体，而NANA缺失的突变株LPS免疫血清中一直未检测到抗-GM1 IgG抗体；(3)野生株LPS免疫组中有17.3％的坐骨神经原纤维发生以轴索变性为主（占65％）的免疫性损伤，与突变株LPS免疫组和对照组比较均有显著性差异。

Results: The risk factors for leukemic transformation and early death were bone ache, Hb＜30 g/L, dysplastic peripheral blood polymorphs, RAEB,RAEB-T of MDS subtype, blast of bone marrow and peripheral blood＞5%,with advancing myelofibrosis, ALIP,-7/7q-+8 and cytogenetic abnormalities at more than two chromosomes.

结果：剧烈骨痛、Hb＜30 g/L、外周血粒系发育异常、RAEB、RAEB-T MDS亚型、骨髓或外周血原始细胞＞5%、伴发MF和ALIP、-7/7q-，+8染色体异常或复合染色体异常为MDS预后不良因素。

However, the cytotox-ic dugs cant selectively kill the cancer cells without any side -effects, the decrease of peripheral blood WBC for myleosuppression caused by cytotoxic dugs contribute to the limitation of regular chemotherapy. Evidence was provided that cisplatin and cyclophosphamide used for ovarian cancer caused apoptosis in several in vivo tumors. For the reasons above, in our study, we detected the apoptosis of total peripheral blood WBC in patients with ovarian cancers before and after chemotherapy.

然而，由于化疗药物的非选择性组织杀伤引起的骨髓抑制而导致的末梢血白细胞减少，已经成为限制化疗剂量和按期进行规范性化疗的重要障碍，研究已证实卵巢癌的常规化疗方案中的顺铂及环磷酰胺能在多种肿瘤组织中诱导凋亡。

Ningbo World-metal stamping machinery is Taiwan's veteran peripheral manufacturers, professional manufacture and sale of peripheral automation punch line equipment, including air Tape feeder, high-speed roller Tape feeder, electronic control Tape feeder plane, terminal or feeder, NC Wheel Tape feeder, rack Correction of the machine, precision-corrected, microcomputer dead-detection, Die security detection devices, photoelectric Guarding hand, high-speed punch at NC computer speakers and precision, such as whole-Tape feeder.

宁波世庆五金机械是台湾老牌冲压周边厂家，专业制造与销售冲床周边自动化系列设备，包括空气送料机、高速滚轮送料机、平面电子控制送料机、端子收料机、NC滚轮送料机、料架兼矫正机、精密矫正机、微电脑下死点检出器、模具安全检出装置、光电护手、高速冲床隔音箱及NC电脑精密整平送料机等。

Pinout: C High-performance 32-bit RISC Architecture C High-density 16-bit Instruction Set C Leader in MIPS/Watt C Little-endian C Embedded ICE (In-circuit Emulation) 8-, 16- and 32-bit Read and Write Support 256K Bytes of On-chip SRAM C 32-bit Data Bus C Single-clock Cycle Access Fully Programmable External Bus Interface C Maximum External Address Space of 64M Bytes C Up to Eight Chip Selects C Software Programmable 8/16-bit External Data Bus Eight-level Priority, Individually Maskable, Vectored Interrupt Controller C Four External Interrupts, including a High-priority, Low-latency Interrupt Request 32 Programmable I/O Lines Three-channel 16-bit Timer/Counter C Three External Clock Inputs C Two Multi-purpose I/O Pins per Channel Two USARTs C Two Dedicated Peripheral Data Controller Channels per USART Programmable Watchdog Timer Advanced Power-saving Features C CPU and Peripheral Can be Deactivated Individually Fully Static Operation: C 0 Hz to 75 MHz Internal Frequency Range at VDDCORE = 1.8V, 85C 2.7V to 3.6V I/O Operating Range 1.65V to 1.95V Core Operating Range -40C to +85C Temperature Range Available in 100-lead TQFP Package

M5L8253P-5引脚说明： C型高性能32位RISC架构C高密度以MIPS /瓦C小端C十六位指令集C领袖嵌入式冰8 - 16 -位和32位的读写支持256K的片上SRAM的 32位数据总线C单时钟周期存取字节完全可编程的外部总线接口C最大的外部地址空间的64M字节多达8个C芯片选择C软件可编程8位外部数据总线8级优先级，独立可屏蔽，向量中断控制器C四外部中断，其中包括一个高优先级，低延迟中断要求32个可编程I / O口线三通道16位定时器/计数器C三个外部时钟输入C两多用途I / O引脚每通道2个通用同步C两专用外设数据控制器通道每个USART可编程看门狗定时器先进的节能特性 CPU和外设可停用独立全静态工作中：C 0 Hz至75 MHz的频率范围内的VDDCORE = 1.8，85℃2.7V到3.6VI / O的操作1.65V到1.95V范围核心工作电压范围在- 40C至+85 C温度范围内使用的100引脚TQFP封装

However, when the 3 individual outcomes (myocardial ischemia, stroke and peripheral vascular disease) were evaluated separately, only the relative risk reduction for peripheral vascular disease was effectively reduced:(stroke 7.3%, MI _3.7% and PVD 23.8%) The trialists attributed the discrepancy in the stroke group to the heterogeneity of the disorder, a correct but frequently overlooked observation.

然而，当我们分别对这三类患者结局（心肌缺血，卒中和周围血管病）单独分析时发现，仅周围血管病患者的相对危险降低率减少有显著意义（卒中组7.3％，心肌缺血组-3.7％，周围血管病组23.8％）。

Some conclusions are drawn as follows: The total tendency of socles is basin-shaped settlement which is bigger in the middle position socles than the peripheral position socles before the pile foundation underpinning. Pile foundation underpinning augments the differential settlements. After soil excavation, middle position socles rebound obviously owing to unloading action, which lessens the differential settlements between middle and peripheral position socles.

从沉降分析的结果可以看出：桩基托换前，地基总的沉降趋势是中间部位柱脚大于周边部位柱脚的&盆式沉降&；桩基础托换后，柱脚处的沉降差进一步增大；土方开挖后，由于下层土被&卸载&，中间部位柱脚处的地基明显回弹，使得中间部位柱脚与周边部位柱脚的沉降差出现了减少的趋势。

Results The response rate was 52.4% in patients with NP, 41.7% in those with VP, The main toxicity was myelosuppression including apparent decrease of white blood cells and platelets. The other toxicity included abdorminal distension constipations peripheral neuropathy (myalgia、peripheral neuritis) which were more severe in group of VP than those in NP group.

结果：NP组总有效率为52.4%(22/42)，其中完全缓解1例；VP组总有效率为41.7(15/36)，毒副反应主要为骨髓抑制，以白细胞、血小板下降较明显，其次为腹胀、便秘及末梢神经毒性，在VP组较为严重(P.05)。

Among them, by resisting the line , peripheral intensive coefficient of eyes and peripheral three major key elements that are blown up for the plain noodles of density of powder charge of eyes line minimumly.

这其中，又以最小抵抗线、周边眼密集系数和周边眼线装药密度为光面爆破的三大要素。

Objective: To study the effect of polycythemia on blood oxygen saturation.

裴蕾目的：观察RBC剧增而引起的高粘血症对血氧饱和度的影响。

Based on SIMPLER algorithm in the curvilinear body-fitted coordinates, the calculations were performed for Pr=0.7, Re=10~1000 on non-orthogonal non-staggered grids which are generated by elliptic equation systems.

采用曲线坐标系下压力与速度耦合的SIMPLER算法，数值研究了周期性渐扩渐缩波纹通道内脉动流动与换热情况，流动Re数的范围为10~1000，Pr数为0.7。