查询词典 oncogene

Objective: To explore the clinical significance of c-erbB-2 oncogene amplification in ovarian carcinoma.

目的：探讨卵巢癌c-erbB-2癌基因扩增的临床意义。

It baa boon indicated that the oncogene and anti-oncogone are closely related to the development and progression of cancer.

研究表明，肿瘤的发生和发展与癌基因和抑癌墓因有着密不可分的关系。

Most experts still believe that these tumors continue to be 'oncogene addicted' to EGFR, he said.

多数专家仍认为，这些肿瘤继续对突变的 EGFR '癌基因依赖'，他说。

The transcription level of c-Ha-ras oncogene and the content of P21ras in those exposed to chrysotile treated in advance with three kinds of chemicals mentioned above were significantly lower than those in untreated.

在上述3种化合物预处理的温石棉组，HEL细胞 c-Ha-ras癌基因的转录水平及P21ras蛋白含量均明显低于未处理温石棉组。

1,After transfected the mutated mtDNA of colorectal carcinoma,the mtDNA D-loop region of the transfected cells displays new mutation points.2,The external source pieces of the mutated mtDNA can integrate to nuclear genome after transfection.3,There's no differences in apoptosis between combinations after transfected the mutation of mtDNA in NIH3T3 and LST cells.4,The mutated mtDNA may affect the action mechanism of occurrence and development in colorectal carcinoma through affecting its mtDNA mutation or integrating exogenetic mtDNA to its nuclear which may cause the abnormal expression of oncogene or anti-oncogene.

（1）转染突变的大肠癌细胞mtDNA后转染细胞的mtDNA均可发生多处的突变位点。（2）通过转染后突变的外源性的mtDNA可以整合到核基因组内。（3）突变的mtDNA转染LST细胞及NIH3T3细胞后，不影响转染细胞的凋亡改变。（4）mtDNA的突变可能通过影响体细胞mtDNA的突变和通过外源性mtDNA在核内的整合从而影响癌基因或抑癌基因的表达异常，从而参与肿瘤的发生发展。

1,After transfected the mutated mtDNA of colorectal carcinoma,the mtDNA D-loop region of the transfected cells displays new mutation points.2,The external source pieces of the mutated mtDNA can integrate to nuclear genome after transfection.3,There's no differences in apoptosis between combinations after transfected the mutation of mtDNA in NIH3T3 and LST cells.4,The mutated mtDNA may affect the action mechanism of occurrence and development in colorectal carcinoma through affecting its mtDNA mutation or integrating exogenetic mtDNA to its nuclear which may cause the abnormal expression of oncogene or anti-oncogene.

（1）转染突变的大肠癌细胞mtDNA后转染细胞的mtDNA均可发生多处的突变位点。（2）通过转染后突变的外源性的mtDNA可以整合到核基因组内。（3）突变的mtDNA转染LST细胞及NIH3T3细胞后，不影响转染细胞的凋亡改变。（4）mtDNA的突变可能通过影响体细胞mtDNA的突变和通过外源性mtDNA在核内的整合从而影响癌基因或抑癌基因的表达异常，从而参与肿瘤的发生发展。线粒体DNA；D―环区；突变；质粒；pcDNA3.1；转染

The hepatocyte growth factor receptor is encoded by the proto-oncogene c-met, which can be uncongenially activated through a chormosomal rearrangement that creates a hybrid oncogene tpr-met.

c-met是一种原致癌基因，其蛋白产物为肝细胞生长因子接受体，透过染色体转位可产生具致癌性融合基因tpr-met。

Our results suggest that coden 12 of the H-ras oncogene may be a specific target for the mutagenic activation by tobacco smoke, and smoking is an important factor in the induction of H-ras oncogene mutation.

提示H-ras基因可能是被烟草激活的一个特殊位点，吸烟是导致H-ras基因突变的重要因素。

Aim: To study the effects of 8-Br-cAMP on oncogene and anti-oncogene in human Hela cells.

目的：探讨8-Br-cAMP对Hela细胞癌基因和抑癌基因等表达的影响。

The occurrence and growth of tumor correlate with the activation of oncogene and the mutation and/or absence of anti-oncogene.

肿瘤的发生发展与癌基因的激活和/或抑癌基因的突变、缺失密切相关。

But in the course of internationalization, they meet with misunderstanding and puzzlement.

许多企业已经意识到了这一点，但在国际化的进程中，仍存在一些误区与困惑。

Inorder toaccomplish this goal as quickly as possible, we'll beteamingup with anexperienced group of modelers, skinners, and animatorswhosenames willbe announced in the coming weeks.

为了尽快实现这个目标，我们在未来数周内将公布与一些有经验的模型、皮肤、动画制作小组合作。