查询词典 mutations

Objective:To discuss the role of p53 gene mutations in thepathogenesis of hematologic malignancies.

目的：探讨p53基因突变在血液系统肿瘤发病及进展中的作用。

Experts say the SARS virus certainly will keep mutating, but they do not know whether those mutations will change the seriousness of the disease.

专家们说， SARS病毒肯定将会不断突变，但他们不知道这些突变是否会改变该病的严重性。

BRAF mutations were detected in 13 of the 26 nodal nevi, but in just 1 of the 26 adjacent controls 50% vs.

同时，我们给每个病例都用了与其匹配的邻近淋巴组织作为阴性对照。26例淋巴结色素痣中有13例检测到BRAF基因的突变，邻近对照的淋巴组织中只有1例检测到BRAF的突变

If the CGHT mutations somehow alter this region of chromosome 17 so that the SOX9 protein is overproduced in hair follicle stem cells, this would cause excessive hair growth, says Zhang.

张学称，如果 CGHT 患者的基因突变使17号染色体区域发生改变，进而致使毛囊干细胞中的 SOX9蛋白产生过剩，这样就会引起过多的毛发生长。

Methods Using polymerase chain reaction-restriction fragment length polymorphism method, we detected 63 samples taken from 63 cases (including 36 invasive squamous carcinoma, 7 carcinoma in situ, 20 papillomas) for 248 point mutations in p53 gene.

采用聚合酶链反应――限制性片段长度多态性（polymerase chain reaction-restriction fragment length polymorphisms，PCR-RFLP）方法，对63例患者的送检标本（包括36例浸润性鳞状细胞癌，7例原位癌，20例乳头状瘤）中p53基因248位点的突变进行检测。

Hybrids and mutations of the flower were seen as rarities and a sign of high status.

杂交和变异的郁金香被认为是稀有品种，也是高贵身份的标志。

Objective To investigate the influence of combined hepatitis B immune globulin and lamivudine treatment on hepatitis B virus surface antigen and polymerase overlapping gene mutations in HBV reinfected liver transplant recipients.

目的 探讨乙型肝炎免疫球蛋白和拉米夫定对肝移植术后HBV再感染患者的HBV S基因与P基因重叠区变异的影响。

AR signalling can be activated in HR tumours through several mechanisms. First, activation of intracellular signal transduction pathways can sensitize the AR to castrate levels of androgens. Also, mutations in the AR can change AR ligand specificity, thereby allowing it to be activated by non-steroids or anti-androgens. Finally, overexpression of the wild-type AR sensitizes itself to low concentrations of androgens.

HRPC的AR信号通路活化机制包括：胞内信号传导途径可以增加 AR对于去势治疗后低水平雄激素的敏感性；AR的突变也可改变其对于配体的选择，使得非甾体类激素甚至抗雄激素药物也能够激活AR；此外，野生型AR的过表达也促进了自身对于低浓度雄激素的敏感性。

Investigation in 308 family trios suggested a co-dominant X-linked inheritance and mutations were not found.

对308个三联体的家系调查表明这两个基因座符合X染色体共显性遗传，未发现突变。

Breast density is trumped only by age and certain gene mutations in the hierarchy of risk factors.

乳房密度是莫须有的，只有按年龄和某些基因的突变层次的危险因素。

The two-acre Dunbar Community Garden in Little Rock has served as a model for several years.

几年来，坐落于小石城，占地两英亩的邓巴社区菜园树立了一个标杆。

Jerry points to the jacket hanging in the bathroom. It's ruined, and unwearable What?

杰瑞指着洗手间里挂着的夹克，毁了，不能穿了）什么？