查询词典 mutation

Objective To evaluate the value of pancreatic juice in cytologic examination and PCR-SSP in detecting K-ras gene mutation for diagnosis of pancreatic carcinoma.

目的 评价胰液细胞学检测与聚合酶链反应―顺序特异性引物检测K-ras基因点突变诊断胰腺癌的价值。

K-ras mutation in pancreatic juice and serum CA 199 level are effective in dictators for recurrence and prognosis of pancreatic carcinoma. The analysis of muliti-gene is more valuable than that of single.

联合胰液中K-ras 12密码子点突变及血清CA 199检测可作为判断胰腺癌术后复发的有效指标，多因素分析对胰腺癌术后复发的判断更有价值。

Objective: To analyze the BRCA1 mutation from the paraffin embeded tissue of 231 patients with breast cancer in southern China.

目的：研究中国妇女BRCA1基因突变与遗传性、家族性和早发性乳腺癌的关系。

P. denasta harbored the three chlorotypes, two of which were characteristic of its two parental species respectively. The third chlorotype was extensively distributed in seven of the ten P. densata populations analyzed, and might represent a mutation type or have been derived from an extinct parent. Population differentiation of P.

TT和GC分别是油松和云南松种特异性叶绿体单倍型，而在高山松群体里则三种单倍型均有分布，而且TC单倍型广泛地分布在7个杂种群体中，该单倍型很可能来源于点突变或第三个已灭绝的亲本。rbcL基因检测到的高山松群体分化系数很高（G〓=0.533）。

Domenstic and abroad academicians have disclosed the influence mechanism of these factors from different aspects, including the gene polymorphism and gene mutation in genetics, which are a susceptible factor for cardiovascular complication in type 2 diabetes patients; the dysfunction of endotheliocyte, the metabolic disorder of lipid, and dysfunction of vascular smooth muscle, which can lead to the formation of arteriosclerosis;the formation of immune complex,which can also accelerate the destruction of artery paries;the sctivation of protein kinase C and the dysfunction of platelet, which may ultimately result in the formation of thrombus and influence the function of cadiac muscle cells.

其中主要包括：遗传学方面的基因多态性和基因突变，二者均是2型糖尿病合并心血管疾病的一个易感因素，内皮细胞功能障碍、脂质代谢异常及血管平滑肌细胞功能异常均可导致动脉粥样硬化的形成；免疫复合物的形成可加速动脉壁的破坏；蛋白激酶C的激活及血小板功能受损最终导致血栓形成并影响心肌细胞的功能。

The mutation of Parkin gene is one of the pathogenesis of early-onset Parkinson's disease.

Parkin基因突变是早发性帕金森病患者发病原因之一。

To detect the mutation of PINK1 gene in Chinese patients with early onset Parkinsonism by using DHPLC.

应用DHPLC技术对100例EOP患者进行PINK1基因突变筛查，对DHPLC筛查发现异常的PCR扩增片段进行DNA直接测序和分析。

It also demonstrated that mutation on the residues at hydrophobic patch or pocket affects the structure, stability and basic properties of the proteins.

然而，疏水斑区和疏水袋上的改变，却大大影响蛋白质结构、稳定性和基本性质。

Among carriers of FLNA mutation, the penetrance of the disease was complete in men and incomplete in women.

在FLNA变异的携带者中，该病的外显率在男性是完全的，而女性是不完全的。

Penetrance can be influenced by mutation-specific phenotypes and the potential modifying effects of the patient's own genetic and environmental background.

外显率则受突变特异表型和病人自身的遗传和环境背景潜在的修复效应所影响。

The teacher likes the honeymouthed little girl very much.

老师很喜欢这个嘴甜的小姑娘。

Mr. Notker Bien's interests are traveling, spending quality time with the family and long-distance-running.

诺特卡·柏恩先生热爱旅游，长跑，以及和家人一起共度美好时光。