查询词典 mutation

He number of TCR V(Vα equal s to 100 and Bβ equals to 30 ) is less than the one of lg Vh (Vh equals to 300),for TCR V is subject to negative selection of major histocompatibility complex according to the neutral theory We discussed that is somatic mutation or DNA rea rrangement the main force in producing antibody diversity and are there pseudoge nes in TCR V or not.

CR V的数目(V α为100，Vβ为30)远少于Ig VH(数目为300)，原因是前者受到主要组织相容性复合体的制约，即受到负选择，这与中性学说观点相一致。文章还讨论了体细胞突变和DNA重排对两类抗体多样性产生上的作用，并探讨了Ig VH和TCR V的假基因问题。关键词分子进化，协同进化，免疫球蛋白，T细胞受体，中性学说

This course presents the information that has been collected from studying genetic variation in model systems like nematode and drosophila for mutation studies.

本课程提供的信息是从研究模式系统的遗传变异获得的，这些模式系统是用来研究突变的，如线虫和果蝇。

It is not factual or logical to deduce human evolution according to Neo-Darwinism s minority mutation.

按照小群突变的新达尔文主义来推断人类进化，既缺乏事实根据，也有悖于逻辑推理。

Later, after the completion of the modern synthesis, the term neo-Darwinism would come to be associated with its core concept of evolution being driven by natural selection acting on variation produced by genetic mutation and recombination.

后来，现代综合论完成之后，新达尔文主义观念才与现代综合论的核心概念相结合。现代综合论的核心概念是，自然选择作用于基因突变和重组所产生的变异，驱动了进化。

In the new view, viz. Neo-Darwinism theory, product family development system is analyzed and the architecture of product family gene model is built. After analyzing the gene expression of product family model, the center-principle for product family gene model is proposed and its information hereditary mechanisms are clarified. The algorithms of transcription, retrotranscription, translation, direct-translation and mutation for information gene are presented.

从一个新的角度——现代达尔文主义学说对产品族设计系统进行了分析，在此基础上，建立了产品族基因建模体系结构，分析了产品族模型的基因表达，提出了产品族基因建模中心法则，并对其中各个信息遗传机制进行了详细的分析和论述，给出了相应的信息基因转录、逆转录、基因转译、基因直译以及基因突变的算法。

Results The mutation mouse model was established successfully, and inflammatory reaction such as bacterial infection、inflammatory cell infiltration、proliferation of fibroblast and neogenesis capillaries of neonatal mouse model can be observed with TEM in different stage.

结果 成功建立小鼠模型；在模型小鼠出生后的不同时段中，电镜下小鼠角膜基质内可见有细菌感染、炎症细胞浸润、成纤维细胞及新生毛细血管增生等炎症改变。

Although the derivatives have lower toxicity, the curative effects are often lower than that of nitrogen mustard. And the toxic-side effect of the derivatives, such as bone marrow inhibition, cross-resistance, and mutation are still serious.

然而不幸的是这一问题并未得以解决，新的氮芥衍生物的毒性虽然小于氮芥，但细胞毒作用常低于后者，并且发现新的衍生物仍有相当的毒副作用，如骨髓抑制，交抗，致突变作用等。

The results were as follows: The mutation rate could be increased effectively by the three treatments; the cooperation effect was better when TMV was treated by nitrous acid and heating.

采用高温、亚硝酸及两者的复合处理对烟草花叶病毒强毒株进行诱变，均可有效提高突变频率，而且复合处理还有较好的协同效应。

The variation information is harvested from public mutation and polymorphism databases, such as dbSNP (http:∥www. ncbi. nlm. nih. gov/SNP), HGVbase http:∥hgvbase.

变异信息主要从公共的突变和多态数据库中获取，比如OMIM(http：∥www.ncbi.nlm.nih.gov／omim)、dbSNP(http：∥www.ncbi.nlm.nih.gov／SNP)和HGVbase(http：∥hgvbase.cgr.ki.se)，多态数据均归于不同的基因位点。

It has opened a new way for the diagnosis and therapy of tumours, and also estab- lished the foundation for the carcinogenic mechanism research. In order to study the altered molecular events during laryngeal car- cinogenesis and elucidat the role of oncogenes in laryngeal carci- noma, we examined the Ha-ras and c-myc gene mutation and amplification by the polymerase chain reaction and molecu- lar hybridization technigues respectivly.

癌基因的研究是当前肿瘤领域内的重大课题，正在基础理论和临床医学中进行广泛和深入的研究，癌基因的发现为肿瘤的诊断和治疗开辟了新的途径，同时也为人类开始从分子水平来回答细胞癌变的本质问题，最终认识癌变机制奠定了理论基础。

The teacher likes the honeymouthed little girl very much.

老师很喜欢这个嘴甜的小姑娘。

Mr. Notker Bien's interests are traveling, spending quality time with the family and long-distance-running.

诺特卡·柏恩先生热爱旅游，长跑，以及和家人一起共度美好时光。