查询词典 mutation stop

All 21 exons with flanking intronic sequences, as well as a 263 bp fragment of the 5" flanking region, of GARS-AIRS-GART gene, were screened in the same five populations, by the method of PCR-SSCP analysis, combined with sequencing reactions. We detected 10 SNPs, C-179T from 5" flanking region, A5669G form exon 3, C6545Afrom exon 4, A7777G from intron 4, G10854T, C10867T, G10898T from intron 6, A16197G from intron 11, C21228T from intron 14, and C29686T from exon 21. These ten polymorphic sites were nominated as GARS1, GARS2, GARS3, GARS4, GARS5, GARS6, GARS7, GARS8, GARS9, and GARS 10, respectively. The mutation of C D A at GARS3 was a non-synonymous mutation, wh

其中外显子4中的6545处的c~A突变导致对应的氨基酸序列中的第173位氨基酸发生变异：天冬氨酸一谷氨酸；10个SNP位点依次命名为：GARSI、GARSZ、GARS3、GARS4、GARSS、GARS6、GARS7、GARSS、GARSg、GARS 10；(2)10个SN'P位点在不同的鸡种中的基因型分布差异显著(P.05)，进一步的方差分析显示，GASRI位点以及GARS3位点与肌肉肌昔酸含量之间存在着显著的关联；(3)在所检测的5个群体中GARsl位

The check of mutation of video camera lens that offerred a kind to be based on BP nerve network newly calculates a standard, this algorithm chooses pattern plate to match poor cent and histogram 2 times 2 times to differ cent to serve as a feature, those who use nerve network from organization, self-study mutation of camera lens of implementation of ability of be used to detects, detect in order to flash next will raise detected dependability.

提出了一种新的基于BP神经网络的视频镜头突变检测算法，该算法选取模板匹配二次差分和直方图二次差分作为特征，利用神经网络的自组织、自学习能力实现镜头突变检测，然后以闪光检测来提高检测的可靠性。

The group uses Big Blue transgenic animals and cell lines to study the mutagenic effects of mutagens, the relation between DNA damage and mutation, the effects of aging and diet on mutation.

该集团使用大蓝鼠转基因动物和细胞系来研究诱变剂的诱变效应，脱氧核糖核酸损伤和突变的关系，生物突变中年龄与饮食的影响。

Male sibs who inherit the mutation will be affected ; female sibs who inherit the mutation will be carriers and will usually not be affected .

继承突变的同胞兄弟将成为患者；继承突变的同胞姐妹将成为携带者，通常不会发病。

There were two genotypesin China Merino fecundity sheep,the BB and B+ mutation genotype was superior in Chinese merino fecundity sheep,the ewes with genotype BB and B+had 4.0 and 3.5 ovulations,genotype ++ had 1.56 ovulations averagely,The BB and B+ mutation genotypes were 2.44(P.01)and 1.94(P.01)ovulations more than with genotype ++ in the Chinese merino sheep.

绵羊的多胎是绵羊业多产、高产的基础。一般来说，家畜的繁殖性状是受多基因控制的数量性状，传统的选择方法对其遗传进展的改良是很慢的，世代间隔长。分子标记辅助选择为解决这一问题提供了新的方向和契机。

But when his group stratified the cohort by mutation status, they observed differences in risk reduction."These results also generate the hypothesis that the protection conferred by risk-reducing salpingo-oophorectomy against specific cancers may differ between carriers of BRCA1 and BRCA2 mutations," Dr. Kauff told attendees."We found that it is highly protective against BRCA -associated gynecologic cancer in both 1- and 2-mutation carriers." And in breast cancer, his team observed a protective effect in BCRA 2 mutations.

当他的团队统计研究对象的突变状态时，他们观察到风险降低的差异性；Kauff医师向与会听众表示，这些结果也产生了藉由风险降低的输卵管卵巢成形术，对特定癌症所提供的保护效果或许会因BRCA1和BRCA2载体突变而有差异的假设；我们发现对这两种载体突变可以高度有效地对抗BRCA有关的妇科癌症；至于乳癌，他的团队观察到在BCRA2突变有保护效果。

But when his group stratified the cohort by mutation status, they observed differences in risk reduction."These results also generate the hypothesis that the protection conferred by risk-reducing salpingo-oophorectomy against specific cancers may differ between carriers of BRCA1 and BRCA2 mutations," Dr. Kauff told attendees."We found that it is highly protective against BRCA -associated gynecologic cancer in both 1- and 2-mutation carriers." And in breast cancer, his team observed a protective effect in BCRA 2 mutations.

当他的团队统计研究对象的突变状态时，他们观察到风险降低的差异性；Kauff医师向与会听众表示，这些结果也产生了藉由风险降低的输卵管卵巢成形术，对特定癌症所提供的保护效果或许会因BRCA1和BRCA2载体突变而有差异的假设；我们发现对这两种载体突变可以高度有效地对抗BRCA有关的妇科癌症；至於乳癌，他的团队观察到在BCRA2突变有保护效果。

The mutation R778L is the most common mutation of ATP7B gene in Chinese WD patients.

经检索2790del3是ATP7B基因新突变类型。R778L是中国人最常见的突变类型。

Patients were divided into two groups, those with gene Arg778Leu mutation in one group and the others in another group. Try to analyse and explore the correlation between gene mutation and clinical manifestation in WD patients.

将检测到该位点有突变和该位点无突变的患者分别归为一组，并与临床资料进行相关分析，探讨该突变点与临床表现型的内在联系。

The method is just like the QuikChange site-directed mutagenesis method except for its special primer. This pair of primers is composed of a long primer and a short primer which is central overlapped.Both of the Tm of 5\'sequence in long primer and Tm of 3\'sequence in short primer are above 66℃.The Tm of short primer is almost half of that of long primer.It is convenient to perform insertion or substitution mutation of DNA fragments larger than 20bp,In addition,it is highly applicable in research about the deletion mutation of DNA fragments larger than 2000bp.

我们实验室一直在寻找一种简单高效的可以用于基因的删除、插入及替代突变的方法，通过大量研究和实验发现，可以使用一种基于反向PCR原理，使用全新的引物设计的突变方法——&COP&突变法，该方法采用与QuikChange点突变法相同的操作步骤，其策略是设计一对中心重合的引物，长引物的5\'端序列和3\'端序列的Tm值均不低于66℃，短引物Tm值约为长引物一半，且与长引物中心重合互补。

The teacher likes the honeymouthed little girl very much.

老师很喜欢这个嘴甜的小姑娘。

Mr. Notker Bien's interests are traveling, spending quality time with the family and long-distance-running.

诺特卡·柏恩先生热爱旅游，长跑，以及和家人一起共度美好时光。