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To clone new disease gene of CMT, many myelin and myelin-related gene had been analysised by homologue searching. Quaking mouse, one of the mutation mouse with the clinic feature similar to Trembler mouse (the gene mutation mouse of PMP22) with the characterization of demylination in both the central and the peripheral nervous system, its disease gene had just been cloned accession No.

为进一步克隆新的CMT致病基因，在分析出CMT已克隆的基因均为与髓鞘有关的基因后，通过筛选有关髓鞘基因，我们发现，quaking基因突变小鼠因髓鞘形成障碍而出现震颤，其中枢和周围神经均有脱髓鞘，类似于PMP22基因突变鼠"Trembler"的临床表现。

By comparing the body weight, immune organs index and response of lymphocytes to ConA, to analyze the effect of QKL on immunological system of normal mouse. Delayed type hypersensitivity mouse model was established by stimulation with dinitrofluorobenzene. By comparing spleen index and swelling rate of pathogenetic ear, to illuminate the immunoregulation of QKL in vivo. Polymicrobial sepsis mouse model was induced by cecal ligation and puncture. The cumulative survival rate was observed in QKL and NS groups. Results: QKL had no influence on body weight and spleen index of normal mouse, but it could significantly decrease thymus index and inhibit the immune response of lymphocytes to ConA.

连续皮下注射QKL 5 d，通过检测小鼠体重、免疫器官指数和淋巴细胞对ConA刺激的反应，分析QKL对正常小鼠免疫功能的影响；采用二硝基氟苯诱发小鼠耳朵肿胀，发生接触性皮炎，建立DTH模型，通过比较QKL与NS对照对小鼠脾脏指数和发病耳肿胀抑制率评价QKL体内对小鼠的免疫调节功能；采用盲肠结扎穿孔术后引起的多细菌性腹膜炎，建立小鼠脓毒症模型，通过观察QKL对小鼠存活状况的影响，评价QKL的免疫调节作用。

MethodsAnti-inflammation effect of wild and cultivated Polygonun capitatum were observed by mouse abdominal cavity capillary permeability increase test induced by acetic acid, mouse auricle swelling test induced by xylene, mouse pedal swelling test induced by carrageenin and cotton granuloma test in mouse.

方法采用醋酸致小鼠腹腔毛细血管通透性亢进、二甲苯致小鼠耳肿胀实验、角叉菜胶致小鼠足肿胀和小鼠棉球肉芽肿等实验进行抗炎实验，采用醋酸扭体法进行镇痛实验。

Studies on mouse nuclear transfer with adult male mouse ear fibroblast cells as donors In this study, C57BL/6 adult male mouse ear fibroblast cells and Kunming mouse MⅡoocytes were used as donors and recipients, respectively, to investigate the effects of different passages of donor cells and electrofusion times on the in vitro development of NT reconstructed embryos, when the oocytes were treated with 3% sucrose.

以成年雄鼠耳成纤维细胞为供体克隆小鼠的研究该研究以C57BL/6 成年雄鼠耳成纤维细胞为供体，昆明白小鼠MⅡ期卵母细胞为受体，研究了3%蔗糖处理卵母细胞去核后，供体细胞不同传代次数和电融合次数对核移植重构胚体外发育的影响。

Result: With a high cancer-inhibiting rate on the animal model having been transplanted the cancer, this medicine can remarkably restrain the growth of cancer cells cultivated in vitro and improve the life quality of mouse model, and also shows obvious promotion and enhancement function on the DTH ear-swelling of mouse with cancer, the proliferation of mouse spleen lymphocyte induced by ConA and the cytokine (TNF-α、IFN-γ) of mouse with cancer respectively. It can obviously decrease the adverse effects like weight reduction, damage of viscera and degradation of life quality caused by the chemotherapeutic medicines, and has a remarkable stimulation on the lymphocyte proliferation induced by ConA. It is also able to improve the ratio of SMMC-7721 cells in G0-G1 period and reduce the cell amount in G2/M period to cut down the possibility of stepping into the division period; additionally, it can obviously inhibit some cancer genes of the cancer cells and meanwhile up regulate the cancer-inhibiting gene.

结果：本品能明显抑制体外培养肿瘤细胞的生长，对在体肿瘤移植模型动物具有较高的抑瘤率，能明显提高模型小鼠的生存质量；对荷瘤小鼠DTH耳肿胀、ConA诱导的小鼠脾淋巴细胞增殖、荷瘤小鼠细胞因子（TNF-α、IFN-γ）呈现明显的促进或提高作用；能显著减少化疗药所引起的小鼠体重降低、脏器损害以及生存质量下降等不良作用；本品含药血清对ConA诱导的淋巴细胞增殖具有明显的促进作用；能提高SMMC-7721细胞G0-G1期比例，降低G2/M期细胞数目，而减少其进入分裂期；对肿瘤细胞的多个癌基因具有明显的抑制作用，同时上调抑癌基因等。

Car walls and car door hairline stainless steel, 1 car operation panel in front wall with micro touch buttons, position indicator and direction arrow, hairline stainless steel ,flat,3-side.door-open button, door-close button, alarm button, overload protection device with audible and visible signal, intercom system with 5 terminals(pit/car/car frame/machine room/supervision room,cable to supervision room excluded), suspended ceiling type 'Voute', emergency lighting, automatic operation for car light and fan, PVC-flooring, light curtain door protection.

轿厢、轿门表面为发纹不锈钢，一个带有微触按钮和层位及方向显示的不锈钢控制面板位于轿厢前壁，轿厢壁三面均配发纹不锈钢圆扶手，开关门按钮，报警按钮，带有声觉和视觉信号的满载及超载保护，五方通话系统（底坑/轿厢/轿顶/机房/监控室，不含至监控室电缆），"Voute"天使型吊顶，应急照明，轿内灯光及风扇自动关闭，PVC地板，154束3D光幕门保护系统，预留轿厢至机房视频及音频电缆（不含摄像头及至监控室电缆）。

A sliding slip cover is installed in portable terminal. The operating button is installed on one side of the main body to connect the component. One end is linked to the operating button, and the other end is linked to the slip cover. It can be opened and closed with the slip cover during operation of operating button.

这种便携式终端的滑动开闭装置是在便携式终端上安装了可滑动的滑盖，其操作按钮，安装在主体的至少一个侧面上，连接构件，一端与上述的操作按钮连为一体，另一端与上述的滑盖连为一体，可在操作按钮的操作下与上述滑盖连动开闭。

Explains how to designate a Button control to be the accept button, also known as the default button.

解释如何将Button控件指定为接受按钮，也称为默认按钮。

This source code is included diamond-shaped button, oval-shaped button, radio button example.

详细说明：此源代码是包含菱形按钮，椭圆形按钮，圆形按钮的例子。

Extend control button to control the button to add bitmap, two focus click, can be the equivalent of two point button.

扩展控钮控件，在按钮上增加位图，有两个焦点点击时，可分别点相当于两个按钮。

Chimborazo and Cotopaxi, took me by the hand.

越过琴博腊索山和科托帕克西山。

This car is in a good condition.

这辆车的状况很好。