查询词典 methylated

Objective To conduct the global assessment of methylated DNA status of CpG islands.

目的 进行人类全基因组CpG岛甲基化谱分析。

First, the fact the team was able to stop PGC-1 alpha being methylated suggests that a drug might be developed to do the same.

第一，研究人员能够阻止PGC-1甲基化的事实表明，也能制造一种有同样效用的药物。

Methylated Micrococcus luteus DNA was prepared with different DNA methylation level by using Hha I DNA methylase and Sephadex G-100 gel filtration.

本文用Hha I DNA甲基化酶为工具酶，制备了不同甲基化水平的Micrococcus IuteusDNA，再用Sephadex G-100凝胶过滤将甲基化了的M.L。

The genes the researchers found to be methylated specifically in the tumor samples might control the conversion of normal cells into cancer cells, Dr. Minna said, but this possibility needs to be tested on a case-by-case basis.

Minna博士还补充到，研究人员发现的这些尤其是在肿瘤标本中发生甲基化的基因，可能控制着正常细胞向癌细胞的转变，但是该可能性需要通过个案原则加以验证。

Peg3 showed completely unmethylated in two cell embryos, and was strongly de novo methylated in morula stages.

结果显示，在正常发育胚胎中，Peg3甲基化印迹在小鼠2细胞胚胎之前就已经被擦除，直到桑椹胚时才被重新建立起来。

Methods Estradiol-randomly methylated β-cyclodextrin (E2-RAMEB) solution, and 70% ethanol solution of estradiol and estradiol nasal spray in 3 different doses 0.16、0.48、1.60 mgkg^(-1 were nasally administrated to rats, respectively. Non-compartment statistical moment method was used in pharmacokinetics study.

对大鼠鼻腔给予雌二醇-随机甲基化β-环糊精包合物的生理盐水溶液、雌二醇乙醇溶液和3种剂量的雌二醇鼻腔喷雾剂，用非隔室模型统计矩法进行了药物动力学研究，并与静脉注射雌二醇相比较计算绝对生物利用度。

Recently, intitial studies had been performed to detect aberrantly methylated genes in the pancreatic juice from patients with PCa as a promising diagnostic strategy.

对肿瘤发生发展过程中表观遗传学机制的深入研究，为肿瘤转移的早期诊断和治疗提供了一个崭新的途径。

In the mutant plant,a genecalled Lcyc is extensively methylated and thus not expressed--and thismethylated state is heritable by subsequent generations of toadflax plants.

在突变体植物中，一个叫Lcyc基因广泛甲基化，因此不能表达。这一甲基化状态在云兰属植物中是能遗传的。

The result of GC showed that HEP-2 was composed with Ara, Man, Glu and the proportion was Ara:Man:Glu = 1:6.28:22.96.HEP was hydrolyzed and partial methylated and partial acetated.

通过本实验测定猴头多糖的组分，确定猴头多糖为一种结合蛋白的硫酸脂多糖，这为进一步研究猴头多糖的精细结构、性质和构效关系提供了科学依据。

Results The DNA was obtained from PPJ through a nasopancreatic tube. Aberrant p16 methylation and K- ras gene mutation were detected in the same samples of PPJ. Sensitivity,specificity,positive predictive values,negative predictive values and accuracy of HE staining for pancreatic cancer were 40%,100%,100%,45.4% and 60.0%,respectively. Of the 20 cases of pancreatic cancer,K- ras gene mutation was detected in 14 (70%) and the p16 gene was shown to be methylated in 7 (35%). Of the 8 cases of chronic pancreatitis,K-ras gene mutation was detected in 2 (25%). Of the 2 cases of mucinous cystoadenoma of pancreas,K-ras gene mutation was detected in 1 (50%). Aberrant methylation of p16 was not detected in pancreatic juice samples from patients with chronic pancreatitis and mucinous cystoadenoma of pancreas.

结果 所有胰液标本均成功抽提出DNA，30例胰腺疾病病人胰液标本同时进行了K-ras基因突变和p16基因启动子区5′CpG岛甲基化检测，其中20例胰腺癌病人胰液中K-ras基因突变率为70%（14/20），p16基因甲基化率为35%（7/20），8例慢性胰腺炎中K-ras基因突变率为25%（2/8），2例胰腺囊腺瘤病人中K-ras基因突变率为50%（1/2），慢性胰腺炎和胰腺囊腺瘤病人胰液中无p16基因甲基化。

Chrysanthemum of 10 thousand birthday is lax to edaphic requirement, with the arenaceous qualitative loam with fecund, good drainage had better.

万寿菊对土壤要求不严，以肥沃。排水良好的砂质壤土为好。

He unstepped the mast and furled the sail and tied it.

他拔下桅杆，把帆卷起，系住。