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There were no statistically differences between the 8th~ 14thday, the 15th - 21th day post-BC and the control group. During the rt~24tkday post-BC , pycnosis degeneration or necrosis neurons of the locus cerebral cortex, dorsal hippocampus, dentate fornix were significantly increased, then decreased gradually, but recovered to normal by the 24thday after BC, and especially in parietal cortex and piriform cortex the necrosis neurons were significantly increased than temporal cortex , and there were no statistically difference berween the left and the right side. Pycnosis degeneration or necrosis neurons in the brainstem reticular formation were markedly increased in the 4thday after BC, and there were no statistically difference among the other groups and the control group.

与对照组相比，BC后在大脑皮质、背侧海马和齿状回部位，固缩变性和不完全坏死细胞数先显著增加(P＜0.05)，然后逐渐减少，至24d基本恢复正常；顶叶、梨状皮质比颞叶皮质变性坏死细胞多，差异有高度显著性(P＜0.01)；大脑左侧比右侧变性坏死细胞稍少但差异无显著性；在BC后4d，脑桥核、斜方体核平面的脑干网状结构中固缩变性和不完全坏死细胞数明显增多(P＜0.05)，其它组间无显著性差异。

The number of pyknotic cells in the JWA knock-down cells was markedly greater than in vector control cells following CdCl_2 exposure (20μM for 12 h).

结果显示，与对照相比，当JWA蛋白表达缺陷时，加重了CdCl_2诱导的HEK-293T细胞凋亡(P＜0.05)。

MSG could insult the functions and structures of specific brain areas of adult mice through blood-brain barrier. The ability of discrimination learning in Y-maze was affected markedly, especially in 4. 0g/kg MSG group, meanwhile, dark pyknotic and loss of neurons were shown in arcuate nucleus of hypothalamus, but not in hippocampus. Consistent changes occured in mitochondrial membrane protein bound 〓 by 〓-fluoresent probe, i.

MSG可以透过成年小鼠血脑屏障产生神经毒性作用。4.0g/kg MSG对小鼠空间分辨学习能力的损伤程度较2.5g/kg MSG更为明显，同时下丘脑弓状核神经元出现核固缩及神经元数目明显减少，相同处理未引起海马神经元的明显变化。

The results indicate that the presence of GSH increased the expression of exoY、exoS、phzA1 and gacA,while no difference was observed with others virulence factor genes tested.PAO1 produced markedly less pyocyanin than the wild type strain PAOIP＜0.01Treating with GSH, the PCN production of PAOI(△gshB was increased from 0.47μg/mL to 1.73μg/mL (P＜0.01),the PCN production of PAO1 increased from 1.3μg/mL to 1.9μg/mL(P＜0.05),this result indicates that GSH upregulates PCN production.

结果发现，GSH对启动子库中exoS、exoY、phzA1和gacA等致病性因子的表达有促进作用，对其余测试过的致病性因子则没有明显影响；铜绿假单胞菌分泌的重要致病因子绿脓菌素(pyocyanin，PCN)的含量，在PAO1中远低于PAO1P＜0.01加入GSH后，PCN平均含量在PAO1(△gshB中从0.47μg/mL提高到1.73μg/mL，差异十分显著(P＜0.01)，在PAO1中从1.3μg/mL提高到1.9μg/mL，差异显著(P＜0.05)，表明GSH对铜绿假单胞菌生产PCN有促进作用。

Var. pyramidalis is not positively correlated with ion concentration in growth environment, the capacity of selective absorption and transport of ions in Populus alba L. var. pyramidali under salt stress in drainage canal is higher than Populus alba L. var. pyramidal is of normal growth in irrigation canal. Under salt stress, the concentration of K(superscript +)、Na(superscript +) of roots and leave of Populus alba L. var. pyramidalis have changed, the concentration of K(superscript +) of roots and leave dropt the concentration of Na(superscript +) of roots markedly increased, the concentration of Ca(superscript 2+), Mg(superscript 2+) have slightly changed, the concentration of Ca(superscript 2+) of roots dropted, the concentration of Mg(superscript 2+) increased, the concentration of Ca(superscript 2+), Mg(superscript 2+) of leave increased.

主要结论为：新疆杨各器官的离子含量与生长环境中的离子浓度不存在正相关趋势；排渠盐胁迫下生长的新疆杨对离子选择吸收和运输的能力高于灌渠正常生长的新疆杨；盐胁迫下，新疆杨根和叶中K、Na的浓度发生了明显的变化，K浓度在根和叶中呈下降趋势，Na浓度在根中明显增加，根和叶中Ca(上标 2+)、Mg(上标 2+)浓度的变化趋势略缓，根中Ca(上标 2+)浓度下降，Mg(上标 2+)浓度增加，叶中Ca(上标 2+)、Mg(上标 2+)浓度有所上升。

The colon temperatures were measured by a thermistor and the cytosolic free calcium concentration ([Ca2+]i) in dissociated brain cells was measured by Fura 2-AM. The results demonstrated that the pyretic action of egtazic acid (0.6 μmol, icv) was markedly inhibited by DEX (5 mg/kg,iv), but DEX (60-120 μmol/L) did′t affect [Ca2+]i in dissociated hypothalamus cells. Actinomycin D, which interferes with gene transcription (3 nmol, icv), completely abolished the antipyretic action of DEX on egtazic acid-induced fever.

结果发现：脑室灌注乙二醇双(2-氨基乙醚)四乙酸(0.6 nmol)引起家兔结肠温度明显升高，静脉注射地塞米松(5 mg/kg)显著抑制家兔乙二醇双(2-氨基乙醚)四乙酸性发热，地塞米松(60-120 μmol/L)并不影响下丘脑细胞内[Ca2+]i，而事先脑室灌注抑制基因转录的放线菌素D(3 nmol)则完全取消了地塞米松对乙二醇双(2-氨基乙醚)四乙酸性发热的解热作用。

Queer: markedly from the norm "Now, my suspicion is that the universe is not only queerer than we suppose, but queerer than we can suppose ."

&现在，我的怀疑是宇宙不但比我们所假想的要奇异，而且比我们能假想的还要奇异。& JBS霍尔丹

Proper amount quinhydrone markedly increased the yields and improved the qualities of the two vegetables.

适宜用量的醌氢醌可提高蕹菜、小白菜产量和品质。

The resuit indicates that optimal scheme meets the design reguirements, the parameters of the gear in each step are more reasonable and the volume of the main reducer is decreased markedly.

计算结果表明，优化方案在满足设计要求的前提下，各级齿轮的参数更为合理，主机构减速器的体积显著下降。

Results Intra-articular hemorrhage was observed in 1 patient and intra-osseous hemorrhage in 7 patients. The injury of retinacular arteries and reduction of blood supply were found in each case. In the presence of hip traction, blood flow of retinacular arteries reduced markedly. Few branches and little femoral head blood perfusion were observed in all of retinacular arteries, while hip joint was internally rotated with the sick leg straightened in the patients.

结果 12例中髋关节囊内出血1例，骨内出血7例， 12例均出现持带动脉损伤和血供减少；患髋牵引时支持带动脉供血减少；髋关节维持伸直内旋位时所有支持带动脉无明确显影或仅显示其主干。

There had been a moment during the breakfast meeting, though, after the backslapping and the small talk and when all of us were seated, with Vice President Cheney eating his eggs Benedict impassively and Karl Rove at the far end of the table discreetly checking his BlackBerry, that I witnessed a different side of the man.

那次早餐会期间，在表示过关心和寒暄以后，我们所有人坐了下来，我注意观察了一下，副总统切尼面无表情地吃着班尼迪克蛋（Eggs benedict，源自美国，以英式松饼、火腿、水煮蛋以及荷兰酱组合而成），卡尔。罗夫在餐桌的远端谨慎地经常查看他的黑莓手机，我目睹了他所不为人知的一面。

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